EA201190311A1 - Температурочувствительный вакцинный штамм mycoplasma hyopneumoniae и его применения - Google Patents

Температурочувствительный вакцинный штамм mycoplasma hyopneumoniae и его применения

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Publication number
EA201190311A1
EA201190311A1 EA201190311A EA201190311A EA201190311A1 EA 201190311 A1 EA201190311 A1 EA 201190311A1 EA 201190311 A EA201190311 A EA 201190311A EA 201190311 A EA201190311 A EA 201190311A EA 201190311 A1 EA201190311 A1 EA 201190311A1
Authority
EA
Eurasian Patent Office
Prior art keywords
applications
temperature
mycoplasma hyopneumoniae
vaccine strain
sensitive
Prior art date
Application number
EA201190311A
Other languages
English (en)
Other versions
EA021102B1 (ru
Inventor
Рима Юйль
Юссеф Абс Эль-Оста
Гленн Браунинг
Филлип Маркхэм
Original Assignee
Байопропертис Пти Лтд.
Де Юниверсити Оф Мельбурн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009902255A external-priority patent/AU2009902255A0/en
Application filed by Байопропертис Пти Лтд., Де Юниверсити Оф Мельбурн filed Critical Байопропертис Пти Лтд.
Publication of EA201190311A1 publication Critical patent/EA201190311A1/ru
Publication of EA021102B1 publication Critical patent/EA021102B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/35—Mycoplasma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/87—Mycoplasma

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Изобретение относится к вакцинному штамму Mycoplasma hyopneumoniae, содержащему мутацию по меньшей мере в одном из перечисленных генов, либо депонированному в Национальном институте измерений (Австралия) под регистрационным номером NM04/41259, который является температурочувствительным и аттенуированным, к вакцине, содержащей такие штаммы, и к способам и его применениям.
EA201190311A 2009-05-19 2010-05-19 Температурочувствительный вакцинный штамм mycoplasma hyopneumoniae и его применения EA021102B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2009902255A AU2009902255A0 (en) 2009-05-19 Bacterial strain, vaccine and uses thereof
PCT/AU2010/000590 WO2010132932A1 (en) 2009-05-19 2010-05-19 A temperature sensitive vaccine strain of mycoplasma hyopneumoniae and uses thereof

Publications (2)

Publication Number Publication Date
EA201190311A1 true EA201190311A1 (ru) 2012-06-29
EA021102B1 EA021102B1 (ru) 2015-04-30

Family

ID=43125658

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201190311A EA021102B1 (ru) 2009-05-19 2010-05-19 Температурочувствительный вакцинный штамм mycoplasma hyopneumoniae и его применения

Country Status (17)

Country Link
US (1) US8524252B2 (ru)
EP (1) EP2453913B1 (ru)
JP (1) JP5744852B2 (ru)
KR (1) KR101734590B1 (ru)
CN (1) CN102458462B (ru)
AU (1) AU2010251761B2 (ru)
BR (1) BRPI1010679B1 (ru)
CA (1) CA2762587C (ru)
CL (1) CL2011002923A1 (ru)
DK (1) DK2453913T3 (ru)
EA (1) EA021102B1 (ru)
ES (1) ES2579935T3 (ru)
MX (1) MX2011012362A (ru)
NZ (1) NZ596722A (ru)
PE (1) PE20120909A1 (ru)
WO (1) WO2010132932A1 (ru)
ZA (1) ZA201109185B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012013409A (es) * 2010-05-19 2013-03-07 Bioproperties Pty Ltd Metodos relacionados a un micoplasma atenuado.
CN104685057B (zh) * 2012-07-10 2019-04-16 海博莱科学有限公司 用于转化猪肺炎支原体的载体，转化的猪肺炎支原体菌株及其用途
EP2684959A1 (en) * 2012-07-10 2014-01-15 Laboratorios Hipra, S.A. Vectors for transforming Mycoplasma hyopneumoniae, transformed M.hyopneumoniae strains, and use thereof
WO2014105671A1 (en) 2012-12-28 2014-07-03 Boehringer Ingelheim Vetmedica Gmbh Immunogenic composition comprising mycoplasma antigens
WO2014105672A1 (en) 2012-12-28 2014-07-03 Boehringer Ingelheim Vetmedica Gmbh Method of making a mycoplasma vaccine
EP2913947B1 (en) * 2014-02-27 2019-11-27 ADVA Optical Networking SE Passive optical network and optical line terminal
KR20160099223A (ko) * 2015-02-12 2016-08-22 강원대학교산학협력단 마이코플라스마 하이오뉴모니애 박테린 백신 및 이의 제조방법
US10071149B2 (en) 2016-05-03 2018-09-11 Brigham Young University Temperature sensitive multivalent Bordetella avium vaccines
CN113278575B (zh) * 2021-07-13 2021-12-31 南华大学 一种肺炎支原体减毒突变株及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN178995A0 (en) * 1995-03-16 1995-04-13 University Of Melbourne, The Antigen composition
CN1100871C (zh) * 1999-06-25 2003-02-05 江苏省农业科学院畜牧兽医研究所 猪肺炎支原体克隆致弱株
US6673567B2 (en) * 2000-03-23 2004-01-06 E. I. Du Pont De Nemours And Company Method of determination of gene function
US6585981B1 (en) * 2000-07-27 2003-07-01 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for Mycoplasma hyopneumoniae
MY129765A (en) * 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
EP1521592A2 (en) * 2001-07-02 2005-04-13 Pfizer Products Inc. Mycoplasma hyopneumoniae vaccine and methods for reducing mycoplasma bovis pneumonia in cattle
US7691368B2 (en) * 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
BRPI0708522A2 (pt) * 2006-03-03 2011-05-31 Merial Ltd vacina de mycoplasma hyopneumoniae
EP2217271B1 (en) * 2007-11-06 2016-05-04 Zoetis Services LLC Mycoplasma hyopneumoniae avirulent -adjuvanted live vaccine
SI2475384T1 (sl) * 2009-09-10 2016-12-30 Merial, Inc. Nove formulacije cepiva, ki obsegajo adjuvante, vsebujoče saponin
US9324223B2 (en) 2012-06-08 2016-04-26 3M Innovative Properties Company Electronic monitoring home unit and installation methods

Also Published As

Publication number Publication date
JP5744852B2 (ja) 2015-07-08
ZA201109185B (en) 2012-09-26
KR20120016282A (ko) 2012-02-23
NZ596722A (en) 2013-08-30
PE20120909A1 (es) 2012-08-19
BRPI1010679A2 (pt) 2017-07-18
KR101734590B1 (ko) 2017-05-11
BRPI1010679B1 (pt) 2020-09-24
AU2010251761B2 (en) 2014-10-09
EP2453913A1 (en) 2012-05-23
EP2453913A4 (en) 2013-10-30
CN102458462B (zh) 2014-03-19
JP2012527218A (ja) 2012-11-08
US8524252B2 (en) 2013-09-03
CL2011002923A1 (es) 2012-08-31
EA021102B1 (ru) 2015-04-30
US20120135040A1 (en) 2012-05-31
ES2579935T3 (es) 2016-08-17
CN102458462A (zh) 2012-05-16
DK2453913T3 (en) 2016-07-25
AU2010251761A1 (en) 2011-12-22
MX2011012362A (es) 2012-04-19
CA2762587A1 (en) 2010-11-25
WO2010132932A1 (en) 2010-11-25
EP2453913B1 (en) 2016-06-22
CA2762587C (en) 2017-11-28

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