EA021102B1 - Температурочувствительный вакцинный штамм mycoplasma hyopneumoniae и его применения - Google Patents

Температурочувствительный вакцинный штамм mycoplasma hyopneumoniae и его применения Download PDF

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Publication number
EA021102B1
EA021102B1 EA201190311A EA201190311A EA021102B1 EA 021102 B1 EA021102 B1 EA 021102B1 EA 201190311 A EA201190311 A EA 201190311A EA 201190311 A EA201190311 A EA 201190311A EA 021102 B1 EA021102 B1 EA 021102B1
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EA
Eurasian Patent Office
Prior art keywords
vaccine
strain
vaccine composition
musoracta
pig
Prior art date
Application number
EA201190311A
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English (en)
Russian (ru)
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EA201190311A1 (ru
Inventor
Рима Юйль
Юссеф Абс Эль-Оста
Гленн Браунинг
Филлип Маркхэм
Original Assignee
Байопропертис Пти Лтд.
Де Юниверсити Оф Мельбурн
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Priority claimed from AU2009902255A external-priority patent/AU2009902255A0/en
Application filed by Байопропертис Пти Лтд., Де Юниверсити Оф Мельбурн filed Critical Байопропертис Пти Лтд.
Publication of EA201190311A1 publication Critical patent/EA201190311A1/ru
Publication of EA021102B1 publication Critical patent/EA021102B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0241Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36Adaptation or attenuation of cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/35Mycoplasma
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/87Mycoplasma

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
EA201190311A 2009-05-19 2010-05-19 Температурочувствительный вакцинный штамм mycoplasma hyopneumoniae и его применения EA021102B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2009902255A AU2009902255A0 (en) 2009-05-19 Bacterial strain, vaccine and uses thereof
PCT/AU2010/000590 WO2010132932A1 (en) 2009-05-19 2010-05-19 A temperature sensitive vaccine strain of mycoplasma hyopneumoniae and uses thereof

Publications (2)

Publication Number Publication Date
EA201190311A1 EA201190311A1 (ru) 2012-06-29
EA021102B1 true EA021102B1 (ru) 2015-04-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA201190311A EA021102B1 (ru) 2009-05-19 2010-05-19 Температурочувствительный вакцинный штамм mycoplasma hyopneumoniae и его применения

Country Status (17)

Country Link
US (1) US8524252B2 (enExample)
EP (1) EP2453913B1 (enExample)
JP (1) JP5744852B2 (enExample)
KR (1) KR101734590B1 (enExample)
CN (1) CN102458462B (enExample)
AU (1) AU2010251761B2 (enExample)
BR (1) BRPI1010679B1 (enExample)
CA (1) CA2762587C (enExample)
CL (1) CL2011002923A1 (enExample)
DK (1) DK2453913T3 (enExample)
EA (1) EA021102B1 (enExample)
ES (1) ES2579935T3 (enExample)
MX (1) MX2011012362A (enExample)
NZ (1) NZ596722A (enExample)
PE (1) PE20120909A1 (enExample)
WO (1) WO2010132932A1 (enExample)
ZA (1) ZA201109185B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9260691B2 (en) 2010-05-19 2016-02-16 Bioproperties Pty Ltd Methods relating to an attenuated mycoplasma
CN104685057B (zh) * 2012-07-10 2019-04-16 海博莱科学有限公司 用于转化猪肺炎支原体的载体,转化的猪肺炎支原体菌株及其用途
EP2684959A1 (en) * 2012-07-10 2014-01-15 Laboratorios Hipra, S.A. Vectors for transforming Mycoplasma hyopneumoniae, transformed M.hyopneumoniae strains, and use thereof
UA121193C2 (uk) 2012-12-28 2020-04-27 Бьорінгер Інгельхайм Ветмедіка Гмбх Спосіб одержання імуногенної композиції проти мікоплазми
US9878027B2 (en) 2012-12-28 2018-01-30 Boehringer Ingelheim Vetmedica Gmbh Immunogenic composition comprising mycoplasma antigens
EP2913947B1 (en) * 2014-02-27 2019-11-27 ADVA Optical Networking SE Passive optical network and optical line terminal
KR20160099223A (ko) * 2015-02-12 2016-08-22 강원대학교산학협력단 마이코플라스마 하이오뉴모니애 박테린 백신 및 이의 제조방법
US10071149B2 (en) 2016-05-03 2018-09-11 Brigham Young University Temperature sensitive multivalent Bordetella avium vaccines
CN113278575B (zh) * 2021-07-13 2021-12-31 南华大学 一种肺炎支原体减毒突变株及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010343A2 (en) * 2000-07-27 2002-02-07 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for mycoplasma hyopneumoniae

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN178995A0 (en) * 1995-03-16 1995-04-13 University Of Melbourne, The Antigen composition
CN1100871C (zh) * 1999-06-25 2003-02-05 江苏省农业科学院畜牧兽医研究所 猪肺炎支原体克隆致弱株
US6673567B2 (en) * 2000-03-23 2004-01-06 E. I. Du Pont De Nemours And Company Method of determination of gene function
MY129765A (en) * 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
WO2003004051A2 (en) * 2001-07-02 2003-01-16 Pfizer Products Inc. Mycoplasma hyopneumoniae vaccine and methods for reducing mycoplasma bovis pneumonia in cattle
US7691368B2 (en) * 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
MX2008011247A (es) * 2006-03-03 2008-09-11 Merial Ltd Vacuna de micoplasma hyopneumoniae.
ME01000B (me) * 2007-11-06 2012-10-20 Zoetis Services Llc Živa vakcina avirulentne mycoplasma hyopneumoniae sa adjuvansom
CN107213461B (zh) * 2009-09-10 2022-03-15 勃林格殷格翰动物保健美国公司 包含含有皂苷的佐剂的新疫苗制剂
US9324223B2 (en) 2012-06-08 2016-04-26 3M Innovative Properties Company Electronic monitoring home unit and installation methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010343A2 (en) * 2000-07-27 2002-02-07 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for mycoplasma hyopneumoniae

Also Published As

Publication number Publication date
CA2762587A1 (en) 2010-11-25
PE20120909A1 (es) 2012-08-19
AU2010251761A1 (en) 2011-12-22
DK2453913T3 (en) 2016-07-25
ZA201109185B (en) 2012-09-26
KR101734590B1 (ko) 2017-05-11
BRPI1010679B1 (pt) 2020-09-24
EP2453913B1 (en) 2016-06-22
US20120135040A1 (en) 2012-05-31
US8524252B2 (en) 2013-09-03
KR20120016282A (ko) 2012-02-23
NZ596722A (en) 2013-08-30
EP2453913A1 (en) 2012-05-23
EP2453913A4 (en) 2013-10-30
CN102458462B (zh) 2014-03-19
AU2010251761B2 (en) 2014-10-09
WO2010132932A1 (en) 2010-11-25
CN102458462A (zh) 2012-05-16
JP5744852B2 (ja) 2015-07-08
ES2579935T3 (es) 2016-08-17
JP2012527218A (ja) 2012-11-08
CL2011002923A1 (es) 2012-08-31
MX2011012362A (es) 2012-04-19
EA201190311A1 (ru) 2012-06-29
CA2762587C (en) 2017-11-28
BRPI1010679A2 (pt) 2017-07-18

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