EA020959B1 - Пептиды, специфичные к меланокортиновым рецепторам - Google Patents

Пептиды, специфичные к меланокортиновым рецепторам Download PDF

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Publication number
EA020959B1
EA020959B1 EA201190338A EA201190338A EA020959B1 EA 020959 B1 EA020959 B1 EA 020959B1 EA 201190338 A EA201190338 A EA 201190338A EA 201190338 A EA201190338 A EA 201190338A EA 020959 B1 EA020959 B1 EA 020959B1
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EA
Eurasian Patent Office
Prior art keywords
agd
peptides
present
xaa
peptide
Prior art date
Application number
EA201190338A
Other languages
English (en)
Russian (ru)
Other versions
EA201190338A1 (ru
Inventor
Йи-Цунь Ши
Шубх Д. Шарма
Джон Г. Додд
Вей Ян
Син Чень
Original Assignee
Палатин Текнолоджиз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Палатин Текнолоджиз, Инк. filed Critical Палатин Текнолоджиз, Инк.
Publication of EA201190338A1 publication Critical patent/EA201190338A1/ru
Publication of EA020959B1 publication Critical patent/EA020959B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/16—Fluorine compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EA201190338A 2009-06-08 2010-06-07 Пептиды, специфичные к меланокортиновым рецепторам EA020959B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18492909P 2009-06-08 2009-06-08
PCT/US2010/037589 WO2010144344A2 (en) 2009-06-08 2010-06-07 Melanocortin receptor-specific peptides

Publications (2)

Publication Number Publication Date
EA201190338A1 EA201190338A1 (ru) 2012-06-29
EA020959B1 true EA020959B1 (ru) 2015-03-31

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA201190338A EA020959B1 (ru) 2009-06-08 2010-06-07 Пептиды, специфичные к меланокортиновым рецепторам

Country Status (14)

Country Link
US (4) US8846601B2 (enExample)
EP (1) EP2440227B1 (enExample)
JP (1) JP5805632B2 (enExample)
KR (1) KR101726893B1 (enExample)
CN (2) CN102458436B (enExample)
AU (1) AU2010259008C1 (enExample)
BR (1) BRPI1009644B1 (enExample)
CA (1) CA2761607C (enExample)
EA (1) EA020959B1 (enExample)
IL (1) IL216843A (enExample)
MX (1) MX2011013117A (enExample)
NZ (1) NZ596617A (enExample)
WO (1) WO2010144344A2 (enExample)
ZA (1) ZA201200112B (enExample)

Cited By (1)

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RU2785889C1 (ru) * 2015-09-30 2022-12-14 Ритм Фармасьютикалз, Инк. Способ лечения нарушений, ассоциированных с путем рецептора меланокортина 4

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CA2825098C (en) 2011-01-27 2020-03-10 Universite De Montreal Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators
HRP20211950T1 (hr) 2011-12-29 2022-03-18 Rhythm Pharmaceuticals, Inc. Postupak liječenja poremećaja u vezi sa melanokortin-4 receptorom u heterozigotnim nosiocima
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CN104436159A (zh) * 2014-12-09 2015-03-25 天津医科大学眼科医院 一种新型滴眼液对治疗干眼的用途
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MX2020009900A (es) * 2018-03-23 2021-01-08 Palatin Technologies Inc Formulaciones peptidicas especificas para el receptor de melanocortinas y metodos para un suministro especifico en el tubo gastrointestinal.
EP3773897A1 (en) 2018-04-06 2021-02-17 Rhythm Pharmaceuticals, Inc. Compositions for treating kidney disease
JP7817168B2 (ja) * 2020-02-03 2026-02-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ジアミン連結受容体特異的環状ペプチド
EP4100042A4 (en) * 2020-02-03 2024-04-10 Palatin Technologies, Inc. Reverse amide-linked melanocortin receptor-specific cyclic peptides
CN114890958B (zh) * 2022-02-23 2023-10-20 四川警察学院 双光子染料化合物、其制备方法及其应用
CN115521356B (zh) * 2022-08-17 2024-04-02 桂林医学院 一种具有美白功效的多肽及其应用
CN119529031B (zh) * 2024-11-27 2025-12-05 润辉生物技术（威海）有限公司 一种环肽衍生物及其制备方法与应用

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2785889C1 (ru) * 2015-09-30 2022-12-14 Ритм Фармасьютикалз, Инк. Способ лечения нарушений, ассоциированных с путем рецептора меланокортина 4

Also Published As

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WO2010144344A3 (en) 2011-02-03
AU2010259008B2 (en) 2014-12-04
JP5805632B2 (ja) 2015-11-04
US9458201B2 (en) 2016-10-04
US20120178701A1 (en) 2012-07-12
IL216843A0 (en) 2012-02-29
CN102458436B (zh) 2015-06-03
US8846601B2 (en) 2014-09-30
US10179804B2 (en) 2019-01-15
EP2440227A2 (en) 2012-04-18
CN102458436A (zh) 2012-05-16
AU2010259008A1 (en) 2011-11-24
EA201190338A1 (ru) 2012-06-29
EP2440227A4 (en) 2013-03-20
BRPI1009644B1 (pt) 2022-02-08
MX2011013117A (es) 2012-05-23
JP2012529433A (ja) 2012-11-22
US10632171B2 (en) 2020-04-28
US20160318977A1 (en) 2016-11-03
KR20120092089A (ko) 2012-08-20
NZ596617A (en) 2014-04-30
ZA201200112B (en) 2013-06-26
BRPI1009644A2 (pt) 2020-06-23
IL216843A (en) 2016-11-30
EP2440227B1 (en) 2017-10-18
CA2761607A1 (en) 2010-12-16
WO2010144344A2 (en) 2010-12-16
AU2010259008C1 (en) 2016-04-21
US20190216887A1 (en) 2019-07-18
US20140357575A1 (en) 2014-12-04
CN105037502A (zh) 2015-11-11
CA2761607C (en) 2018-09-04
KR101726893B1 (ko) 2017-04-13

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