EA030095B1 - Получение белка гемагглютинин-нейраминидазы в микроводорослях - Google Patents

Получение белка гемагглютинин-нейраминидазы в микроводорослях Download PDF

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Publication number
EA030095B1
EA030095B1 EA201290565A EA201290565A EA030095B1 EA 030095 B1 EA030095 B1 EA 030095B1 EA 201290565 A EA201290565 A EA 201290565A EA 201290565 A EA201290565 A EA 201290565A EA 030095 B1 EA030095 B1 EA 030095B1
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EA
Eurasian Patent Office
Prior art keywords
protein
polypeptide
bei
thb
membrane
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EA201290565A
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English (en)
Russian (ru)
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EA201290565A1 (ru
Inventor
Кирк Е. Эпт
Энн-Сесиль В. Бэйн
Джеймс Кейси Липмейер
Сюань Го
Джойс А. Притчард
Original Assignee
ДиЭсЭм АйПи АССЕТС Б.В.
Мериал Лимитед
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Publication of EA201290565A1 publication Critical patent/EA201290565A1/ru
Publication of EA030095B1 publication Critical patent/EA030095B1/ru

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01018Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18151Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18611Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18651Methods of production or purification of viral material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
EA201290565A 2009-12-28 2010-12-28 Получение белка гемагглютинин-нейраминидазы в микроводорослях EA030095B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29046909P 2009-12-28 2009-12-28
PCT/US2010/062274 WO2011082189A1 (en) 2009-12-28 2010-12-28 Production of hemagglutinin-neuraminidase protein in microalgae

Publications (2)

Publication Number Publication Date
EA201290565A1 EA201290565A1 (ru) 2013-02-28
EA030095B1 true EA030095B1 (ru) 2018-06-29

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EA201290565A EA030095B1 (ru) 2009-12-28 2010-12-28 Получение белка гемагглютинин-нейраминидазы в микроводорослях

Country Status (9)

Country Link
US (1) US9012197B2 (enExample)
EP (1) EP2519636B8 (enExample)
JP (1) JP5838473B2 (enExample)
CN (1) CN103068984B (enExample)
AU (1) AU2010339544B2 (enExample)
CA (1) CA2785867C (enExample)
EA (1) EA030095B1 (enExample)
IN (1) IN2012DN06278A (enExample)
WO (1) WO2011082189A1 (enExample)

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TWI504749B (zh) 2009-03-16 2015-10-21 Dsm Ip Assets Bv 於網黏菌門微生物中生產蛋白質之技術
AR079767A1 (es) * 2009-12-28 2012-02-15 Merial Ltd Antigeno ndv (virus de la enfermedad de newcastle) recombinante y usos del mismo
IN2012DN06277A (enExample) * 2009-12-28 2015-09-25 Dsm Ip Assets Bv
BR122015020119B8 (pt) 2010-01-19 2021-05-04 Dsm Ip Assets Bv óleo microbiano, produtos alimentícios para um animal não humano e biomassa isolada
WO2013013211A1 (en) * 2011-07-21 2013-01-24 Dsm Ip Assets B.V. Fatty acid compositions
CN103525785B (zh) * 2013-09-24 2015-03-25 西北大学 一种分离纯化神经氨酸酶(禽流感病毒)的方法
CA2977271A1 (en) 2015-03-02 2016-09-09 Synthetic Genomics, Inc. Regulatory elements from labyrinthulomycetes microorganisms
US10457970B2 (en) 2016-11-01 2019-10-29 Conagen Inc. Expression of modified glycoproteins and glycopeptides
US10633454B2 (en) 2016-11-01 2020-04-28 Conagen Inc. Expression of modified glycoproteins and glycopeptides
CN112074608A (zh) * 2018-05-01 2020-12-11 科纳根公司 用于产生具有高聚糖占有率的糖分子的重组生物体和方法
CA3239417A1 (en) 2021-11-30 2023-06-08 Yvonne CHAN Human metapneumovirus vaccines

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AR079767A1 (es) 2009-12-28 2012-02-15 Merial Ltd Antigeno ndv (virus de la enfermedad de newcastle) recombinante y usos del mismo
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Also Published As

Publication number Publication date
CA2785867C (en) 2018-03-27
CN103068984B (zh) 2017-12-01
EP2519636B8 (en) 2017-08-09
EP2519636A4 (en) 2013-07-03
AU2010339544A1 (en) 2012-08-09
US20110195480A1 (en) 2011-08-11
IN2012DN06278A (enExample) 2015-09-25
AU2010339544B2 (en) 2015-11-12
EP2519636B1 (en) 2017-03-01
CN103068984A (zh) 2013-04-24
CA2785867A1 (en) 2011-07-07
WO2011082189A1 (en) 2011-07-07
EP2519636A1 (en) 2012-11-07
EA201290565A1 (ru) 2013-02-28
US9012197B2 (en) 2015-04-21
JP2013515502A (ja) 2013-05-09
JP5838473B2 (ja) 2016-01-06

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