UY36305A - Compuestos de esteroides c-20, sus composiciones y usos para tratar lesión cerebral traumática (tbi), que incluyen conmociones cerebrales. - Google Patents
Compuestos de esteroides c-20, sus composiciones y usos para tratar lesión cerebral traumática (tbi), que incluyen conmociones cerebrales.Info
- Publication number
- UY36305A UY36305A UY0001036305A UY36305A UY36305A UY 36305 A UY36305 A UY 36305A UY 0001036305 A UY0001036305 A UY 0001036305A UY 36305 A UY36305 A UY 36305A UY 36305 A UY36305 A UY 36305A
- Authority
- UY
- Uruguay
- Prior art keywords
- tbi
- compositions
- conmotions
- steroid compounds
- brain injury
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a compuestos de esteroides C-20, sus composiciones y métodos de uso para tratar, minimizar y/o evitar una lesión cerebral traumática (TBI), que incluyen TBI grave, TBI moderada y TBI leve, que incluyen las conmociones cerebrales.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462051898P | 2014-09-17 | 2014-09-17 | |
US201462052457P | 2014-09-18 | 2014-09-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY36305A true UY36305A (es) | 2016-04-29 |
Family
ID=55533838
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001036305A UY36305A (es) | 2014-09-17 | 2015-09-17 | Compuestos de esteroides c-20, sus composiciones y usos para tratar lesión cerebral traumática (tbi), que incluyen conmociones cerebrales. |
Country Status (18)
Country | Link |
---|---|
US (1) | US20160168190A1 (es) |
EP (1) | EP3194417B1 (es) |
JP (1) | JP2017527603A (es) |
KR (1) | KR20170103745A (es) |
CN (1) | CN107108689A (es) |
AU (1) | AU2015317652A1 (es) |
BR (1) | BR112017005168A2 (es) |
CA (1) | CA2961630A1 (es) |
CL (1) | CL2017000644A1 (es) |
EA (1) | EA201790430A1 (es) |
ES (1) | ES2855993T3 (es) |
IL (1) | IL251239A0 (es) |
PH (1) | PH12017500500A1 (es) |
SG (1) | SG11201702118YA (es) |
TW (1) | TW201625660A (es) |
UY (1) | UY36305A (es) |
WO (1) | WO2016044559A1 (es) |
ZA (1) | ZA201701975B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023069126A1 (en) | 2021-10-19 | 2023-04-27 | Odyssey Health, Inc. | Breath-powered nasal devices for treatment of traumatic brain injury (tbi), including concussion, and methods and methods |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3248390A (en) * | 1963-10-10 | 1966-04-26 | Syntex Corp | 19-nor-10alpha-pregnene and delta1(10)-19-nor-5alpha-pregnene compounds |
FR2097045A1 (en) * | 1970-07-30 | 1972-03-03 | Roussel Uclaf | 17-ethynylgon-4-en-3-ones - with progestomimetic activity useful as contraceptives and for gynaecological disorders |
US5792757A (en) * | 1994-08-04 | 1998-08-11 | Pherin Pharmaceuticals | 19-nor-pregnane steroids as neurochemical initiators of change in human hypothalamic function |
WO2009108804A2 (en) * | 2008-02-26 | 2009-09-03 | Emory University | Steroid analogues for neuroprotection |
CN108976272B (zh) * | 2011-10-14 | 2021-05-25 | 萨奇治疗股份有限公司 | 3,3-二取代的19-去甲孕甾烷化合物、组合物、及其用途 |
CN103073612B (zh) * | 2013-02-04 | 2015-11-04 | 山东大学 | 醋酸乌利司他关键中间体的制备方法 |
UY36741A (es) * | 2015-06-21 | 2016-12-30 | Prevacus Inc | Compuesto de esteroide c-20, sus composiciones y usos para tratar la lesión cerebral traumática (tbi), que incluye las conmociones cerebrales |
-
2015
- 2015-09-17 KR KR1020177010293A patent/KR20170103745A/ko unknown
- 2015-09-17 UY UY0001036305A patent/UY36305A/es not_active Application Discontinuation
- 2015-09-17 BR BR112017005168A patent/BR112017005168A2/pt not_active IP Right Cessation
- 2015-09-17 CN CN201580056187.XA patent/CN107108689A/zh active Pending
- 2015-09-17 EA EA201790430A patent/EA201790430A1/ru unknown
- 2015-09-17 CA CA2961630A patent/CA2961630A1/en active Pending
- 2015-09-17 EP EP15843046.2A patent/EP3194417B1/en active Active
- 2015-09-17 JP JP2017515184A patent/JP2017527603A/ja active Pending
- 2015-09-17 ES ES15843046T patent/ES2855993T3/es active Active
- 2015-09-17 US US14/857,331 patent/US20160168190A1/en active Pending
- 2015-09-17 TW TW104130830A patent/TW201625660A/zh unknown
- 2015-09-17 WO PCT/US2015/050633 patent/WO2016044559A1/en active Application Filing
- 2015-09-17 AU AU2015317652A patent/AU2015317652A1/en not_active Abandoned
- 2015-09-17 SG SG11201702118YA patent/SG11201702118YA/en unknown
-
2017
- 2017-03-15 PH PH12017500500A patent/PH12017500500A1/en unknown
- 2017-03-16 CL CL2017000644A patent/CL2017000644A1/es unknown
- 2017-03-16 IL IL251239A patent/IL251239A0/en unknown
- 2017-03-22 ZA ZA2017/01975A patent/ZA201701975B/en unknown
Also Published As
Publication number | Publication date |
---|---|
PH12017500500A1 (en) | 2017-08-30 |
BR112017005168A2 (pt) | 2018-01-23 |
SG11201702118YA (en) | 2017-04-27 |
TW201625660A (zh) | 2016-07-16 |
EP3194417A1 (en) | 2017-07-26 |
KR20170103745A (ko) | 2017-09-13 |
CA2961630A1 (en) | 2016-03-24 |
EP3194417B1 (en) | 2020-10-28 |
ES2855993T3 (es) | 2021-09-27 |
WO2016044559A1 (en) | 2016-03-24 |
US20160168190A1 (en) | 2016-06-16 |
EP3194417A4 (en) | 2018-12-19 |
EA201790430A1 (ru) | 2017-08-31 |
ZA201701975B (en) | 2019-06-26 |
IL251239A0 (en) | 2017-05-29 |
CL2017000644A1 (es) | 2018-04-02 |
AU2015317652A1 (en) | 2017-04-06 |
CN107108689A (zh) | 2017-08-29 |
JP2017527603A (ja) | 2017-09-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RDES | Application refused |
Effective date: 20230508 |