CA2761607C - Melanocortin receptor-specific peptides - Google Patents

Melanocortin receptor-specific peptides Download PDF

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Publication number
CA2761607C
CA2761607C CA2761607A CA2761607A CA2761607C CA 2761607 C CA2761607 C CA 2761607C CA 2761607 A CA2761607 A CA 2761607A CA 2761607 A CA2761607 A CA 2761607A CA 2761607 C CA2761607 C CA 2761607C
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CA
Canada
Prior art keywords
arg
peptides
phe
trp
cyc
Prior art date
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Active
Application number
CA2761607A
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English (en)
French (fr)
Other versions
CA2761607A1 (en
Inventor
Yi-Qun Shi
Shubh D. Sharma
John H. Dodd
Wei Yang
Xin Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Palatin Technologies Inc
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Palatin Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palatin Technologies Inc filed Critical Palatin Technologies Inc
Publication of CA2761607A1 publication Critical patent/CA2761607A1/en
Application granted granted Critical
Publication of CA2761607C publication Critical patent/CA2761607C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/16—Fluorine compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2761607A 2009-06-08 2010-06-07 Melanocortin receptor-specific peptides Active CA2761607C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18492909P 2009-06-08 2009-06-08
US61/184,929 2009-06-08
PCT/US2010/037589 WO2010144344A2 (en) 2009-06-08 2010-06-07 Melanocortin receptor-specific peptides

Publications (2)

Publication Number Publication Date
CA2761607A1 CA2761607A1 (en) 2010-12-16
CA2761607C true CA2761607C (en) 2018-09-04

Family

ID=43309425

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2761607A Active CA2761607C (en) 2009-06-08 2010-06-07 Melanocortin receptor-specific peptides

Country Status (14)

Country Link
US (4) US8846601B2 (enExample)
EP (1) EP2440227B1 (enExample)
JP (1) JP5805632B2 (enExample)
KR (1) KR101726893B1 (enExample)
CN (2) CN102458436B (enExample)
AU (1) AU2010259008C1 (enExample)
BR (1) BRPI1009644B1 (enExample)
CA (1) CA2761607C (enExample)
EA (1) EA020959B1 (enExample)
IL (1) IL216843A (enExample)
MX (1) MX2011013117A (enExample)
NZ (1) NZ596617A (enExample)
WO (1) WO2010144344A2 (enExample)
ZA (1) ZA201200112B (enExample)

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MX2020009900A (es) * 2018-03-23 2021-01-08 Palatin Technologies Inc Formulaciones peptidicas especificas para el receptor de melanocortinas y metodos para un suministro especifico en el tubo gastrointestinal.
EP3773897A1 (en) 2018-04-06 2021-02-17 Rhythm Pharmaceuticals, Inc. Compositions for treating kidney disease
JP7817168B2 (ja) * 2020-02-03 2026-02-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ジアミン連結受容体特異的環状ペプチド
EP4100042A4 (en) * 2020-02-03 2024-04-10 Palatin Technologies, Inc. Reverse amide-linked melanocortin receptor-specific cyclic peptides
CN114890958B (zh) * 2022-02-23 2023-10-20 四川警察学院 双光子染料化合物、其制备方法及其应用
CN115521356B (zh) * 2022-08-17 2024-04-02 桂林医学院 一种具有美白功效的多肽及其应用
CN119529031B (zh) * 2024-11-27 2025-12-05 润辉生物技术（威海）有限公司 一种环肽衍生物及其制备方法与应用

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Also Published As

Publication number Publication date
WO2010144344A3 (en) 2011-02-03
AU2010259008B2 (en) 2014-12-04
JP5805632B2 (ja) 2015-11-04
US9458201B2 (en) 2016-10-04
US20120178701A1 (en) 2012-07-12
IL216843A0 (en) 2012-02-29
CN102458436B (zh) 2015-06-03
US8846601B2 (en) 2014-09-30
US10179804B2 (en) 2019-01-15
EP2440227A2 (en) 2012-04-18
CN102458436A (zh) 2012-05-16
AU2010259008A1 (en) 2011-11-24
EA020959B1 (ru) 2015-03-31
EA201190338A1 (ru) 2012-06-29
EP2440227A4 (en) 2013-03-20
BRPI1009644B1 (pt) 2022-02-08
MX2011013117A (es) 2012-05-23
JP2012529433A (ja) 2012-11-22
US10632171B2 (en) 2020-04-28
US20160318977A1 (en) 2016-11-03
KR20120092089A (ko) 2012-08-20
NZ596617A (en) 2014-04-30
ZA201200112B (en) 2013-06-26
BRPI1009644A2 (pt) 2020-06-23
IL216843A (en) 2016-11-30
EP2440227B1 (en) 2017-10-18
CA2761607A1 (en) 2010-12-16
WO2010144344A2 (en) 2010-12-16
AU2010259008C1 (en) 2016-04-21
US20190216887A1 (en) 2019-07-18
US20140357575A1 (en) 2014-12-04
CN105037502A (zh) 2015-11-11
KR101726893B1 (ko) 2017-04-13

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