EA026453B1 - Применение окисленного авидина для ингаляции - Google Patents
Применение окисленного авидина для ингаляции Download PDFInfo
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- EA026453B1 EA026453B1 EA201490401A EA201490401A EA026453B1 EA 026453 B1 EA026453 B1 EA 026453B1 EA 201490401 A EA201490401 A EA 201490401A EA 201490401 A EA201490401 A EA 201490401A EA 026453 B1 EA026453 B1 EA 026453B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- inhalation
- biotinylated
- agent
- lungs
- oxidized avidin
- Prior art date
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- A61K9/0012—Galenical forms characterised by the site of application
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- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- A—HUMAN NECESSITIES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
- A61K47/665—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells the pre-targeting system, clearing therapy or rescue therapy involving biotin-(strept) avidin systems
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- A—HUMAN NECESSITIES
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11006338 | 2011-08-02 | ||
| PCT/EP2012/064576 WO2013017494A1 (en) | 2011-08-02 | 2012-07-25 | Pharmaceutical composition of oxidised avidin suitable for inhalation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201490401A1 EA201490401A1 (ru) | 2014-05-30 |
| EA026453B1 true EA026453B1 (ru) | 2017-04-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| EA201490401A EA026453B1 (ru) | 2011-08-02 | 2012-07-25 | Применение окисленного авидина для ингаляции |
Country Status (19)
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2941243A4 (en) | 2013-01-04 | 2016-09-14 | Massachusetts Inst Technology | SURFACE BINDING IN THE ADMINISTRATION OF A MEDICAMENT ON NANOPARTICLE BASE IN A TISSUE |
| EP3458097A4 (en) * | 2016-05-19 | 2020-01-08 | University of Miami | TARGETED DELIVERY OF THERAPEUTIC AGENTS AND IMAGING REAGENTS TO CANCER PANCREAS CELLS |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009016031A1 (en) * | 2007-08-02 | 2009-02-05 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Oxidized avidin with high residency time in the treated tissues |
| EP2106806A1 (en) * | 2008-03-31 | 2009-10-07 | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. | Nanoparticles for targeted delivery of active agents to the lung |
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| US5384128A (en) * | 1993-03-02 | 1995-01-24 | University Of Alabama Research Foundation | Method of and compounds for treatment for cystic fibrosis |
| WO1995003034A1 (en) | 1993-07-19 | 1995-02-02 | Amgen Inc. | Stabilization of aerosolized proteins |
| DE69830305T2 (de) * | 1997-02-20 | 2006-02-02 | Dime, David S., Toronto | Ortsspezifische arzneimittel verabreichung |
| EP1169053A1 (en) * | 1999-04-13 | 2002-01-09 | Inhale Therapeutic Systems, Inc. | Pulmonary administration of dry powder formulations for treating infertility |
| US7001994B2 (en) * | 2001-01-18 | 2006-02-21 | Genzyme Corporation | Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins |
| ITRM20010079A1 (it) | 2001-02-16 | 2002-08-16 | Sigma Tau Ind Farmaceuti | Amminoderivati della biotina e loro coniugati con chelanti macrociclici. |
| ITRM20030196A1 (it) * | 2003-04-24 | 2004-10-25 | Sigma Tau Ind Farmaceuti | Uso di reagenti per la preparazione di un medicamento |
| BRPI0517204A (pt) * | 2004-12-17 | 2008-09-30 | Cipla Ltd | sulfato de levosalbutamol cristalino (forma i), sulfato de levosalbutamol cristalino (forma ii), sulfato de levosalbutamol cristalino (forma iii), processo para preparar a forma i do sulfato de levosalbutamol cristalino, processo para preparar a forma ii do sulfato de levosalbutamol cristalino, processo para preparar a forma iii do sulfato de levosalbutamol, composição farmacêutica, composto, combinação, pó seco para inalador, processo para preparar um pó seco para inalador, processo para preparar uma composição famacêutica, processo para fabricação de uma composição farmacêutica, método para tratamento de um mamìfero, e uso de uma combinação de salbutamol |
| GB0602778D0 (en) * | 2006-02-10 | 2006-03-22 | Glaxo Group Ltd | Novel compound |
| TW201031436A (en) * | 2009-02-16 | 2010-09-01 | Univ Nat Taiwan | Pharmaceutical composition for inhalation delivery and fabrication method thereof |
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2012
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- 2012-07-25 PH PH1/2014/500193A patent/PH12014500193A1/en unknown
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009016031A1 (en) * | 2007-08-02 | 2009-02-05 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Oxidized avidin with high residency time in the treated tissues |
| EP2106806A1 (en) * | 2008-03-31 | 2009-10-07 | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. | Nanoparticles for targeted delivery of active agents to the lung |
Non-Patent Citations (1)
| Title |
|---|
| BOERMAN OTTO C ET AL: "Pretargeted radioimmunotherapy of cancer: Progress step by step.", THE JOURNAL OF NUCLEAR MEDICINE, SOCIETY OF NUCLEAR MEDICINE, US, vol. 44, no. 3, 1 March 2003 (2003-03-01), US, pages 400 - 411, XP002292436, ISSN: 0161-5505 * |
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| AU2012292229A1 (en) | 2014-02-13 |
| EP2739314B1 (en) | 2019-05-22 |
| WO2013017494A1 (en) | 2013-02-07 |
| PL2739314T3 (pl) | 2019-09-30 |
| UA114482C2 (uk) | 2017-06-26 |
| CA2842276A1 (en) | 2013-02-07 |
| CA2842276C (en) | 2020-11-24 |
| KR20140047668A (ko) | 2014-04-22 |
| MX2014001176A (es) | 2014-07-14 |
| US9872831B2 (en) | 2018-01-23 |
| EA201490401A1 (ru) | 2014-05-30 |
| AU2012292229B2 (en) | 2017-08-03 |
| JP6019118B2 (ja) | 2016-11-02 |
| DK2739314T3 (da) | 2019-06-24 |
| IL230597A0 (en) | 2014-03-31 |
| MX355177B (es) | 2018-04-09 |
| JP2014521675A (ja) | 2014-08-28 |
| PT2739314T (pt) | 2019-06-21 |
| BR112014002593A2 (pt) | 2017-03-01 |
| KR101966630B1 (ko) | 2019-04-09 |
| ES2729549T3 (es) | 2019-11-04 |
| ZA201401921B (en) | 2015-05-27 |
| BR112014002593B1 (pt) | 2022-11-29 |
| CN103717239B (zh) | 2017-08-01 |
| US20140134106A1 (en) | 2014-05-15 |
| CN103717239A (zh) | 2014-04-09 |
| PH12014500193A1 (en) | 2014-03-24 |
| NZ620202A (en) | 2016-05-27 |
| EP2739314A1 (en) | 2014-06-11 |
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