CY1116612T1 - Συνθεση χρησιμη για τη θεραπευτικη αντιμετωπιση διαταραχων στο λιπιδικο μεταβολισμο - Google Patents

Συνθεση χρησιμη για τη θεραπευτικη αντιμετωπιση διαταραχων στο λιπιδικο μεταβολισμο

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Publication number
CY1116612T1
CY1116612T1 CY20151100624T CY151100624T CY1116612T1 CY 1116612 T1 CY1116612 T1 CY 1116612T1 CY 20151100624 T CY20151100624 T CY 20151100624T CY 151100624 T CY151100624 T CY 151100624T CY 1116612 T1 CY1116612 T1 CY 1116612T1
Authority
CY
Cyprus
Prior art keywords
treatment
lipid metabolism
composite useful
polycosanol
active substances
Prior art date
Application number
CY20151100624T
Other languages
English (en)
Inventor
Aleardo Koverech
Ashraf Virmani
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of CY1116612T1 publication Critical patent/CY1116612T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota

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  • Engineering & Computer Science (AREA)
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  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
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  • Obesity (AREA)
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Abstract

Η παρούσα εφεύρεση αναφέρεται σε μια σύνθεση χρήσιμη για την θεραπευτική αντιμετώπιση διαταραχών στο λιπιδικό μεταβολισμό, που περιλαμβάνει μια ή περισσότερες από τις ακόλουθες δραστικές ουσίες: (α) εκχύλισμα ρυζιού ζυμωμένο με Monascus purpureus, (β) ένα τουλάχιστον ωμέγα-3 λιπαρό οξύ, (γ) L-καρνιτίνη ή ένα άλας αυτής• και μια ή περισσότερες από τις ακόλουθες δραστικές ουσίες: (δ) μια τουλάχιστον πολυκοζανόλη ή ένα φυσικό εκχύλισμα που περιέχει πολυκοζανόλες• (ε) ρεσβερατρόλη ή ένα φυσικό εκχύλισμα που περιέχει ρεσβερατρόλη• (στ) συνένζυμο Q10• και (ζ) μια τουλάχιστον βιταμίνη.
CY20151100624T 2011-05-03 2015-07-17 Συνθεση χρησιμη για τη θεραπευτικη αντιμετωπιση διαταραχων στο λιπιδικο μεταβολισμο CY1116612T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11164526 2011-05-03
EP12716038.0A EP2704734B1 (en) 2011-05-03 2012-04-24 Composition useful for the treatment of lipid metabolism disorders

Publications (1)

Publication Number Publication Date
CY1116612T1 true CY1116612T1 (el) 2017-03-15

Family

ID=44645300

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20151100624T CY1116612T1 (el) 2011-05-03 2015-07-17 Συνθεση χρησιμη για τη θεραπευτικη αντιμετωπιση διαταραχων στο λιπιδικο μεταβολισμο

Country Status (28)

Country Link
US (1) US9125903B2 (el)
EP (1) EP2704734B1 (el)
JP (1) JP2014514340A (el)
KR (1) KR101840082B1 (el)
CN (1) CN103517711B (el)
AR (1) AR086231A1 (el)
AU (1) AU2012251818B2 (el)
CA (1) CA2834173A1 (el)
CL (1) CL2013003144A1 (el)
CY (1) CY1116612T1 (el)
DK (1) DK2704734T3 (el)
EA (1) EA025256B1 (el)
ES (1) ES2542412T3 (el)
HR (1) HRP20150767T1 (el)
IL (1) IL229205A (el)
ME (1) ME02180B (el)
MX (1) MX361038B (el)
MY (1) MY176018A (el)
NZ (1) NZ617641A (el)
PL (1) PL2704734T3 (el)
PT (1) PT2704734E (el)
RS (1) RS54100B1 (el)
SG (1) SG194679A1 (el)
SI (1) SI2704734T1 (el)
SM (1) SMT201500173B (el)
UA (1) UA112182C2 (el)
WO (1) WO2012150146A1 (el)
ZA (1) ZA201309205B (el)

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CN103202471B (zh) * 2013-04-25 2014-06-11 福建永生活力生物工程有限公司 一种辅助降血脂的保健食品及其制备方法
US10384185B2 (en) 2015-05-29 2019-08-20 Givaudan S.A. Spray drying
CN105395925A (zh) * 2015-11-27 2016-03-16 杭州海王生物工程有限公司 一种以降血脂为基础的具有降血压和减肥功效的组合物
CN105475580A (zh) * 2016-01-19 2016-04-13 苟春虎 黑青稞降血脂茶（奶茶）
CN105853347A (zh) * 2016-04-01 2016-08-17 海南合瑞制药股份有限公司 一种左卡尼汀的组合物及其制备方法
IT201600075378A1 (it) * 2016-07-19 2018-01-19 Farm Legnani Del Dottor De Zanetti Andrea Integratore alimentare a base di riso rosso fermentato
IT201600078969A1 (it) * 2016-07-27 2018-01-27 Buonamici Gugliemo Integratore alimentare
EP3638801A4 (en) 2017-07-26 2021-03-24 Yacyshyn, Vincent DISPOSAL OF POLYPHENOLS CONTAMINANTS FROM STARTING CHARGE POLYPHENOLS
EP3735296A4 (en) * 2018-01-04 2021-09-08 Pure Care Pro Llc NATURAL COMBINED PRODUCTS AND TOTAL BLOOD CHOLESTEROL REGULATION METHODS
US11173187B2 (en) 2018-11-13 2021-11-16 Immortazyme Company Ltd. Concentrated oil-based polyphenol composition and a method of producing the oil-based polyphenol composition
IT201900007002A1 (it) * 2019-05-20 2020-11-20 Angelo Montecuollo Integratore alimentare a base di caffè
CN112056563A (zh) * 2020-09-15 2020-12-11 王胜林 用于修复脂质代谢障碍的营养素组合物及其应用
KR102418383B1 (ko) * 2020-11-19 2022-07-07 한국식품산업클러스터진흥원 천연 복합물을 포함하는 비만 예방 또는 치료용 조성물
IT202200003191A1 (it) * 2022-02-21 2023-08-21 Inpha Res S R L Composizione per il controllo delle iperlipidemie

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DE2903558C2 (de) 1978-02-03 1994-09-01 Sigma Tau Ind Farmaceuti Verwendung von L-Carnitin
IT1277953B1 (it) 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
JP3926888B2 (ja) * 1997-05-27 2007-06-06 株式会社カネカ コレステロール低下剤
ITRM20030178A1 (it) 2003-04-17 2004-10-18 Sigma Tau Ind Farmaceuti Uso della l-carnitina per il trattamento di patologie cardiovascolari.
CA2794424C (en) * 2004-03-29 2019-06-04 Wyeth Llc Multi-vitamin and mineral nutritional supplements
US20100119600A1 (en) * 2007-06-01 2010-05-13 Joar Opheim Substances for reducing occurrence of major cardiac events comprising red yeast rice extract and omega-3 polyunsaturated fatty acid or derivative thereof

Also Published As

Publication number Publication date
US20140086985A1 (en) 2014-03-27
CN103517711B (zh) 2016-07-27
CA2834173A1 (en) 2012-11-08
NZ617641A (en) 2015-12-24
CN103517711A (zh) 2014-01-15
MY176018A (en) 2020-07-21
AR086231A1 (es) 2013-11-27
KR20140036170A (ko) 2014-03-25
ZA201309205B (en) 2015-04-29
SI2704734T1 (sl) 2015-08-31
MX361038B (es) 2018-11-26
IL229205A0 (en) 2014-01-30
ME02180B (me) 2015-10-20
PT2704734E (pt) 2015-09-07
JP2014514340A (ja) 2014-06-19
HRP20150767T1 (hr) 2015-08-28
CL2013003144A1 (es) 2014-07-04
DK2704734T3 (en) 2015-07-20
RS54100B1 (en) 2015-10-30
EA025256B1 (ru) 2016-12-30
WO2012150146A1 (en) 2012-11-08
UA112182C2 (uk) 2016-08-10
KR101840082B1 (ko) 2018-03-19
PL2704734T3 (pl) 2015-10-30
AU2012251818A1 (en) 2013-11-28
IL229205A (en) 2017-01-31
AU2012251818B2 (en) 2017-04-13
MX2013012781A (es) 2013-12-06
EP2704734B1 (en) 2015-06-17
EP2704734A1 (en) 2014-03-12
SMT201500173B (it) 2015-10-30
SG194679A1 (en) 2013-12-30
ES2542412T3 (es) 2015-08-05
US9125903B2 (en) 2015-09-08
EA201391622A1 (ru) 2014-02-28

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