EA037951B1 - Фенольное соединение и его комбинация с бензодиазепином, конденсированным с 1,4-дигидропиридином, для лечения поражений центральной нервной и сосудистой систем - Google Patents
Фенольное соединение и его комбинация с бензодиазепином, конденсированным с 1,4-дигидропиридином, для лечения поражений центральной нервной и сосудистой систем Download PDFInfo
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- EA037951B1 EA037951B1 EA201892462A EA201892462A EA037951B1 EA 037951 B1 EA037951 B1 EA 037951B1 EA 201892462 A EA201892462 A EA 201892462A EA 201892462 A EA201892462 A EA 201892462A EA 037951 B1 EA037951 B1 EA 037951B1
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Classifications
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- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
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- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A61K9/2022—Organic macromolecular compounds
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- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A61P25/00—Drugs for disorders of the nervous system
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Landscapes
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- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU2016000059A CU24576B1 (es) | 2016-05-04 | 2016-05-04 | Compuesto fenólico y combinación del mismo con una benzodiazepina fusionada a 1,4-dihidropiridina para el tratamiento de afecciones del sistema nervioso central y vascular |
| PCT/CU2017/050003 WO2017190714A1 (es) | 2016-05-04 | 2017-05-03 | Compuesto fenólico y combinación del mismo con una benzodiazepina fusionada a 1,4-dihidropiridina para el tratamiento de afecciones del sistema nervioso central y vascular |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201892462A1 EA201892462A1 (ru) | 2019-07-31 |
| EA037951B1 true EA037951B1 (ru) | 2021-06-11 |
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| EA201892462A EA037951B1 (ru) | 2016-05-04 | 2017-05-03 | Фенольное соединение и его комбинация с бензодиазепином, конденсированным с 1,4-дигидропиридином, для лечения поражений центральной нервной и сосудистой систем |
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| US (1) | US10722491B2 (https=) |
| EP (1) | EP3453704B1 (https=) |
| JP (1) | JP6997995B2 (https=) |
| KR (1) | KR102416478B1 (https=) |
| CN (1) | CN109476627B (https=) |
| AR (1) | AR108370A1 (https=) |
| AU (1) | AU2017259749C1 (https=) |
| BR (1) | BR112018072579B1 (https=) |
| CA (1) | CA3023073C (https=) |
| CL (1) | CL2018003114A1 (https=) |
| CO (1) | CO2018011927A2 (https=) |
| CU (1) | CU24576B1 (https=) |
| EA (1) | EA037951B1 (https=) |
| ES (1) | ES2878579T3 (https=) |
| MX (1) | MX384967B (https=) |
| PH (1) | PH12018502327A1 (https=) |
| SG (1) | SG11201809843SA (https=) |
| WO (1) | WO2017190714A1 (https=) |
| ZA (1) | ZA201808161B (https=) |
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| CU20160058A7 (es) | 2016-05-04 | 2017-12-08 | Centro De Investigación Y Desarrollo De Medicamentos (Cidem) Organizacion Superior De Desarrollo Emp | Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular |
| AU2019361735A1 (en) * | 2018-10-16 | 2021-05-27 | Saban Ventures Pty Limited | Apparatus and method for cleaning a medical device |
| CU20190114A7 (es) | 2019-12-26 | 2021-08-06 | Centro De Investig Y Desarrollo De Medicamentos Cidem | Combinación para simultáneamente incrementar la eficacia analgésica de la morfina y reducir su dependencia física |
| BR112022012699A2 (pt) * | 2019-12-26 | 2022-09-06 | Centro De Investig Y Desarrollo De Medicamentos Cidem | Uso de um derivado de benzodiazepina e método de tratamento de lesão cerebral traumática |
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| DE69202564T2 (de) | 1992-07-17 | 1995-09-28 | Biogal Gyogyszergyar | Verfahren zur Herstellung von 1,3-Dioxan-4,6-Dionderivaten. |
| JPH11180975A (ja) | 1997-10-13 | 1999-07-06 | Chemiprokasei Kaisha Ltd | アミノメチレンジオキサン誘導体、その製造方法および用途 |
| JP5299810B2 (ja) | 2004-02-27 | 2013-09-25 | アムジエン・インコーポレーテツド | 代謝疾患の治療に使用するための、化合物、薬学的組成物及び方法 |
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| BR112018072579A2 (pt) | 2019-02-19 |
| EP3453704B1 (en) | 2021-06-16 |
| JP2019516791A (ja) | 2019-06-20 |
| US20190133996A1 (en) | 2019-05-09 |
| AR108370A1 (es) | 2018-08-15 |
| AU2017259749A1 (en) | 2018-12-20 |
| CA3023073A1 (en) | 2017-11-09 |
| CA3023073C (en) | 2022-08-30 |
| AU2017259749B2 (en) | 2021-08-19 |
| CN109476627B (zh) | 2021-06-15 |
| CU20160059A7 (es) | 2017-12-08 |
| KR20210025138A (ko) | 2021-03-09 |
| AU2017259749C1 (en) | 2021-12-02 |
| JP6997995B2 (ja) | 2022-02-04 |
| SG11201809843SA (en) | 2018-12-28 |
| EP3453704A1 (en) | 2019-03-13 |
| ZA201808161B (en) | 2021-10-27 |
| MX384967B (es) | 2025-03-14 |
| CN109476627A (zh) | 2019-03-15 |
| BR112018072579B1 (pt) | 2024-02-20 |
| CO2018011927A2 (es) | 2019-02-08 |
| EA201892462A1 (ru) | 2019-07-31 |
| KR102416478B1 (ko) | 2022-07-04 |
| CL2018003114A1 (es) | 2019-06-14 |
| US10722491B2 (en) | 2020-07-28 |
| ES2878579T3 (es) | 2021-11-19 |
| PH12018502327A1 (en) | 2019-09-02 |
| WO2017190714A1 (es) | 2017-11-09 |
| MX2018013422A (es) | 2019-08-16 |
| CU24576B1 (es) | 2022-02-04 |
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