EA034825B1 - Разовые высокие дозы mva индуцируют защитный иммунный ответ у новорожденных и младенцев - Google Patents
Разовые высокие дозы mva индуцируют защитный иммунный ответ у новорожденных и младенцев Download PDFInfo
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- EA034825B1 EA034825B1 EA201591803A EA201591803A EA034825B1 EA 034825 B1 EA034825 B1 EA 034825B1 EA 201591803 A EA201591803 A EA 201591803A EA 201591803 A EA201591803 A EA 201591803A EA 034825 B1 EA034825 B1 EA 034825B1
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- mva
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- mice
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- C12N2710/00011—Details
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- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Veterinary Medicine (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Molecular Biology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US201361788722P | 2013-03-15 | 2013-03-15 | |
| PCT/EP2014/000693 WO2014139687A1 (en) | 2013-03-15 | 2014-03-14 | Single high dose of mva induces a protective immune response in neonates and infants |
Publications (2)
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| EA201591803A1 EA201591803A1 (ru) | 2016-02-29 |
| EA034825B1 true EA034825B1 (ru) | 2020-03-25 |
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| EP (2) | EP2968524A1 (https=) |
| JP (1) | JP6480875B2 (https=) |
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| KR102269491B1 (ko) * | 2013-03-15 | 2021-06-25 | 버베리안 노딕 에이/에스 | 단회 고용량의 mva가 신생아 및 영아에서 보호 면역 반응을 유도 |
| US10653766B2 (en) | 2014-03-12 | 2020-05-19 | Bavarian Nordic A/S | Use of oil and water emulsions for increasing B cell responses with modified Vaccinia Ankara virus |
| EP4164682A1 (en) * | 2020-06-10 | 2023-04-19 | Bavarian Nordic A/S | A recombinant modified vaccinia virus ankara (mva) vaccine against coronavirus disease |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2003088994A2 (en) * | 2002-04-19 | 2003-10-30 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| WO2009152969A1 (en) * | 2008-06-20 | 2009-12-23 | Bavarian Nordic A/S | Recombinant modified vaccinia virus measles vaccine |
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| GB9117596D0 (en) * | 1991-08-15 | 1991-10-02 | John Gibson Lifting Gear Ltd | Pulling system |
| US5471902A (en) * | 1994-02-22 | 1995-12-05 | Athenry Enterprises Limited | Tuning system for pianos |
| US7628980B2 (en) * | 2000-11-23 | 2009-12-08 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| US7097842B2 (en) * | 2000-11-23 | 2006-08-29 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| US7445924B2 (en) * | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| UA76731C2 (uk) * | 2000-11-23 | 2006-09-15 | Баваріан Нордік А/С | Штам mva-bn модифікованого вірусу коров'ячої віспи ankara, фармацевтична композиція, вакцина, застосування mva-bn для приготування лікарського препарату та для приготування вакцини, спосіб введення гомологічної і/або гетерологічної послідовності нуклеїнової кислоти в клітини-мішені in vitro, спосіб одержання пептиду або білка, спосіб одержання mva-bn, клітина, набір для основної/бустерної імунізації |
| US7501127B2 (en) * | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
| UA100836C2 (ru) * | 2005-02-23 | 2013-02-11 | Бавариан Нордик А/С | Применение модифицированного вируса осповакцины анкара (mva) для быстрой индукции иммунитета против поксвирусных или других инфекционных агентов |
| EP2064351A1 (en) * | 2006-09-08 | 2009-06-03 | Bavarian Nordic A/S | Phenotypic and genotypic differences of mva strains |
| AU2010305030A1 (en) * | 2009-10-08 | 2012-05-10 | Bavarian Nordic A/S | Generation of a broad T-cell response in humans against HIV |
| US9463238B2 (en) * | 2011-12-09 | 2016-10-11 | Bavarian Nordic A/S | Recombinant poxvirus vector comprising tetanus toxin fragment C |
| WO2013189611A1 (en) * | 2012-06-22 | 2013-12-27 | Bavarian Nordic A/S | Poxviral vectors for low antibody response after a first priming immunization |
| KR102435054B1 (ko) * | 2012-08-01 | 2022-08-22 | 버베리안 노딕 에이/에스 | 재조합 변형된 백시니아 바이러스 앙카라(ankara) (mva) 호흡기 신시티알 바이러스(rsv) 백신 |
| KR102269491B1 (ko) * | 2013-03-15 | 2021-06-25 | 버베리안 노딕 에이/에스 | 단회 고용량의 mva가 신생아 및 영아에서 보호 면역 반응을 유도 |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003088994A2 (en) * | 2002-04-19 | 2003-10-30 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| WO2009152969A1 (en) * | 2008-06-20 | 2009-12-23 | Bavarian Nordic A/S | Recombinant modified vaccinia virus measles vaccine |
Non-Patent Citations (2)
| Title |
|---|
| "Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination (MVA(TB)029)", ClinicalTrials.gov 30 January 2013 (2013-01-30), XP002725419, Retrieved from the Internet: URL:http://clinicaltrials.gov/show/NCT0165 0389 [retrieved on 2014-06-04] the whole document * |
| WALSH STEPHEN R; WILCK MARISSA B; DOMINGUEZ DAVID J; ZABLOWSKY ELISE; BAJIMAYA SHRINGKHALA; GAGNE LISA S; VERRILL KELLY A; KLEINJA: "Safety and immunogenicity of modified vaccinia Ankara in hematopoietic stem cell transplant recipients: a randomized, controlled trial.", THE JOURNAL OF INFECTIOUS DISEASES, INFECTIOUS DISEASES SOCIETY OF AMERICA, US, vol. 207, no. 12, 15 June 2013 (2013-06-15), US, pages 1888 - 1897, XP009178362, ISSN: 1537-6613, DOI: 10.1093/infdis/jit105 * |
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| MX2015011388A (es) | 2016-02-03 |
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| AU2019200977A1 (en) | 2019-02-28 |
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| CA2905569C (en) | 2023-07-25 |
| IL241059B (en) | 2020-10-29 |
| SG11201507192SA (en) | 2015-10-29 |
| KR20150129027A (ko) | 2015-11-18 |
| HK1216860A1 (zh) | 2016-12-09 |
| CN105101993A (zh) | 2015-11-25 |
| US20160030551A1 (en) | 2016-02-04 |
| NZ711569A (en) | 2021-03-26 |
| SG10201707340XA (en) | 2017-10-30 |
| MY175269A (en) | 2020-06-17 |
| ZA201507017B (en) | 2018-12-19 |
| EA201591803A1 (ru) | 2016-02-29 |
| WO2014139687A1 (en) | 2014-09-18 |
| AU2022235527B2 (en) | 2023-10-26 |
| EP2968524A1 (en) | 2016-01-20 |
| UA126785C2 (uk) | 2023-02-08 |
| EP3708187A1 (en) | 2020-09-16 |
| US9707291B2 (en) | 2017-07-18 |
| AU2022235527A1 (en) | 2022-10-13 |
| AU2020260472A1 (en) | 2020-11-26 |
| KR102269491B1 (ko) | 2021-06-25 |
| AU2014231229A1 (en) | 2015-09-17 |
| BR112015021781A2 (pt) | 2017-07-18 |
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