EA025256B1 - Композиция, подходящая для лечения нарушений липидного обмена - Google Patents

Композиция, подходящая для лечения нарушений липидного обмена Download PDF

Info

Publication number
EA025256B1
EA025256B1 EA201391622A EA201391622A EA025256B1 EA 025256 B1 EA025256 B1 EA 025256B1 EA 201391622 A EA201391622 A EA 201391622A EA 201391622 A EA201391622 A EA 201391622A EA 025256 B1 EA025256 B1 EA 025256B1
Authority
EA
Eurasian Patent Office
Prior art keywords
dose
vitamin
acid
resveratrol
carnitine
Prior art date
Application number
EA201391622A
Other languages
English (en)
Russian (ru)
Other versions
EA201391622A1 (ru
Inventor
Алеардо Коверек
Ашраф Вирмани
Original Assignee
Сигма-Тау Индустрие Фармасьютике Риуните С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сигма-Тау Индустрие Фармасьютике Риуните С.П.А. filed Critical Сигма-Тау Индустрие Фармасьютике Риуните С.П.А.
Publication of EA201391622A1 publication Critical patent/EA201391622A1/ru
Publication of EA025256B1 publication Critical patent/EA025256B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EA201391622A 2011-05-03 2012-04-24 Композиция, подходящая для лечения нарушений липидного обмена EA025256B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11164526 2011-05-03
PCT/EP2012/057428 WO2012150146A1 (en) 2011-05-03 2012-04-24 Composition useful for the treatment of lipid metabolism disorders

Publications (2)

Publication Number Publication Date
EA201391622A1 EA201391622A1 (ru) 2014-02-28
EA025256B1 true EA025256B1 (ru) 2016-12-30

Family

ID=44645300

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201391622A EA025256B1 (ru) 2011-05-03 2012-04-24 Композиция, подходящая для лечения нарушений липидного обмена

Country Status (29)

Country Link
US (1) US9125903B2 (enExample)
EP (1) EP2704734B1 (enExample)
JP (1) JP2014514340A (enExample)
KR (1) KR101840082B1 (enExample)
CN (1) CN103517711B (enExample)
AR (1) AR086231A1 (enExample)
AU (1) AU2012251818B2 (enExample)
CA (1) CA2834173A1 (enExample)
CL (1) CL2013003144A1 (enExample)
CY (1) CY1116612T1 (enExample)
DK (1) DK2704734T3 (enExample)
EA (1) EA025256B1 (enExample)
ES (1) ES2542412T3 (enExample)
HR (1) HRP20150767T1 (enExample)
IL (1) IL229205A (enExample)
ME (1) ME02180B (enExample)
MX (1) MX361038B (enExample)
MY (1) MY176018A (enExample)
NZ (1) NZ617641A (enExample)
PH (1) PH12013502229A1 (enExample)
PL (1) PL2704734T3 (enExample)
PT (1) PT2704734E (enExample)
RS (1) RS54100B1 (enExample)
SG (1) SG194679A1 (enExample)
SI (1) SI2704734T1 (enExample)
SM (1) SMT201500173B (enExample)
UA (1) UA112182C2 (enExample)
WO (1) WO2012150146A1 (enExample)
ZA (1) ZA201309205B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103202471B (zh) * 2013-04-25 2014-06-11 福建永生活力生物工程有限公司 一种辅助降血脂的保健食品及其制备方法
WO2016193096A1 (en) 2015-05-29 2016-12-08 Givaudan Sa Spray drying
CN105395925A (zh) * 2015-11-27 2016-03-16 杭州海王生物工程有限公司 一种以降血脂为基础的具有降血压和减肥功效的组合物
CN105475580A (zh) * 2016-01-19 2016-04-13 苟春虎 黑青稞降血脂茶（奶茶）
CN105853347A (zh) * 2016-04-01 2016-08-17 海南合瑞制药股份有限公司 一种左卡尼汀的组合物及其制备方法
IT201600075378A1 (it) * 2016-07-19 2018-01-19 Farm Legnani Del Dottor De Zanetti Andrea Integratore alimentare a base di riso rosso fermentato
IT201600078969A1 (it) * 2016-07-27 2018-01-27 Buonamici Gugliemo Integratore alimentare
WO2019018937A1 (en) 2017-07-26 2019-01-31 Yacyshyn Vincent REMOVAL OF CONTAMINANT POLYPHENOLS FROM START LOAD POLYPHENOLS
EP3735296A4 (en) 2018-01-04 2021-09-08 Pure Care Pro Llc NATURAL COMBINED PRODUCTS AND TOTAL BLOOD CHOLESTEROL REGULATION METHODS
US11173187B2 (en) 2018-11-13 2021-11-16 Immortazyme Company Ltd. Concentrated oil-based polyphenol composition and a method of producing the oil-based polyphenol composition
IT201900007002A1 (it) * 2019-05-20 2020-11-20 Angelo Montecuollo Integratore alimentare a base di caffè
CN112056563A (zh) * 2020-09-15 2020-12-11 王胜林 用于修复脂质代谢障碍的营养素组合物及其应用
KR102418383B1 (ko) * 2020-11-19 2022-07-07 한국식품산업클러스터진흥원 천연 복합물을 포함하는 비만 예방 또는 치료용 조성물
IT202200003191A1 (it) * 2022-02-21 2023-08-21 Inpha Res S R L Composizione per il controllo delle iperlipidemie
CN119424573B (zh) * 2024-02-05 2025-09-26 天津铭瑞医药科技有限公司 用于治疗高脂血症的中西药物组合

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0780124A1 (en) * 1995-12-21 1997-06-25 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Pharmaceutical composition comprising L-carnitine or an alkanoyl L-carnitine in combination with a polyunsaturated fatty acid of the omega-3 series for the prevention and the treatment of lipid metabolism disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2903558C2 (de) * 1978-02-03 1994-09-01 Sigma Tau Ind Farmaceuti Verwendung von L-Carnitin
JP3926888B2 (ja) * 1997-05-27 2007-06-06 株式会社カネカ コレステロール低下剤
ITRM20030178A1 (it) 2003-04-17 2004-10-18 Sigma Tau Ind Farmaceuti Uso della l-carnitina per il trattamento di patologie cardiovascolari.
KR101573316B1 (ko) * 2004-03-29 2015-12-01 와이어쓰 엘엘씨 종합비타민 및 무기물 영양 보충제
US20100119600A1 (en) * 2007-06-01 2010-05-13 Joar Opheim Substances for reducing occurrence of major cardiac events comprising red yeast rice extract and omega-3 polyunsaturated fatty acid or derivative thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0780124A1 (en) * 1995-12-21 1997-06-25 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Pharmaceutical composition comprising L-carnitine or an alkanoyl L-carnitine in combination with a polyunsaturated fatty acid of the omega-3 series for the prevention and the treatment of lipid metabolism disorders

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BECKER DAVID J, ET AL: "Simvastatin vs therapeutic lifestyle changes and supplements: randomized primary prevention trial.", MAYO CLINIC PROCEEDINGS, DOWDEN HEALTH MEDIA, INC, US, vol. 83, no. 7, 1 July 2008 (2008-07-01), US, pages 758 - 764, XP002659882, ISSN: 0025-6196 *
HAN DONG HAO, LI REN HE: "Mechanisms of cardiovascular protection by resveratrol", JOURNAL OF MEDICINAL FOOD, MARY ANN LIEBERT, LARCHMONT, NY,, US, vol. 7, no. 3, 1 September 2004 (2004-09-01), US, pages 290 - 298, XP002659884, ISSN: 1096-620X, DOI: 10.1089/JMF.2004.7.290 *
KRISTA A. VARADY, YANWEN WANG, PETER J.H. JONES: "Role of policosanols in the prevention and treatment of cardiovascular disease.", NUTRITION REVIEWS., ALLEN PRESS, LAWRENCE, KS., US, vol. 61, no. 11, 1 November 2003 (2003-11-01), US, pages 376 - 383, XP002659883, ISSN: 0029-6643, DOI: 10.1301/NR.2003.NOV.376-383 *
SALVATORE PEPE, C, SILVANA F. MARASCO, C, STEVEN J. HAAS, FREYA L. SHEERAN, HENRY KRUM, FRANKLIN L. ROSENFELDT: "Coenzyme Q10 in cardiovascular disease", MITOCHONDRION, ELSEVIER, AMSTERDAM, NL, vol. 7, no. SUPPL., 1 June 2007 (2007-06-01), NL, pages S154 - S167, XP002659885, ISSN: 1567-7249, DOI: 10.1016/J.MITO.2007.02.005 *

Also Published As

Publication number Publication date
AU2012251818A1 (en) 2013-11-28
CL2013003144A1 (es) 2014-07-04
PH12013502229A1 (en) 2021-06-23
SI2704734T1 (sl) 2015-08-31
JP2014514340A (ja) 2014-06-19
NZ617641A (en) 2015-12-24
UA112182C2 (uk) 2016-08-10
CN103517711A (zh) 2014-01-15
HRP20150767T1 (hr) 2015-08-28
MY176018A (en) 2020-07-21
CA2834173A1 (en) 2012-11-08
SG194679A1 (en) 2013-12-30
IL229205A (en) 2017-01-31
EP2704734B1 (en) 2015-06-17
EA201391622A1 (ru) 2014-02-28
MX361038B (es) 2018-11-26
RS54100B1 (sr) 2015-10-30
ES2542412T3 (es) 2015-08-05
AU2012251818B2 (en) 2017-04-13
EP2704734A1 (en) 2014-03-12
PL2704734T3 (pl) 2015-10-30
AR086231A1 (es) 2013-11-27
KR20140036170A (ko) 2014-03-25
DK2704734T3 (en) 2015-07-20
US9125903B2 (en) 2015-09-08
CN103517711B (zh) 2016-07-27
IL229205A0 (en) 2014-01-30
PT2704734E (pt) 2015-09-07
CY1116612T1 (el) 2017-03-15
US20140086985A1 (en) 2014-03-27
SMT201500173B (it) 2015-10-30
WO2012150146A1 (en) 2012-11-08
MX2013012781A (es) 2013-12-06
ME02180B (me) 2015-10-20
ZA201309205B (en) 2015-04-29
KR101840082B1 (ko) 2018-03-19

Similar Documents

Publication Publication Date Title
EA025256B1 (ru) Композиция, подходящая для лечения нарушений липидного обмена
EP1983989B1 (en) Combinations of botanical extracts for promoting cardiovascular health
JP6092843B2 (ja) 神経障害の治療用組成物
US5211956A (en) Pharmaceutical compositions containing phytic acid or its salts
US20090252817A1 (en) Methods for the treatment or prevention of Diabetes Mellitus and other metabolic imbalances
KR20070058460A (ko) 스타틴 및 오메가 3 지방산 함유 조성물
WO2001087291A1 (fr) Compositions permettant de regulariser le rythme circadien
AU2007237685A1 (en) Compositions containing riboflavin and sesamin-class compounds
JP2021078397A (ja) 脂質減少促進剤
CN105120857B (zh) 营养组合物
WO2023223943A1 (ja) 血管内皮機能改善用組成物
TW201300119A (zh) 用於治療脂質代謝失調之組成物
HK1188933A (en) Composition useful for the treatment of lipid metabolism disorders
HK40089161A (zh) 烟醯胺腺嘌呤二核苷酸(nad)浓度上升剂
HK1188933B (en) Composition useful for the treatment of lipid metabolism disorders
JP2002238499A (ja) 高トリグリセリド血症治療剤
WO2020040216A1 (ja) 深部体温低下剤、食品、睡眠改善剤
JPWO2001087291A1 (ja) 日内リズム正常化組成物
HK1194665B (en) Compositions for the treatment of neurologic disorders
NZ616554B2 (en) Compositions for the treatment of neurologic disorders

Legal Events

Date Code Title Description
PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY KZ MD