BR112012032816A2 - composição farmacêutica de liberação controlada, e, métodos para reduzir o efeito alimentar de uma composição de liberação controlada, reduzir o período de tempo necessário para que seja alcançado um estado estável para a metformina, para aperfeiçoar a biodisponibilidade de uma forma de dosagem de liberação controlada de matriz - Google Patents

composição farmacêutica de liberação controlada, e, métodos para reduzir o efeito alimentar de uma composição de liberação controlada, reduzir o período de tempo necessário para que seja alcançado um estado estável para a metformina, para aperfeiçoar a biodisponibilidade de uma forma de dosagem de liberação controlada de matriz

Info

Publication number
BR112012032816A2
BR112012032816A2 BR112012032816A BR112012032816A BR112012032816A2 BR 112012032816 A2 BR112012032816 A2 BR 112012032816A2 BR 112012032816 A BR112012032816 A BR 112012032816A BR 112012032816 A BR112012032816 A BR 112012032816A BR 112012032816 A2 BR112012032816 A2 BR 112012032816A2
Authority
BR
Brazil
Prior art keywords
controlled release
reducing
composition
pharmaceutical composition
metformin
Prior art date
Application number
BR112012032816A
Other languages
English (en)
Inventor
Chaur-Ming Jan
Shao-Ming Lee
Shou-Chiung
Original Assignee
Twi Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Twi Pharmaceuticals filed Critical Twi Pharmaceuticals
Publication of BR112012032816A2 publication Critical patent/BR112012032816A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds

Abstract

composição farmacêutica de liberação controlada, e, métodos para reduzir o efeito alimentar de uma composição de liberação controlada, reduzir o período de tempo necessário para que seja alcançado um estado estável para a metformina, para aperfeiçoar a biodisponibilidade de uma forma de dosagem de liberação controlada de matriz. a presente invenção provê uma composição farmacêutica de liberação controlada, que exibe um efeito alimentar reduzido.
BR112012032816A 2010-06-22 2011-06-21 composição farmacêutica de liberação controlada, e, métodos para reduzir o efeito alimentar de uma composição de liberação controlada, reduzir o período de tempo necessário para que seja alcançado um estado estável para a metformina, para aperfeiçoar a biodisponibilidade de uma forma de dosagem de liberação controlada de matriz BR112012032816A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35725110P 2010-06-22 2010-06-22
PCT/US2011/041218 WO2011163206A2 (en) 2010-06-22 2011-06-21 Controlled release compositions with reduced food effect

Publications (1)

Publication Number Publication Date
BR112012032816A2 true BR112012032816A2 (pt) 2016-11-08

Family

ID=45328888

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012032816A BR112012032816A2 (pt) 2010-06-22 2011-06-21 composição farmacêutica de liberação controlada, e, métodos para reduzir o efeito alimentar de uma composição de liberação controlada, reduzir o período de tempo necessário para que seja alcançado um estado estável para a metformina, para aperfeiçoar a biodisponibilidade de uma forma de dosagem de liberação controlada de matriz

Country Status (13)

Country Link
US (1) US8486453B2 (pt)
EP (1) EP2585052A4 (pt)
JP (1) JP2013533241A (pt)
KR (1) KR20140007247A (pt)
CN (1) CN103037849A (pt)
AR (1) AR084698A1 (pt)
AU (1) AU2011271124A1 (pt)
BR (1) BR112012032816A2 (pt)
CA (1) CA2802335A1 (pt)
MX (1) MX2012015188A (pt)
RU (1) RU2012155890A (pt)
TW (1) TW201206503A (pt)
WO (1) WO2011163206A2 (pt)

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Also Published As

Publication number Publication date
JP2013533241A (ja) 2013-08-22
RU2012155890A (ru) 2014-07-27
EP2585052A2 (en) 2013-05-01
CA2802335A1 (en) 2011-12-29
CN103037849A (zh) 2013-04-10
US20110311594A1 (en) 2011-12-22
MX2012015188A (es) 2013-05-20
AU2011271124A1 (en) 2013-01-10
WO2011163206A2 (en) 2011-12-29
KR20140007247A (ko) 2014-01-17
WO2011163206A4 (en) 2012-04-26
EP2585052A4 (en) 2014-10-01
AR084698A1 (es) 2013-06-05
US8486453B2 (en) 2013-07-16
TW201206503A (en) 2012-02-16
WO2011163206A3 (en) 2012-03-01

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]