EA025780B1 - Цитокиновые биомаркеры в качестве биомаркеров, прогнозирующих клинический ответ на глатирамер ацетат - Google Patents
Цитокиновые биомаркеры в качестве биомаркеров, прогнозирующих клинический ответ на глатирамер ацетат Download PDFInfo
- Publication number
- EA025780B1 EA025780B1 EA201390543A EA201390543A EA025780B1 EA 025780 B1 EA025780 B1 EA 025780B1 EA 201390543 A EA201390543 A EA 201390543A EA 201390543 A EA201390543 A EA 201390543A EA 025780 B1 EA025780 B1 EA 025780B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- glatiramer acetate
- concentration
- human
- responding
- multiple sclerosis
- Prior art date
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| NZ598661A (en) | 2009-08-20 | 2013-02-22 | Yeda Res & Dev | Low frequency glatiramer acetate therapy |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| CA2814500A1 (en) | 2010-10-11 | 2012-04-19 | Teva Pharmaceutical Industries Ltd | Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate |
| HK1200274A1 (en) | 2011-10-10 | 2015-08-07 | Teva Pharmaceutical Industries Ltd. | Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate |
| HK1213830A1 (zh) * | 2012-10-10 | 2016-07-15 | Teva Pharmaceutical Industries Ltd. | 用於预测醋酸格拉替雷临床反应的生物标志物 |
| CN105377308B (zh) | 2013-03-14 | 2019-07-26 | 迈兰公司 | 醋酸格拉替雷响应生物标志物mRNA效力测定 |
| UY35790A (es) | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
| US9995734B2 (en) | 2013-10-24 | 2018-06-12 | Mylan Inc. | Human T cell line assay for evaluating the immunologic identity of glatiramer acetate preparations |
| US20160213633A1 (en) * | 2015-01-28 | 2016-07-28 | Teva Pharmaceutical Industries, Ltd. | Method of inducing anti-glatiramer acetate antibody response |
| US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| CN109982712A (zh) | 2016-08-31 | 2019-07-05 | Mapi医药公司 | 包含醋酸格拉替雷的储库系统 |
| CN110382052A (zh) | 2017-03-26 | 2019-10-25 | Mapi医药公司 | 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统 |
| EP3844501A1 (en) * | 2018-08-30 | 2021-07-07 | Essen Instruments, Inc. d/b/a Essen BioScience, Inc. | Methods for determining concentration of low and high concentration proteins in a single sample |
| WO2025181335A1 (en) * | 2024-02-29 | 2025-09-04 | Grifols Worldwide Operations Limited | Methods of treating a cognitive impairment |
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| US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
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Patent Citations (2)
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| US20100062471A1 (en) * | 2005-09-29 | 2010-03-11 | Ppd Biomarker Discovery Sciences Llc | Biomarkers for Multiple Sclerosis and Methods of Use Thereof |
| WO2007081975A2 (en) * | 2006-01-11 | 2007-07-19 | Teva Pharmaceutical Industries, Ltd. | Method of treating multiple sclerosis |
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| IL225118A (en) | 2017-10-31 |
| JP2016188214A (ja) | 2016-11-04 |
| EA201390543A1 (ru) | 2013-09-30 |
| US20150241446A1 (en) | 2015-08-27 |
| US20120121619A1 (en) | 2012-05-17 |
| NZ703122A (en) | 2016-06-24 |
| MX347871B (es) | 2017-05-16 |
| US9625473B2 (en) | 2017-04-18 |
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