EA035358B1 - Способ, набор и комбинация для лечения субъекта с симптомами инсульта или острого инфаркта миокарда - Google Patents
Способ, набор и комбинация для лечения субъекта с симптомами инсульта или острого инфаркта миокарда Download PDFInfo
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- EA035358B1 EA035358B1 EA201790969A EA201790969A EA035358B1 EA 035358 B1 EA035358 B1 EA 035358B1 EA 201790969 A EA201790969 A EA 201790969A EA 201790969 A EA201790969 A EA 201790969A EA 035358 B1 EA035358 B1 EA 035358B1
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
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- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
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- C12Y—ENZYMES
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US201462074374P | 2014-11-03 | 2014-11-03 | |
| PCT/US2015/058878 WO2016073514A2 (en) | 2014-11-03 | 2015-11-03 | Methods and compositions for safe and effective thrombolysis |
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| EA201790969A1 EA201790969A1 (ru) | 2017-11-30 |
| EA035358B1 true EA035358B1 (ru) | 2020-06-01 |
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| EP3215221B1 (en) | 2014-11-03 | 2020-02-26 | Thrombolytic Science, LLC | Methods and compositions for safe and effective thrombolysis |
| WO2018232305A1 (en) * | 2017-06-16 | 2018-12-20 | Thrombolytic Science, Llc | Methods and compositions for thrombolysis |
| CN107516010B (zh) * | 2017-08-19 | 2021-02-09 | 上海矩点医疗科技有限公司 | 溶栓剂量模型的构建方法 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0786257B1 (en) * | 1992-06-03 | 2003-07-30 | Genentech, Inc. | Tissue plasminogen activator glycosylation variants with improved therapeutic properties |
| US20070298024A1 (en) * | 2006-06-22 | 2007-12-27 | Thrombolytic Science, Inc. | C-1 inactivator inhibits two-chain urokinase mutant and limits hemostatic bleeding during thrombolysis |
| US20090226413A1 (en) * | 2003-04-18 | 2009-09-10 | Thrombolytic Science, Inc. | Methods, Devices, And Compositions For Lysis Of Occlusive Blood Clots While Sparing Wound Sealing Clots |
| US20100196348A1 (en) * | 2002-02-22 | 2010-08-05 | Paul Armstrong | COMBINATION TREATMENT WITH t-PA VARIANT AND LOW MOLECULAR WEIGHT HEPARIN |
| US20110229454A1 (en) * | 2008-03-31 | 2011-09-22 | Jianning Liu | Use of Prourokinase and Variants Thereof in Facilitated Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction |
| US20130244941A1 (en) * | 2005-12-21 | 2013-09-19 | Pharming Intellectual Property B.V. | Use Of C1 Inhibitor For The Prevention Of Ischemia-Reperfusion Injury |
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| US4381346A (en) | 1979-11-13 | 1983-04-26 | Huasin Syed S | Isolation of plasminogen activators useful as therapeutic and diagnostic agents |
| GB2197195B (en) | 1986-10-03 | 1991-01-23 | Sandoz Ltd | Improvments in or relating to organic compounds |
| GB8623823D0 (en) | 1986-10-03 | 1986-11-05 | Sandoz Ltd | Therapeutic lysis of fibrin blood clots |
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- 2015-11-03 EP EP15856204.1A patent/EP3215221B1/en active Active
- 2015-11-03 EA EA201790969A patent/EA035358B1/ru unknown
- 2015-11-03 EP EP20158876.1A patent/EP3708226A1/en not_active Withdrawn
- 2015-11-03 WO PCT/US2015/058878 patent/WO2016073514A2/en not_active Ceased
- 2015-11-03 CN CN201580058489.0A patent/CN107073292B/zh active Active
- 2015-11-03 JP JP2017543288A patent/JP6826040B2/ja active Active
- 2015-11-03 DK DK15856204.1T patent/DK3215221T3/da active
- 2015-11-03 MX MX2017005793A patent/MX383561B/es unknown
- 2015-11-03 CA CA2966332A patent/CA2966332C/en active Active
- 2015-11-03 ES ES15856204T patent/ES2788697T3/es active Active
- 2015-11-03 US US15/523,900 patent/US11213574B2/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3708226A1 (en) | 2020-09-16 |
| DK3215221T3 (da) | 2020-05-11 |
| JP6826040B2 (ja) | 2021-02-03 |
| CA2966332C (en) | 2024-04-16 |
| ES2788697T3 (es) | 2020-10-22 |
| WO2016073514A2 (en) | 2016-05-12 |
| US20220184189A1 (en) | 2022-06-16 |
| CA2966332A1 (en) | 2016-05-12 |
| EP3215221A4 (en) | 2018-08-08 |
| EA201790969A1 (ru) | 2017-11-30 |
| WO2016073514A3 (en) | 2016-08-11 |
| JP2017533961A (ja) | 2017-11-16 |
| BR112017008749A2 (pt) | 2017-12-19 |
| EP3215221B1 (en) | 2020-02-26 |
| US11213574B2 (en) | 2022-01-04 |
| EP3215221A2 (en) | 2017-09-13 |
| CN107073292A (zh) | 2017-08-18 |
| HK1243666A1 (en) | 2018-07-20 |
| CN107073292B (zh) | 2021-07-02 |
| MX2017005793A (es) | 2017-10-23 |
| MX383561B (es) | 2025-03-14 |
| US20180311322A1 (en) | 2018-11-01 |
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