EA201200210A1 - Состав, содержащий производное витамина k3 и нестероидный противовоспалительный препарат - Google Patents

Состав, содержащий производное витамина k3 и нестероидный противовоспалительный препарат

Info

Publication number
EA201200210A1
EA201200210A1 EA201200210A EA201200210A EA201200210A1 EA 201200210 A1 EA201200210 A1 EA 201200210A1 EA 201200210 A EA201200210 A EA 201200210A EA 201200210 A EA201200210 A EA 201200210A EA 201200210 A1 EA201200210 A1 EA 201200210A1
Authority
EA
Eurasian Patent Office
Prior art keywords
vitamin
composition containing
inflammatory drug
steroid anti
containing derivative
Prior art date
Application number
EA201200210A
Other languages
English (en)
Inventor
Штеффен Кнапп
Александир Либ
Камяб Амузегар
Original Assignee
Лонца Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лонца Лтд. filed Critical Лонца Лтд.
Publication of EA201200210A1 publication Critical patent/EA201200210A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/132Heterocyclic compounds containing only one nitrogen as hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • A23K40/10Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • A23K40/30Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)

Abstract

В заявке описаны высоко стабилизированные частицы, содержащие никотинамид (НА) и производное витамина K3, при этом никотинамид образует физический защитный слой (как непрерывный, так и прерывистый), обеспечивающий высокую стабильность частиц производного витамина K3, а также способ его получения.
EA201200210A 2009-08-05 2010-08-03 Состав, содержащий производное витамина k3 и нестероидный противовоспалительный препарат EA201200210A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23138009P 2009-08-05 2009-08-05
EP09010104A EP2281465A1 (en) 2009-08-05 2009-08-05 Vitamin K3 derivative / NSA formulation
PCT/EP2010/004729 WO2011015334A2 (en) 2009-08-05 2010-08-03 Vitamin k3 derivative/nsa formulation

Publications (1)

Publication Number Publication Date
EA201200210A1 true EA201200210A1 (ru) 2012-09-28

Family

ID=41131667

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201200210A EA201200210A1 (ru) 2009-08-05 2010-08-03 Состав, содержащий производное витамина k3 и нестероидный противовоспалительный препарат

Country Status (8)

Country Link
US (1) US20110045089A1 (ru)
EP (2) EP2281465A1 (ru)
JP (1) JP2013500730A (ru)
CN (1) CN102480996A (ru)
BR (1) BR112012002678A2 (ru)
CA (1) CA2770033A1 (ru)
EA (1) EA201200210A1 (ru)
WO (1) WO2011015334A2 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104163779B (zh) * 2014-06-06 2016-04-13 浙江工业大学 一种管式连续化制备亚硫酸氢钠甲萘醌的方法
US9364483B2 (en) * 2014-06-20 2016-06-14 Laboratorios Virbac Pre-mix composition for cattle
US10757485B2 (en) 2017-08-25 2020-08-25 Honda Motor Co., Ltd. System and method for synchronized vehicle sensor data acquisition processing using vehicular communication
US11181929B2 (en) 2018-07-31 2021-11-23 Honda Motor Co., Ltd. System and method for shared autonomy through cooperative sensing
US11163317B2 (en) 2018-07-31 2021-11-02 Honda Motor Co., Ltd. System and method for shared autonomy through cooperative sensing

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2808361A (en) * 1955-03-09 1957-10-01 Russell R Bavouset Solubilizer for preparing an aqueous soluble menadione
US3196018A (en) * 1960-08-08 1965-07-20 Galler William Coated menadione bisulfite adduct
NL143128B (nl) 1962-11-09 1974-09-16 Randstad Chem Ind Werkwijze voor het bereiden van een zout van een organische base en menadionbisulfiet, alsmede werkwijze ter bereiding van een veterinair preparaat onder toepassing van een aldus bereid zout.
IT1097391B (it) * 1978-07-21 1985-08-31 Stoppani Luigi Spa Addotti di composti vitaminici del tipo k e vitamine stabilizzanti,loro preparazione e addotti stabilizzati cosi' ottenuti
JPS58206505A (ja) * 1982-05-25 1983-12-01 Mikasa Kagaku Kogyo Kk 魚毒性を軽減した除草剤組成物
DE3443270A1 (de) * 1984-11-28 1986-05-28 Basf Ag, 6700 Ludwigshafen Menadioncholinbisulfit-addukt und verfahren zu dessen herstellung
DE3700812A1 (de) * 1987-01-14 1988-07-28 Basf Ag Stabilisierte menadionbisulfit-formulierungen und verfahren zu deren herstellung
CN1040282C (zh) * 1993-01-07 1998-10-21 中国农业科学院饲料研究所 水可弥散脂溶性维生素饲料添加剂及其生产方法
US7632518B2 (en) * 2002-01-15 2009-12-15 Dsm Ip Assets B.V. 25-hydroxy vitamin D3 compositions
US20050092969A1 (en) * 2003-10-08 2005-05-05 Kaneka Corporation Method of stabilizing compound having quinone skeleton and stabilized composition
CN1650857A (zh) * 2004-12-07 2005-08-10 武汉新华扬生物有限责任公司 维生素c的包被方法
ZA200803025B (en) * 2005-10-12 2010-07-28 Genencor Int Stable, durable granules with active agents
CN101245038B (zh) * 2008-03-11 2010-07-28 山东轻工业学院 一种维生素k3的生产方法

Also Published As

Publication number Publication date
CN102480996A (zh) 2012-05-30
EP2281465A1 (en) 2011-02-09
CA2770033A1 (en) 2011-02-10
WO2011015334A2 (en) 2011-02-10
WO2011015334A3 (en) 2011-05-05
JP2013500730A (ja) 2013-01-10
EP2461699A2 (en) 2012-06-13
BR112012002678A2 (pt) 2015-09-01
US20110045089A1 (en) 2011-02-24

Similar Documents

Publication Publication Date Title
CY1116987T1 (el) Συμπυκνωμενα ιμιδαζολυλιμιδαζολια ως αντιϊικες ενωσεις
BR112015000106A2 (pt) moduladores heterocíclicos de síntes de lipídio
DK2282994T3 (da) 3-aminocarbazolforbindelse, farmaceutisk sammensætning indeholdende forbindelsen samt fremstillingsmetode derfor
EP2418200A4 (en) PHTHALIAMIDE DERIVATIVES FROM NON-SERIOUS ANTI-INFLAMMATORY COMPOUNDS AND / OR TNF MODULATORS, METHOD OF MANUFACTURING THEREOF, PHARMACEUTICAL COMPOSITIONS THEREFOR AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY DISEASES
ECSP13012668A (es) Ácidos 1-bencilcicloalquilcarboxílicos sustituidos y su uso
EA201170772A1 (ru) Органические соединения
UA107951C2 (en) Imidazopyridine derivatives as inhibitors of jak
CO6741203A2 (es) Derivados de biciclo[3,2,1]octilamida y sus usos
EA201201677A1 (ru) Производные гетероарилимидазолона в качестве ингибиторов jak
DK2411395T3 (da) Furopyrimidindionderivater som modulatorer for TRPA1
UY33075A (es) Derivados de ciclohexano y usos de los mismos
EA201290416A1 (ru) Новые спиропиперидиновые соединения
EA201892050A1 (ru) Способ получения замещенных 5-фтор-1h-пиразолопиридинов
CR11684A (es) Dihidropirazolonas sustituidas de hif-propil-4- como inhibidores hidroxilasa
EA201200616A1 (ru) Производные 2-оксо-1-пирролидинилимидазотиадиазола
EA201200471A1 (ru) Простые эфирные производные бициклических гетероарилов
ECSP11010992A (es) Derivados de anilina-pirimidina sustituidos con sulfoximina como inhibidores de quinasas dependientes de ciclina (cdk), producción y uso de los mismos como productos medicinales
CL2012003523A1 (es) Método para la preparación de una composición farmacéutica que contiene un portador de oxígeno termoestable; composicion farmaceutica que contiene un portador de oxigeno altamente purificado y termoestable.
EA201491818A1 (ru) Способ получения оптически чистых и необязательно замещенных производных 2-(1-гидроксиалкил)хромен-4-она и их применение при получении лекарственных препаратов
EA201290077A1 (ru) Соединения-801
EA201200210A1 (ru) Состав, содержащий производное витамина k3 и нестероидный противовоспалительный препарат
UA112764C2 (uk) Оптимізований синтез чистих, неполіморфних кристалічних жовчних кислот із заданим розміром частинок
EA201291097A1 (ru) Финголимод в форме гранулированного расплава
WO2010080414A3 (en) Substituted fno (2-[furan-2-yl] naphthalen-1-ol) derivatives as anti-cancer agents
EA201270176A1 (ru) Производные тазаротена