SG11201809845TA - Benzodiazepine product with activity on the central nervous and vascular systems - Google Patents
Benzodiazepine product with activity on the central nervous and vascular systemsInfo
- Publication number
- SG11201809845TA SG11201809845TA SG11201809845TA SG11201809845TA SG11201809845TA SG 11201809845T A SG11201809845T A SG 11201809845TA SG 11201809845T A SG11201809845T A SG 11201809845TA SG 11201809845T A SG11201809845T A SG 11201809845TA SG 11201809845T A SG11201809845T A SG 11201809845TA
- Authority
- SG
- Singapore
- Prior art keywords
- central nervous
- vascular systems
- activity
- benzodiazepine
- product
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
BENZODIAZEPINE PRODUCT WITH ACTIVITY ON THE CENTRAL NERVOUS AND VASCULAR SYSTEMS The invention relates to a compound of formula III, the derivatives thereof, and pharmaceutical compositions containing same for the treatment of diseases of the central nervous and vascular systems, particularly neurodegenerative disorders with cognitive deterioration, diseases associated with oxidative stress, diseases associated with mitochondrial dysfunction, Parkinson's disease and neuropathic pain, as well as the pathological processes associated with aging. [Figure 2]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CUP2016000058A CU20160058A7 (en) | 2016-05-04 | 2016-05-04 | DERIVED FROM BENZODIAZEPINA WITH ACTIVITY ON THE CENTRAL AND VASCULAR NERVOUS SYSTEM |
PCT/CU2017/050002 WO2017190713A1 (en) | 2016-05-04 | 2017-05-03 | Benzodiazepine derivative with activity on the central nervous and vascular systems |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201809845TA true SG11201809845TA (en) | 2018-12-28 |
Family
ID=59215419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201809845TA SG11201809845TA (en) | 2016-05-04 | 2017-05-03 | Benzodiazepine product with activity on the central nervous and vascular systems |
Country Status (20)
Country | Link |
---|---|
US (1) | US11098039B2 (en) |
EP (1) | EP3470414B1 (en) |
JP (1) | JP7078959B2 (en) |
KR (1) | KR102428383B1 (en) |
CN (1) | CN110114356B (en) |
AR (1) | AR108369A1 (en) |
AU (1) | AU2017259748B2 (en) |
BR (1) | BR112018072588B1 (en) |
CA (1) | CA3023105C (en) |
CL (1) | CL2018003113A1 (en) |
CU (1) | CU20160058A7 (en) |
DK (1) | DK3470414T3 (en) |
EA (1) | EA201892461A1 (en) |
ES (1) | ES2902992T3 (en) |
MX (1) | MX2018013405A (en) |
NZ (1) | NZ748959A (en) |
SG (1) | SG11201809845TA (en) |
SI (1) | SI3470414T1 (en) |
WO (1) | WO2017190713A1 (en) |
ZA (1) | ZA201808162B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CU20190114A7 (en) * | 2019-12-26 | 2021-08-06 | Centro De Investig Y Desarrollo De Medicamentos Cidem | COMBINATION TO SIMULTANEOUSLY INCREASE THE ANALGESIC EFFECTIVENESS OF MORPHINE AND REDUCE ITS PHYSICAL DEPENDENCE |
BR112022012699A2 (en) * | 2019-12-26 | 2022-09-06 | Centro De Investig Y Desarrollo De Medicamentos Cidem | USE OF A BENZODIAZEPINE DERIVATIVE AND METHOD OF TREATMENT OF TRAUMATIC BRAIN INJURY |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009137462A2 (en) * | 2008-05-05 | 2009-11-12 | Envivo Pharmaceuticals, Inc. | Methods for treating cognitive disorders using inhibitors of histone deacetylase |
CU20090172A7 (en) * | 2009-10-09 | 2011-10-05 | Ct De Investigación Y Desarrollo De Medicamentos | TRICYCLIC AND TETRACYCLIC SYSTEMS WITH ACTIVITY ON THE CENTRAL AND VASCULAR NERVOUS SYSTEM |
CU24576B1 (en) | 2016-05-04 | 2022-02-04 | Centro De Investig Y Desarrollo De Medicamentos Cidem | PHENOLIC COMPOUND AND COMBINATION THEREOF WITH A BENZODIAZEPINE FUSED TO 1,4-DIHYDROPYRIDINE FOR THE TREATMENT OF DISORDERS OF THE CENTRAL AND VASCULAR NERVOUS SYSTEM |
-
2016
- 2016-05-04 CU CUP2016000058A patent/CU20160058A7/en unknown
-
2017
- 2017-05-03 EA EA201892461A patent/EA201892461A1/en unknown
- 2017-05-03 NZ NZ748959A patent/NZ748959A/en unknown
- 2017-05-03 CA CA3023105A patent/CA3023105C/en active Active
- 2017-05-03 AU AU2017259748A patent/AU2017259748B2/en not_active Ceased
- 2017-05-03 US US16/099,116 patent/US11098039B2/en active Active
- 2017-05-03 CN CN201780041572.6A patent/CN110114356B/en active Active
- 2017-05-03 JP JP2019510748A patent/JP7078959B2/en active Active
- 2017-05-03 KR KR1020187035040A patent/KR102428383B1/en active IP Right Grant
- 2017-05-03 SG SG11201809845TA patent/SG11201809845TA/en unknown
- 2017-05-03 SI SI201731044T patent/SI3470414T1/en unknown
- 2017-05-03 MX MX2018013405A patent/MX2018013405A/en unknown
- 2017-05-03 BR BR112018072588-9A patent/BR112018072588B1/en active IP Right Grant
- 2017-05-03 EP EP17732729.3A patent/EP3470414B1/en active Active
- 2017-05-03 ES ES17732729T patent/ES2902992T3/en active Active
- 2017-05-03 WO PCT/CU2017/050002 patent/WO2017190713A1/en unknown
- 2017-05-03 DK DK17732729.3T patent/DK3470414T3/en active
- 2017-05-04 AR ARP170101152A patent/AR108369A1/en unknown
-
2018
- 2018-10-31 CL CL2018003113A patent/CL2018003113A1/en unknown
- 2018-12-03 ZA ZA2018/08162A patent/ZA201808162B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CL2018003113A1 (en) | 2019-04-12 |
NZ748959A (en) | 2024-02-23 |
BR112018072588A2 (en) | 2019-02-19 |
ZA201808162B (en) | 2021-08-25 |
AU2017259748A1 (en) | 2018-12-20 |
ES2902992T3 (en) | 2022-03-30 |
BR112018072588B1 (en) | 2024-02-20 |
WO2017190713A1 (en) | 2017-11-09 |
US20190270738A1 (en) | 2019-09-05 |
EP3470414A1 (en) | 2019-04-17 |
EA201892461A1 (en) | 2019-04-30 |
AR108369A1 (en) | 2018-08-15 |
AU2017259748B2 (en) | 2021-08-05 |
CN110114356B (en) | 2021-09-24 |
SI3470414T1 (en) | 2022-03-31 |
KR102428383B1 (en) | 2022-08-02 |
EP3470414B1 (en) | 2021-10-13 |
DK3470414T3 (en) | 2022-01-17 |
KR20210025137A (en) | 2021-03-09 |
JP2019519600A (en) | 2019-07-11 |
CN110114356A (en) | 2019-08-09 |
CA3023105A1 (en) | 2017-11-09 |
MX2018013405A (en) | 2019-08-16 |
CA3023105C (en) | 2023-07-18 |
US11098039B2 (en) | 2021-08-24 |
JP7078959B2 (en) | 2022-06-01 |
CU20160058A7 (en) | 2017-12-08 |
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