EA025345B1 - Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и фармацевтические композиции для лечения заболевания, обусловленного hdac6, включающие эти соединения - Google Patents

Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и фармацевтические композиции для лечения заболевания, обусловленного hdac6, включающие эти соединения Download PDF

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Publication number
EA025345B1
EA025345B1 EA201390711A EA201390711A EA025345B1 EA 025345 B1 EA025345 B1 EA 025345B1 EA 201390711 A EA201390711 A EA 201390711A EA 201390711 A EA201390711 A EA 201390711A EA 025345 B1 EA025345 B1 EA 025345B1
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Eurasian Patent Office
Prior art keywords
compound
compounds
pharmaceutically acceptable
disease
cancer
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EA201390711A
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English (en)
Russian (ru)
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EA201390711A1 (ru
Inventor
Джон Х. Ван Дюзер
Ральф Мацичек
Янбинг Динг
Нань Юй
Юн Цао
Юн Лю
Original Assignee
Эситайлон Фармасьютикалз, Инк.
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Application filed by Эситайлон Фармасьютикалз, Инк. filed Critical Эситайлон Фармасьютикалз, Инк.
Publication of EA201390711A1 publication Critical patent/EA201390711A1/ru
Publication of EA025345B1 publication Critical patent/EA025345B1/ru

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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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EA201390711A 2010-11-16 2011-11-15 Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и фармацевтические композиции для лечения заболевания, обусловленного hdac6, включающие эти соединения EA025345B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41415810P 2010-11-16 2010-11-16
US201161503286P 2011-06-30 2011-06-30
PCT/US2011/060791 WO2012068109A2 (en) 2010-11-16 2011-11-15 Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof

Publications (2)

Publication Number Publication Date
EA201390711A1 EA201390711A1 (ru) 2014-03-31
EA025345B1 true EA025345B1 (ru) 2016-12-30

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EA201390711A EA025345B1 (ru) 2010-11-16 2011-11-15 Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и фармацевтические композиции для лечения заболевания, обусловленного hdac6, включающие эти соединения
EA201691121A EA201691121A1 (ru) 2010-11-16 2011-11-15 Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и способы их применения

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US (3) US8614223B2 (https=)
EP (2) EP3067346A1 (https=)
JP (2) JP6041808B2 (https=)
KR (1) KR20130115300A (https=)
CN (2) CN103429574B (https=)
AU (2) AU2011329028B2 (https=)
BR (1) BR112013011868A2 (https=)
CA (1) CA2818125A1 (https=)
CL (1) CL2013001381A1 (https=)
EA (2) EA025345B1 (https=)
ES (1) ES2568260T3 (https=)
IL (2) IL226326A0 (https=)
MX (1) MX2013005392A (https=)
NZ (2) NZ710405A (https=)
PH (2) PH12013500964A1 (https=)
PL (1) PL2640709T3 (https=)
PT (1) PT2640709T (https=)
SG (2) SG10201509324QA (https=)
WO (1) WO2012068109A2 (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2764718C2 (ru) * 2017-04-14 2022-01-19 Италфармако С.П.А. Селективные ингибиторы hdac6

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