CU20160058A7 - Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular - Google Patents
Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascularInfo
- Publication number
- CU20160058A7 CU20160058A7 CUP2016000058A CU20160058A CU20160058A7 CU 20160058 A7 CU20160058 A7 CU 20160058A7 CU P2016000058 A CUP2016000058 A CU P2016000058A CU 20160058 A CU20160058 A CU 20160058A CU 20160058 A7 CU20160058 A7 CU 20160058A7
- Authority
- CU
- Cuba
- Prior art keywords
- central
- nervous system
- benzodiazepina
- activity
- derived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
<p>Compuesto de fórmula I, sus derivados y composiciones farmacéuticas que los contienen para el tratamiento de enfermedades del sistema nervioso central y vascular, especialmente trastornos neurodegenerativos, con deterioro cognitivo, enfermedades asociadas al estres oxidativo, enfermedades que cursan con disfunción mitocondrial, enfermedad de Parkinson y dolor neuropático, así como procesos patológicos asociados con el envejecimiento. ESPACIO PARA FÓRMULA</p>
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CUP2016000058A CU20160058A7 (es) | 2016-05-04 | 2016-05-04 | Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular |
EP17732729.3A EP3470414B1 (en) | 2016-05-04 | 2017-05-03 | Benzodiazepine derivative with activity on the central nervous and vascular systems |
BR112018072588-9A BR112018072588B1 (pt) | 2016-05-04 | 2017-05-03 | Uso de um composto de benzodiacepina |
SG11201809845TA SG11201809845TA (en) | 2016-05-04 | 2017-05-03 | Benzodiazepine product with activity on the central nervous and vascular systems |
PCT/CU2017/050002 WO2017190713A1 (es) | 2016-05-04 | 2017-05-03 | Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular |
NZ748959A NZ748959A (en) | 2016-05-04 | 2017-05-03 | Benzodiazepine derivative with activity on the central nervous and vascular systems |
MX2018013405A MX2018013405A (es) | 2016-05-04 | 2017-05-03 | Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular. |
US16/099,116 US11098039B2 (en) | 2016-05-04 | 2017-05-03 | Benzodiazepine product with activity on the central nervous and vascular systems |
KR1020187035040A KR102428383B1 (ko) | 2016-05-04 | 2017-05-03 | 중추신경계 및 혈관계에 대한 활성을 가진 벤조디아제핀 생성물 |
DK17732729.3T DK3470414T3 (da) | 2016-05-04 | 2017-05-03 | Benzodiazepinderivat med aktivitet på centralnerve- og karsystemerne |
CN201780041572.6A CN110114356B (zh) | 2016-05-04 | 2017-05-03 | 具有对中枢神经系统和血管系统的活性的苯并二氮卓衍生物 |
CA3023105A CA3023105C (en) | 2016-05-04 | 2017-05-03 | Benzodiazepine derivative with activity on the central nervous and vascular systems |
ES17732729T ES2902992T3 (es) | 2016-05-04 | 2017-05-03 | Derivado de benzodiazepina con actividad sobre los sistemas vascular y nervioso central |
EA201892461A EA201892461A1 (ru) | 2016-05-04 | 2017-05-03 | Продукт бензодиазепина с активностью на центральную нервную и сердечно-сосудистую системы |
SI201731044T SI3470414T1 (sl) | 2016-05-04 | 2017-05-03 | Derivat benzodiazepina, ki deluje na centralni živčni in žilni sistem |
JP2019510748A JP7078959B2 (ja) | 2016-05-04 | 2017-05-03 | 中枢神経系及び血管系での活性を持つベンゾジアゼピン誘導体 |
AU2017259748A AU2017259748B2 (en) | 2016-05-04 | 2017-05-03 | Benzodiazepine derivative with activity on the central nervous and vascular systems |
ARP170101152A AR108369A1 (es) | 2016-05-04 | 2017-05-04 | Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular |
CL2018003113A CL2018003113A1 (es) | 2016-05-04 | 2018-10-31 | Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular. |
ZA2018/08162A ZA201808162B (en) | 2016-05-04 | 2018-12-03 | Benzodiazepine derivative with activity on the central nervous and vascular systems |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CUP2016000058A CU20160058A7 (es) | 2016-05-04 | 2016-05-04 | Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular |
Publications (1)
Publication Number | Publication Date |
---|---|
CU20160058A7 true CU20160058A7 (es) | 2017-12-08 |
Family
ID=59215419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CUP2016000058A CU20160058A7 (es) | 2016-05-04 | 2016-05-04 | Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular |
Country Status (20)
Country | Link |
---|---|
US (1) | US11098039B2 (es) |
EP (1) | EP3470414B1 (es) |
JP (1) | JP7078959B2 (es) |
KR (1) | KR102428383B1 (es) |
CN (1) | CN110114356B (es) |
AR (1) | AR108369A1 (es) |
AU (1) | AU2017259748B2 (es) |
BR (1) | BR112018072588B1 (es) |
CA (1) | CA3023105C (es) |
CL (1) | CL2018003113A1 (es) |
CU (1) | CU20160058A7 (es) |
DK (1) | DK3470414T3 (es) |
EA (1) | EA201892461A1 (es) |
ES (1) | ES2902992T3 (es) |
MX (1) | MX2018013405A (es) |
NZ (1) | NZ748959A (es) |
SG (1) | SG11201809845TA (es) |
SI (1) | SI3470414T1 (es) |
WO (1) | WO2017190713A1 (es) |
ZA (1) | ZA201808162B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CU20190114A7 (es) | 2019-12-26 | 2021-08-06 | Centro De Investig Y Desarrollo De Medicamentos Cidem | Combinación para simultáneamente incrementar la eficacia analgésica de la morfina y reducir su dependencia física |
BR112022012699A2 (pt) | 2019-12-26 | 2022-09-06 | Centro De Investig Y Desarrollo De Medicamentos Cidem | Uso de um derivado de benzodiazepina e método de tratamento de lesão cerebral traumática |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110288070A1 (en) * | 2008-05-05 | 2011-11-24 | ROGERS Kathryn | Methods for treating cognitive disorders using inhibitors of histone deacetylase |
CU20090172A7 (es) * | 2009-10-09 | 2011-10-05 | Ct De Investigación Y Desarrollo De Medicamentos | Sistemas tricíclicos y tetracíclicos con actividad sobre el sistema nervioso central y vascular |
CU24576B1 (es) | 2016-05-04 | 2022-02-04 | Centro De Investig Y Desarrollo De Medicamentos Cidem | Compuesto fenólico y combinación del mismo con una benzodiazepina fusionada a 1,4-dihidropiridina para el tratamiento de afecciones del sistema nervioso central y vascular |
-
2016
- 2016-05-04 CU CUP2016000058A patent/CU20160058A7/es unknown
-
2017
- 2017-05-03 AU AU2017259748A patent/AU2017259748B2/en not_active Ceased
- 2017-05-03 BR BR112018072588-9A patent/BR112018072588B1/pt active IP Right Grant
- 2017-05-03 SI SI201731044T patent/SI3470414T1/sl unknown
- 2017-05-03 CA CA3023105A patent/CA3023105C/en active Active
- 2017-05-03 MX MX2018013405A patent/MX2018013405A/es unknown
- 2017-05-03 SG SG11201809845TA patent/SG11201809845TA/en unknown
- 2017-05-03 EP EP17732729.3A patent/EP3470414B1/en active Active
- 2017-05-03 JP JP2019510748A patent/JP7078959B2/ja active Active
- 2017-05-03 ES ES17732729T patent/ES2902992T3/es active Active
- 2017-05-03 DK DK17732729.3T patent/DK3470414T3/da active
- 2017-05-03 KR KR1020187035040A patent/KR102428383B1/ko active IP Right Grant
- 2017-05-03 NZ NZ748959A patent/NZ748959A/en unknown
- 2017-05-03 CN CN201780041572.6A patent/CN110114356B/zh active Active
- 2017-05-03 US US16/099,116 patent/US11098039B2/en active Active
- 2017-05-03 EA EA201892461A patent/EA201892461A1/ru unknown
- 2017-05-03 WO PCT/CU2017/050002 patent/WO2017190713A1/es unknown
- 2017-05-04 AR ARP170101152A patent/AR108369A1/es unknown
-
2018
- 2018-10-31 CL CL2018003113A patent/CL2018003113A1/es unknown
- 2018-12-03 ZA ZA2018/08162A patent/ZA201808162B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN110114356A (zh) | 2019-08-09 |
US20190270738A1 (en) | 2019-09-05 |
BR112018072588A2 (pt) | 2019-02-19 |
NZ748959A (en) | 2024-02-23 |
CA3023105A1 (en) | 2017-11-09 |
AU2017259748B2 (en) | 2021-08-05 |
JP7078959B2 (ja) | 2022-06-01 |
ZA201808162B (en) | 2021-08-25 |
SI3470414T1 (sl) | 2022-03-31 |
JP2019519600A (ja) | 2019-07-11 |
AR108369A1 (es) | 2018-08-15 |
MX2018013405A (es) | 2019-08-16 |
US11098039B2 (en) | 2021-08-24 |
SG11201809845TA (en) | 2018-12-28 |
EP3470414A1 (en) | 2019-04-17 |
EA201892461A1 (ru) | 2019-04-30 |
AU2017259748A1 (en) | 2018-12-20 |
WO2017190713A1 (es) | 2017-11-09 |
EP3470414B1 (en) | 2021-10-13 |
KR20210025137A (ko) | 2021-03-09 |
CN110114356B (zh) | 2021-09-24 |
CA3023105C (en) | 2023-07-18 |
DK3470414T3 (da) | 2022-01-17 |
BR112018072588B1 (pt) | 2024-02-20 |
KR102428383B1 (ko) | 2022-08-02 |
ES2902992T3 (es) | 2022-03-30 |
CL2018003113A1 (es) | 2019-04-12 |
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