EA024873B1 - Терапевтическое средство при дислипидемии - Google Patents
Терапевтическое средство при дислипидемии Download PDFInfo
- Publication number
- EA024873B1 EA024873B1 EA201590653A EA201590653A EA024873B1 EA 024873 B1 EA024873 B1 EA 024873B1 EA 201590653 A EA201590653 A EA 201590653A EA 201590653 A EA201590653 A EA 201590653A EA 024873 B1 EA024873 B1 EA 024873B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- group
- compound
- pharmaceutical composition
- salt
- cholesterol
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| KR20200024165A (ko) * | 2017-06-30 | 2020-03-06 | 교와 가부시키가이샤 | 의약 조성물 |
| WO2019004448A1 (ja) * | 2017-06-30 | 2019-01-03 | 興和株式会社 | 医薬組成物 |
| JPWO2019004452A1 (ja) * | 2017-06-30 | 2020-04-30 | 興和株式会社 | 医薬組成物 |
| US11344535B2 (en) | 2017-06-30 | 2022-05-31 | Kowa Company, Ltd. | Pharmaceutical composition |
| JPWO2019004453A1 (ja) * | 2017-06-30 | 2020-04-30 | 興和株式会社 | 医薬品 |
| HUE069648T2 (hu) * | 2017-06-30 | 2025-03-28 | Kowa Co | Gyógyszerészeti készítmény |
| EP3646864B1 (en) | 2017-06-30 | 2026-04-08 | Kowa Company, Ltd. | Pharmaceutical containing pemafibrate |
| JP7425603B2 (ja) * | 2017-06-30 | 2024-01-31 | 興和株式会社 | 医薬組成物 |
| US11446282B2 (en) | 2017-12-21 | 2022-09-20 | Kowa Company, Ltd. | Methods of treating mixed dyslipidemia and hypertriglycertdemia |
| US20190224169A1 (en) * | 2017-12-21 | 2019-07-25 | Kowa Company, Ltd. | Methods of Treatment of Hypertriglyceridemia |
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| WO2008120472A1 (ja) * | 2007-03-29 | 2008-10-09 | Kowa Company, Ltd. | 高脂血症の予防及び／又は治療剤 |
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| HU230253B1 (hu) | 2001-01-26 | 2015-11-30 | Merck Sharp & Dohme Corp | Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére |
| US7205321B2 (en) | 2001-11-15 | 2007-04-17 | Eli Lilly And Company | Peroxisome proliferator activated receptor alpha agonists |
| US6987118B2 (en) | 2003-05-21 | 2006-01-17 | Pfizer Inc. | Tetrahydroisoquinoline derivatives as PPAR-alpha activators |
| WO2005009942A1 (ja) | 2003-07-28 | 2005-02-03 | Kyorin Pharmaceutical Co., Ltd. | 光学活性置換フェニルプロピオン酸誘導体 |
| CN100425594C (zh) * | 2003-09-03 | 2008-10-15 | 兴和株式会社 | Ppar活性化化合物及含该化合物的医药组合物 |
| DE102004016845A1 (de) | 2004-04-07 | 2005-10-27 | Bayer Healthcare Ag | Phenylthioessigsäure-Derivate und ihre Verwendung |
| US7629372B2 (en) | 2004-09-16 | 2009-12-08 | Merck & Co., Inc. | Compounds for the treatment of dyslipidemia and other lipid disorders |
| TWI359810B (en) | 2004-11-04 | 2012-03-11 | Mitsubishi Tanabe Pharma Corp | Carboxylic acid derivative containing thiazole rin |
| WO2007008529A2 (en) | 2005-07-08 | 2007-01-18 | Kalypsys, Inc | Celullar cholesterol absorption modifiers |
| WO2007008541A2 (en) | 2005-07-08 | 2007-01-18 | Kalypsys, Inc. | Cellular cholesterol absorption modifiers |
| US7795291B2 (en) | 2006-07-07 | 2010-09-14 | Bristol-Myers Squibb Company | Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method |
| CA2663502A1 (en) | 2006-09-15 | 2008-03-20 | Schering Corporation | Azetidinone derivatives and methods of use thereof |
| WO2008104875A1 (en) | 2007-03-01 | 2008-09-04 | Pfizer Products Inc. | Oxazolidinones as cholesterol absorption inhibitors |
| WO2009047240A1 (en) | 2007-10-09 | 2009-04-16 | Smithkline Beecham Corporation | Indole derivatives useful as ppar activators |
| DE102007061757A1 (de) | 2007-12-20 | 2009-06-25 | Bayer Healthcare Ag | Substituierte 2-Phenylpyrimidin-5-carbonsäuren und ihre Verwendung |
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2013
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- 2013-09-27 PL PL13842381T patent/PL2902025T3/pl unknown
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| WO2005023777A1 (ja) * | 2003-09-03 | 2005-03-17 | Kowa Co., Ltd. | Ppar活性化化合物及びこれを含有する医薬組成物 |
| WO2008120472A1 (ja) * | 2007-03-29 | 2008-10-09 | Kowa Company, Ltd. | 高脂血症の予防及び／又は治療剤 |
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