EA021093B9 - Устройство и способ акустического фокусирования частиц - Google Patents
Устройство и способ акустического фокусирования частицInfo
- Publication number
- EA021093B9 EA021093B9 EA201001165A EA201001165A EA021093B9 EA 021093 B9 EA021093 B9 EA 021093B9 EA 201001165 A EA201001165 A EA 201001165A EA 201001165 A EA201001165 A EA 201001165A EA 021093 B9 EA021093 B9 EA 021093B9
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- capillary
- focusing
- vibration source
- stream particles
- groove
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 2
- 239000012530 fluid Substances 0.000 abstract 2
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 238000003754 machining Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
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- G—PHYSICS
- G10—MUSICAL INSTRUMENTS; ACOUSTICS
- G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
- G10K15/00—Acoustics not otherwise provided for
- G10K15/02—Synthesis of acoustic waves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1413—Hydrodynamic focussing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1415—Control of particle position
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/142—Acoustic or ultrasonic focussing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0391—Affecting flow by the addition of material or energy
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/218—Means to regulate or vary operation of device
- Y10T137/2191—By non-fluid energy field affecting input [e.g., transducer]
- Y10T137/2196—Acoustical or thermal energy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/42—Piezoelectric device making
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Acoustics & Sound (AREA)
- Multimedia (AREA)
- Engineering & Computer Science (AREA)
- Audiology, Speech & Language Pathology (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
- Powder Metallurgy (AREA)
- Measuring Fluid Pressure (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
Акустически фокусирующий капилляр включает капилляр, присоединенный по крайней мере к одному источнику вибрации, имеющему канавку. Способ изготовления подобного акустического фокусирующего капилляра включает обеспечение капилляра и источника вибрации, изготовление канавки в источнике вибрации и присоединение источника вибрации к капилляру у канавки. Другой способ относится к фокусировке потока частиц и включает пропускание потока защитной жидкости в наружную границу капилляра, пропускание потока частиц в центральную сердцевину капилляра и акустическую фокусировку потока частиц путем применения акустического давления излучения к потоку частиц в первом местоположении вдоль капилляра. Поток частиц может быть далее сфокусирован путем гидродинамической фокусировки во втором местоположении вдоль нижнего потока капилляра в первом местоположении.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2144308P | 2008-01-16 | 2008-01-16 | |
US12/209,084 US8714014B2 (en) | 2008-01-16 | 2008-09-11 | System and method for acoustic focusing hardware and implementations |
PCT/US2009/031154 WO2009091925A2 (en) | 2008-01-16 | 2009-01-15 | System and method for acoustic focusing hardware and implementations |
Publications (3)
Publication Number | Publication Date |
---|---|
EA201001165A1 EA201001165A1 (ru) | 2011-02-28 |
EA021093B1 EA021093B1 (ru) | 2015-04-30 |
EA021093B9 true EA021093B9 (ru) | 2016-01-29 |
Family
ID=40849627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201001165A EA021093B9 (ru) | 2008-01-16 | 2009-01-15 | Устройство и способ акустического фокусирования частиц |
Country Status (13)
Country | Link |
---|---|
US (5) | US8714014B2 (ru) |
EP (1) | EP2240927B1 (ru) |
JP (4) | JP5364725B2 (ru) |
KR (3) | KR20160002927A (ru) |
CN (3) | CN101971247A (ru) |
AU (1) | AU2009206101B2 (ru) |
BR (1) | BRPI0906520A2 (ru) |
CA (1) | CA2710024C (ru) |
EA (1) | EA021093B9 (ru) |
IL (1) | IL206560A0 (ru) |
SG (1) | SG193165A1 (ru) |
WO (1) | WO2009091925A2 (ru) |
ZA (1) | ZA201005045B (ru) |
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RU2224992C2 (ru) * | 1998-02-20 | 2004-02-27 | Кси, Инк. | Вибрационная система для проточного цитометра, предназначенного для сортинга |
US20020129669A1 (en) * | 1999-12-03 | 2002-09-19 | Xy, Inc. | Low acceleration method of flow cytometry |
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WO2006076195A2 (en) * | 2005-01-12 | 2006-07-20 | Beckman Coulter, Inc. | Methods and apparatus for sorting particles hydraulically |
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