AU2010251761B2 - A temperature sensitive vaccine strain of Mycoplasma hyopneumoniae and uses thereof - Google Patents

A temperature sensitive vaccine strain of Mycoplasma hyopneumoniae and uses thereof Download PDF

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Publication number
AU2010251761B2
AU2010251761B2 AU2010251761A AU2010251761A AU2010251761B2 AU 2010251761 B2 AU2010251761 B2 AU 2010251761B2 AU 2010251761 A AU2010251761 A AU 2010251761A AU 2010251761 A AU2010251761 A AU 2010251761A AU 2010251761 B2 AU2010251761 B2 AU 2010251761B2
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AU
Australia
Prior art keywords
putative
vaccine
protein
mycoplasma hyopneumoniae
strain
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AU2010251761A
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AU2010251761A1 (en
Inventor
Youssef Abs El-Osta
Glenn Browning
Phillip Markham
Rima Youil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Melbourne
Bioproperties Pty Ltd
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University of Melbourne
Bioproperties Pty Ltd
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Priority claimed from AU2009902255A external-priority patent/AU2009902255A0/en
Application filed by University of Melbourne, Bioproperties Pty Ltd filed Critical University of Melbourne
Priority to AU2010251761A priority Critical patent/AU2010251761B2/en
Publication of AU2010251761A1 publication Critical patent/AU2010251761A1/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/35—Mycoplasma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/87—Mycoplasma

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
AU2010251761A 2009-05-19 2010-05-19 A temperature sensitive vaccine strain of Mycoplasma hyopneumoniae and uses thereof Active AU2010251761B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010251761A AU2010251761B2 (en) 2009-05-19 2010-05-19 A temperature sensitive vaccine strain of Mycoplasma hyopneumoniae and uses thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2009902255A AU2009902255A0 (en) 2009-05-19 Bacterial strain, vaccine and uses thereof
AU2009902255 2009-05-19
AU2010251761A AU2010251761B2 (en) 2009-05-19 2010-05-19 A temperature sensitive vaccine strain of Mycoplasma hyopneumoniae and uses thereof
PCT/AU2010/000590 WO2010132932A1 (en) 2009-05-19 2010-05-19 A temperature sensitive vaccine strain of mycoplasma hyopneumoniae and uses thereof

Publications (2)

Publication Number Publication Date
AU2010251761A1 AU2010251761A1 (en) 2011-12-22
AU2010251761B2 true AU2010251761B2 (en) 2014-10-09

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Family Applications (1)

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AU2010251761A Active AU2010251761B2 (en) 2009-05-19 2010-05-19 A temperature sensitive vaccine strain of Mycoplasma hyopneumoniae and uses thereof

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US (1) US8524252B2 (enExample)
EP (1) EP2453913B1 (enExample)
JP (1) JP5744852B2 (enExample)
KR (1) KR101734590B1 (enExample)
CN (1) CN102458462B (enExample)
AU (1) AU2010251761B2 (enExample)
BR (1) BRPI1010679B1 (enExample)
CA (1) CA2762587C (enExample)
CL (1) CL2011002923A1 (enExample)
DK (1) DK2453913T3 (enExample)
EA (1) EA021102B1 (enExample)
ES (1) ES2579935T3 (enExample)
MX (1) MX2011012362A (enExample)
NZ (1) NZ596722A (enExample)
PE (1) PE20120909A1 (enExample)
WO (1) WO2010132932A1 (enExample)
ZA (1) ZA201109185B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9260691B2 (en) 2010-05-19 2016-02-16 Bioproperties Pty Ltd Methods relating to an attenuated mycoplasma
CN104685057B (zh) * 2012-07-10 2019-04-16 海博莱科学有限公司 用于转化猪肺炎支原体的载体，转化的猪肺炎支原体菌株及其用途
EP2684959A1 (en) * 2012-07-10 2014-01-15 Laboratorios Hipra, S.A. Vectors for transforming Mycoplasma hyopneumoniae, transformed M.hyopneumoniae strains, and use thereof
UA121193C2 (uk) 2012-12-28 2020-04-27 Бьорінгер Інгельхайм Ветмедіка Гмбх Спосіб одержання імуногенної композиції проти мікоплазми
US9878027B2 (en) 2012-12-28 2018-01-30 Boehringer Ingelheim Vetmedica Gmbh Immunogenic composition comprising mycoplasma antigens
EP2913947B1 (en) * 2014-02-27 2019-11-27 ADVA Optical Networking SE Passive optical network and optical line terminal
KR20160099223A (ko) * 2015-02-12 2016-08-22 강원대학교산학협력단 마이코플라스마 하이오뉴모니애 박테린 백신 및 이의 제조방법
US10071149B2 (en) 2016-05-03 2018-09-11 Brigham Young University Temperature sensitive multivalent Bordetella avium vaccines
CN113278575B (zh) * 2021-07-13 2021-12-31 南华大学 一种肺炎支原体减毒突变株及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010343A2 (en) * 2000-07-27 2002-02-07 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for mycoplasma hyopneumoniae

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN178995A0 (en) * 1995-03-16 1995-04-13 University Of Melbourne, The Antigen composition
CN1100871C (zh) * 1999-06-25 2003-02-05 江苏省农业科学院畜牧兽医研究所 猪肺炎支原体克隆致弱株
US6673567B2 (en) * 2000-03-23 2004-01-06 E. I. Du Pont De Nemours And Company Method of determination of gene function
MY129765A (en) * 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
WO2003004051A2 (en) * 2001-07-02 2003-01-16 Pfizer Products Inc. Mycoplasma hyopneumoniae vaccine and methods for reducing mycoplasma bovis pneumonia in cattle
US7691368B2 (en) * 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
MX2008011247A (es) * 2006-03-03 2008-09-11 Merial Ltd Vacuna de micoplasma hyopneumoniae.
ME01000B (me) * 2007-11-06 2012-10-20 Zoetis Services Llc Živa vakcina avirulentne mycoplasma hyopneumoniae sa adjuvansom
CN107213461B (zh) * 2009-09-10 2022-03-15 勃林格殷格翰动物保健美国公司 包含含有皂苷的佐剂的新疫苗制剂
US9324223B2 (en) 2012-06-08 2016-04-26 3M Innovative Properties Company Electronic monitoring home unit and installation methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010343A2 (en) * 2000-07-27 2002-02-07 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for mycoplasma hyopneumoniae
US6585981B1 (en) * 2000-07-27 2003-07-01 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for Mycoplasma hyopneumoniae

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LE CORROU J., et al, "Persistance of Mycoplasma hyopneumoniae in experimentally infected pigs after Marbofloxacin treatment and detection of mutations in the parC gene", Antimicrobial agents and chemotherapy, 2006, vol 50, pages 1959-1966 *

Also Published As

Publication number Publication date
CA2762587A1 (en) 2010-11-25
PE20120909A1 (es) 2012-08-19
AU2010251761A1 (en) 2011-12-22
DK2453913T3 (en) 2016-07-25
ZA201109185B (en) 2012-09-26
KR101734590B1 (ko) 2017-05-11
BRPI1010679B1 (pt) 2020-09-24
EP2453913B1 (en) 2016-06-22
US20120135040A1 (en) 2012-05-31
US8524252B2 (en) 2013-09-03
KR20120016282A (ko) 2012-02-23
NZ596722A (en) 2013-08-30
EP2453913A1 (en) 2012-05-23
EP2453913A4 (en) 2013-10-30
EA021102B1 (ru) 2015-04-30
CN102458462B (zh) 2014-03-19
WO2010132932A1 (en) 2010-11-25
CN102458462A (zh) 2012-05-16
JP5744852B2 (ja) 2015-07-08
ES2579935T3 (es) 2016-08-17
JP2012527218A (ja) 2012-11-08
CL2011002923A1 (es) 2012-08-31
MX2011012362A (es) 2012-04-19
EA201190311A1 (ru) 2012-06-29
CA2762587C (en) 2017-11-28
BRPI1010679A2 (pt) 2017-07-18

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