IN2015DN02966A - - Google Patents

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Publication number
IN2015DN02966A
IN2015DN02966A IN2966DEN2015A IN2015DN02966A IN 2015DN02966 A IN2015DN02966 A IN 2015DN02966A IN 2966DEN2015 A IN2966DEN2015 A IN 2966DEN2015A IN 2015DN02966 A IN2015DN02966 A IN 2015DN02966A
Authority
IN
India
Prior art keywords
prevention
treatment
formula
dyslipidemia
hypercholesterolemia
Prior art date
Application number
Inventor
Takizawa Toshiaki
Yoshinaka Yasunobu
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co filed Critical Kowa Co
Publication of IN2015DN02966A publication Critical patent/IN2015DN02966A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/423Oxazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The present invention addresses the problem of providing a pharmaceutical combination composition and drug combinations for the prevention and/or treatment of dyslipidemic conditions such as atherosclerosis , hypercholesterolemia , low HDL blood disease in mammals including humans. A pharmaceutical composition for the prevention and/or treatment of dyslipidemia , etc. which comprises (a) a compound represented by general formula (1) (in the formula each symbol is the same as defined in the specification) or a salt thereof or a solvate thereof and (b) a cholesterol absorption inhibitor. (1)
IN2966DEN2015 2012-09-27 2013-09-27 IN2015DN02966A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012214635 2012-09-27
PCT/JP2013/005756 WO2014050134A1 (en) 2012-09-27 2013-09-27 Therapeutic agent for dyslipidemia

Publications (1)

Publication Number Publication Date
IN2015DN02966A true IN2015DN02966A (en) 2015-09-18

Family

ID=50387566

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2966DEN2015 IN2015DN02966A (en) 2012-09-27 2013-09-27

Country Status (21)

Country Link
US (4) US9572798B2 (en)
EP (1) EP2902025B1 (en)
JP (1) JP6238460B2 (en)
KR (1) KR102098032B1 (en)
CN (1) CN104640544B (en)
AU (1) AU2013321918B2 (en)
BR (1) BR112015006305B1 (en)
CA (1) CA2901650C (en)
EA (1) EA024873B1 (en)
ES (1) ES2752039T3 (en)
HK (1) HK1206620A1 (en)
IL (1) IL237981B (en)
IN (1) IN2015DN02966A (en)
MX (1) MX357446B (en)
MY (1) MY177686A (en)
PH (1) PH12015500471A1 (en)
PL (1) PL2902025T3 (en)
PT (1) PT2902025T (en)
SG (1) SG11201501740XA (en)
TW (1) TWI598098B (en)
WO (1) WO2014050134A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI691331B (en) * 2014-09-26 2020-04-21 日商興和股份有限公司 A treating agent for dyslipidemia
JP7007379B2 (en) * 2017-06-30 2022-02-10 興和株式会社 Pharmaceutical composition
JP7104039B2 (en) * 2017-06-30 2022-07-20 興和株式会社 Pharmaceutical composition
CN110809470A (en) * 2017-06-30 2020-02-18 兴和株式会社 Pharmaceutical products
JPWO2019004447A1 (en) * 2017-06-30 2020-04-30 興和株式会社 Pharmaceutical composition
WO2019004452A1 (en) * 2017-06-30 2019-01-03 興和株式会社 Pharmaceutical composition
US11759456B2 (en) * 2017-06-30 2023-09-19 Kowa Company, Ltd. Pharmaceutical composition
EP3646864A4 (en) 2017-06-30 2021-03-17 Kowa Company, Ltd. Pharmaceutical containing pemafibrate
US20200129483A1 (en) * 2017-06-30 2020-04-30 Kowa Company, Ltd. Pharmaceutical composition
WO2019126597A1 (en) * 2017-12-21 2019-06-27 Kowa Company, Ltd. Methods of treatment of hypertrigl yceridemia
US11446282B2 (en) 2017-12-21 2022-09-20 Kowa Company, Ltd. Methods of treating mixed dyslipidemia and hypertriglycertdemia
WO2020138406A1 (en) * 2018-12-27 2020-07-02 興和株式会社 Pharmaceutical composition

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1413331T3 (en) 2001-01-26 2007-12-10 Schering Corp Combinations of the peroxisome proliferator-activated receptor (PPAR) activator fenofibrate and the sterol absorption inhibitor ezetimibe for vascular indications
US7205321B2 (en) 2001-11-15 2007-04-17 Eli Lilly And Company Peroxisome proliferator activated receptor alpha agonists
US6987118B2 (en) 2003-05-21 2006-01-17 Pfizer Inc. Tetrahydroisoquinoline derivatives as PPAR-alpha activators
JPWO2005009942A1 (en) 2003-07-28 2006-09-07 杏林製薬株式会社 Optically active substituted phenylpropionic acid derivatives
BRPI0413991B8 (en) * 2003-09-03 2021-05-25 Kowa Co ppar activator compound and pharmaceutical composition containing the same
CN100425594C (en) * 2003-09-03 2008-10-15 兴和株式会社 PPAR-activating compound and pharmaceutical composition comprising the compound
DE102004016845A1 (en) 2004-04-07 2005-10-27 Bayer Healthcare Ag Phenylthioacetic acid derivatives and their use
JP2008513458A (en) 2004-09-16 2008-05-01 メルク エンド カムパニー インコーポレーテッド Compounds for the treatment of dyslipidemia and other lipid disorders
TWI359810B (en) 2004-11-04 2012-03-11 Mitsubishi Tanabe Pharma Corp Carboxylic acid derivative containing thiazole rin
WO2007008541A2 (en) 2005-07-08 2007-01-18 Kalypsys, Inc. Cellular cholesterol absorption modifiers
WO2007008529A2 (en) 2005-07-08 2007-01-18 Kalypsys, Inc Celullar cholesterol absorption modifiers
US7795291B2 (en) 2006-07-07 2010-09-14 Bristol-Myers Squibb Company Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
MX2009002921A (en) 2006-09-15 2009-04-01 Schering Corp Azetidinone derivatives for the treatment of disorders of the lipid metabolism.
WO2008104875A1 (en) 2007-03-01 2008-09-04 Pfizer Products Inc. Oxazolidinones as cholesterol absorption inhibitors
TWI407955B (en) * 2007-03-29 2013-09-11 Kowa Co A preventive and/or therapeutical agent of hyperlipemia
WO2009047240A1 (en) 2007-10-09 2009-04-16 Smithkline Beecham Corporation Indole derivatives useful as ppar activators
DE102007061757A1 (en) 2007-12-20 2009-06-25 Bayer Healthcare Ag Substituted 2-phenylpyrimidine-5-carboxylic acids and their use

Also Published As

Publication number Publication date
MX357446B (en) 2018-07-10
TWI598098B (en) 2017-09-11
BR112015006305A2 (en) 2017-07-04
WO2014050134A1 (en) 2014-04-03
KR102098032B1 (en) 2020-04-07
KR20150063035A (en) 2015-06-08
AU2013321918A1 (en) 2015-04-23
EP2902025A1 (en) 2015-08-05
EA201590653A1 (en) 2015-07-30
US10258609B2 (en) 2019-04-16
SG11201501740XA (en) 2015-04-29
EA024873B1 (en) 2016-10-31
ES2752039T3 (en) 2020-04-02
PL2902025T3 (en) 2020-03-31
MX2015003705A (en) 2015-06-10
TW201417811A (en) 2014-05-16
AU2013321918B2 (en) 2018-05-10
PH12015500471B1 (en) 2015-04-20
MY177686A (en) 2020-09-23
CN104640544A (en) 2015-05-20
US20190167645A1 (en) 2019-06-06
IL237981A0 (en) 2015-05-31
CA2901650C (en) 2021-05-04
US20170112811A1 (en) 2017-04-27
US20150196538A1 (en) 2015-07-16
US9572798B2 (en) 2017-02-21
US11013722B2 (en) 2021-05-25
EP2902025B1 (en) 2019-08-07
HK1206620A1 (en) 2016-01-15
US20180185337A1 (en) 2018-07-05
US9931321B2 (en) 2018-04-03
JPWO2014050134A1 (en) 2016-08-22
BR112015006305B1 (en) 2020-11-17
PH12015500471A1 (en) 2015-04-20
JP6238460B2 (en) 2017-11-29
IL237981B (en) 2020-05-31
PT2902025T (en) 2019-11-04
EP2902025A4 (en) 2016-03-02
CA2901650A1 (en) 2014-04-03
CN104640544B (en) 2017-05-03

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