EA036644B1 - Приводимый в действие спокойным дыханием ингалятор сухого порошка с активацией с помощью миниатюрного датчика давления - Google Patents
Приводимый в действие спокойным дыханием ингалятор сухого порошка с активацией с помощью миниатюрного датчика давления Download PDFInfo
- Publication number
- EA036644B1 EA036644B1 EA201790478A EA201790478A EA036644B1 EA 036644 B1 EA036644 B1 EA 036644B1 EA 201790478 A EA201790478 A EA 201790478A EA 201790478 A EA201790478 A EA 201790478A EA 036644 B1 EA036644 B1 EA 036644B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pressure sensor
- barometric pressure
- sensor
- breathing
- inhaler
- Prior art date
Links
- 229940112141 dry powder inhaler Drugs 0.000 title claims abstract description 6
- 230000004913 activation Effects 0.000 title description 4
- 239000003814 drug Substances 0.000 claims abstract description 75
- 238000000034 method Methods 0.000 claims abstract description 46
- 230000004044 response Effects 0.000 claims abstract description 30
- 239000000843 powder Substances 0.000 claims abstract description 25
- 230000007246 mechanism Effects 0.000 claims abstract description 12
- 229940079593 drug Drugs 0.000 claims description 71
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 57
- 210000004072 lung Anatomy 0.000 claims description 38
- 230000003434 inspiratory effect Effects 0.000 claims description 30
- 238000005259 measurement Methods 0.000 claims description 16
- 230000008859 change Effects 0.000 claims description 11
- 238000012545 processing Methods 0.000 claims description 9
- 230000002618 waking effect Effects 0.000 claims description 5
- 230000002269 spontaneous effect Effects 0.000 abstract description 13
- 230000008569 process Effects 0.000 abstract description 4
- 239000000443 aerosol Substances 0.000 description 22
- 238000004891 communication Methods 0.000 description 11
- 238000012377 drug delivery Methods 0.000 description 10
- 238000005516 engineering process Methods 0.000 description 10
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 9
- 238000013459 approach Methods 0.000 description 8
- 230000008021 deposition Effects 0.000 description 8
- 238000001514 detection method Methods 0.000 description 7
- 238000012544 monitoring process Methods 0.000 description 7
- 238000012546 transfer Methods 0.000 description 7
- 238000011282 treatment Methods 0.000 description 7
- 201000003883 Cystic fibrosis Diseases 0.000 description 6
- 238000012937 correction Methods 0.000 description 6
- 208000006673 asthma Diseases 0.000 description 5
- 230000008901 benefit Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 230000000241 respiratory effect Effects 0.000 description 5
- 206010028980 Neoplasm Diseases 0.000 description 4
- 238000011109 contamination Methods 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 238000002663 nebulization Methods 0.000 description 3
- 239000006199 nebulizer Substances 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 125000006850 spacer group Chemical group 0.000 description 3
- 102100026992 Dermcidin Human genes 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000004590 computer program Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000010304 firing Methods 0.000 description 2
- 238000001595 flow curve Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 230000036387 respiratory rate Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 238000009423 ventilation Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 208000000884 Airway Obstruction Diseases 0.000 description 1
- 238000012935 Averaging Methods 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 102100038199 Desmoplakin Human genes 0.000 description 1
- 206010014561 Emphysema Diseases 0.000 description 1
- 206010038687 Respiratory distress Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000003190 augmentative effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 230000004199 lung function Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000013125 spirometry Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0036—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the breathing tube and used in both inspiratory and expiratory phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462043126P | 2014-08-28 | 2014-08-28 | |
| PCT/US2015/047365 WO2016033418A1 (en) | 2014-08-28 | 2015-08-28 | Tidal dry powder inhaler with miniature pressure sensor activation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201790478A1 EA201790478A1 (ru) | 2017-07-31 |
| EA036644B1 true EA036644B1 (ru) | 2020-12-03 |
Family
ID=54140659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201790478A EA036644B1 (ru) | 2014-08-28 | 2015-08-28 | Приводимый в действие спокойным дыханием ингалятор сухого порошка с активацией с помощью миниатюрного датчика давления |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10744283B2 (enExample) |
| EP (1) | EP3185939B1 (enExample) |
| JP (1) | JP6799529B2 (enExample) |
| KR (1) | KR20170047321A (enExample) |
| CN (1) | CN106687034B (enExample) |
| AR (1) | AR102056A1 (enExample) |
| AU (1) | AU2015308747B2 (enExample) |
| BR (1) | BR112017003867A2 (enExample) |
| CA (1) | CA2958891A1 (enExample) |
| EA (1) | EA036644B1 (enExample) |
| ES (1) | ES2824227T3 (enExample) |
| IL (1) | IL250749B (enExample) |
| MX (1) | MX2017002549A (enExample) |
| TW (1) | TW201618825A (enExample) |
| WO (1) | WO2016033418A1 (enExample) |
| ZA (1) | ZA201701046B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX388676B (es) | 2014-08-28 | 2025-03-20 | Norton Waterford Ltd | Modulo para ayuda de cumplimiento para un inhalador. |
| DK3463248T3 (da) * | 2016-05-27 | 2022-10-31 | Proveris Scient Corporation | Anordnnger til anvendelse af lægemiddelanordninger |
| GB201616036D0 (en) * | 2016-09-21 | 2016-11-02 | Nicoventures Holdings Ltd | Device with liquid flow restriction |
| WO2018064825A1 (zh) * | 2016-10-09 | 2018-04-12 | 益得生物科技股份有限公司 | 药物传递装置及其系统 |
| KR20190100907A (ko) * | 2016-10-11 | 2019-08-29 | 마이크로도스 테라퓨특스, 인코포레이티드 | 흡입기 및 그 사용 방법 |
| WO2018071445A1 (en) | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
| JP2020500632A (ja) * | 2016-12-09 | 2020-01-16 | マイクロドース セラピューテクス，インコーポレイテッド | 吸入器 |
| US11035704B2 (en) * | 2017-12-29 | 2021-06-15 | Altria Client Services Llc | Sensor apparatus |
| JP2021513901A (ja) * | 2018-02-23 | 2021-06-03 | マイクロドース セラピューテクス，インコーポレイテッド | 吸入器およびその使用方法 |
| EP3758603A4 (en) * | 2018-03-02 | 2021-12-01 | Singapore Health Services Pte Ltd | DEVICE AND METHOD FOR MEASURING RESPIRATORY AIR FLOW |
| US10953164B2 (en) * | 2018-03-05 | 2021-03-23 | Argospire Medical Inc. | Portable inhalation therapeutic and inhalation and exhalation measuring devices and related methods |
| AU2019261425B2 (en) * | 2018-04-24 | 2024-06-20 | Mannkind Corporation | Apparatus, system and method for detecting and monitoring inhalations |
| ES2807698B2 (es) * | 2019-08-23 | 2022-01-03 | Igncyerto S L | Dispositivo y metodo de medicion de dosis en inhaladores de polvo seco |
| CN115006656A (zh) * | 2022-05-18 | 2022-09-06 | 苏州易合医药有限公司 | 一种可连续提供肺部活性剂粉雾剂的给药装置 |
| CN120477747A (zh) * | 2025-07-16 | 2025-08-15 | 温州医科大学附属第一医院 | 一种肺功能评估方法、装置、电子设备及存储介质 |
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-
2015
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- 2015-08-28 EA EA201790478A patent/EA036644B1/ru not_active IP Right Cessation
- 2015-08-28 CA CA2958891A patent/CA2958891A1/en not_active Abandoned
- 2015-08-28 TW TW104128482A patent/TW201618825A/zh unknown
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2017
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| WO2016033418A1 (en) | 2016-03-03 |
| EA201790478A1 (ru) | 2017-07-31 |
| TW201618825A (zh) | 2016-06-01 |
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| CN106687034B (zh) | 2021-08-03 |
| EP3185939B1 (en) | 2020-09-30 |
| MX2017002549A (es) | 2017-05-25 |
| ES2824227T3 (es) | 2021-05-11 |
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| EP3185939A1 (en) | 2017-07-05 |
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| US10744283B2 (en) | 2020-08-18 |
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| US20170274162A1 (en) | 2017-09-28 |
| AU2015308747B2 (en) | 2019-12-19 |
| KR20170047321A (ko) | 2017-05-04 |
| BR112017003867A2 (pt) | 2018-11-06 |
| JP2017529151A (ja) | 2017-10-05 |
| ZA201701046B (en) | 2021-05-26 |
| IL250749B (en) | 2021-06-30 |
| CA2958891A1 (en) | 2016-03-03 |
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