EA012176B1 - Новое применение пептидных соединений для лечения боли при болезненной диабетической нейропатии - Google Patents
Новое применение пептидных соединений для лечения боли при болезненной диабетической нейропатии Download PDFInfo
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- EA012176B1 EA012176B1 EA200601777A EA200601777A EA012176B1 EA 012176 B1 EA012176 B1 EA 012176B1 EA 200601777 A EA200601777 A EA 200601777A EA 200601777 A EA200601777 A EA 200601777A EA 012176 B1 EA012176 B1 EA 012176B1
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- Prior art keywords
- pain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55649904P | 2004-03-26 | 2004-03-26 | |
| EP04007360A EP1579858A1 (en) | 2004-03-26 | 2004-03-26 | Novel use of peptide compounds for treating pain in painful diabetic neuropathy |
| PCT/EP2005/003176 WO2005092313A1 (en) | 2004-03-26 | 2005-03-24 | Novel use of peptide compounds for treating pain in painful diabetic neuropathy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200601777A1 EA200601777A1 (ru) | 2007-02-27 |
| EA012176B1 true EA012176B1 (ru) | 2009-08-28 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200601777A EA012176B1 (ru) | 2004-03-26 | 2005-03-24 | Новое применение пептидных соединений для лечения боли при болезненной диабетической нейропатии |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060100157A1 (https=) |
| EP (2) | EP1579858A1 (https=) |
| JP (1) | JP2007530493A (https=) |
| CN (1) | CN1938010B (https=) |
| AU (1) | AU2005226928B2 (https=) |
| BR (1) | BRPI0509211A (https=) |
| CA (1) | CA2558311A1 (https=) |
| EA (1) | EA012176B1 (https=) |
| MX (1) | MXPA06010995A (https=) |
| NZ (1) | NZ549668A (https=) |
| SG (1) | SG151309A1 (https=) |
| TW (1) | TW200701977A (https=) |
| UA (1) | UA90467C2 (https=) |
| WO (1) | WO2005092313A1 (https=) |
| ZA (1) | ZA200607269B (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1243262T3 (da) | 2001-03-20 | 2006-10-02 | Sanol Arznei Schwarz Gmbh | Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter |
| ES2185606T3 (es) | 2001-03-21 | 2003-05-01 | Sanol Arznei Schwarz Gmbh | Nuevo uso de una clase de compuestos peptidicos para tratamiento de la alodinia u otros tipos diferentes de dolor cronico o fantasma. |
| JP4664924B2 (ja) | 2003-12-02 | 2011-04-06 | ウーツェーベー ファルマ ゲーエムベーハー | 中枢神経因性疼痛の治療のためのペプチド化合物の新規使用 |
| US20070042969A1 (en) * | 2004-03-26 | 2007-02-22 | Srz Properties, Inc. | Combination therapy for pain in painful diabetic neuropathy |
| US20100256179A1 (en) * | 2004-03-26 | 2010-10-07 | Ucb Pharma Gmbh | Combination therapy for pain in painful diabetic neuropathy |
| KR20070007931A (ko) | 2004-04-16 | 2007-01-16 | 쉬바르츠파르마에이지 | 만성 두통의 예방 및 치료를 위한 펩티드 화합물의 용도 |
| EP1604655A1 (en) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in trigeminal neuralgia |
| PL1781276T3 (pl) | 2004-08-27 | 2010-11-30 | Ucb Pharma Gmbh | Zastosowanie związków peptydowych do leczenia bólu związanego z rakiem kości, bólu indukowanego przez chemioterapię oraz nukleozydy |
| EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
| US20060252749A1 (en) * | 2005-01-28 | 2006-11-09 | Srz Properties, Inc. | Lacosamide for add-on therapy of psychosis |
| EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
| US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
| US7902401B2 (en) * | 2006-12-14 | 2011-03-08 | Nps Pharmaceuticals, Inc. | Fluorinated compounds |
| GB0603008D0 (en) * | 2006-02-14 | 2006-03-29 | Portela & Ca Sa | Method |
| JP2009539792A (ja) * | 2006-06-08 | 2009-11-19 | シュヴァルツ・ファーマ・アーゲー | 疼痛の医学的状態のための治療組合せ |
| EP1873527A1 (en) * | 2006-06-30 | 2008-01-02 | Schwarz Pharma Ag | Method for identifying CRMP modulators |
| CN101466390B (zh) | 2006-06-15 | 2014-03-12 | 优时比制药有限公司 | 用于治疗难治性癫痫持续状态的肽类化合物 |
| WO2007144195A2 (en) | 2006-06-15 | 2007-12-21 | Schwarz Pharma Ag | Pharmaceutical composition with synergistic anticonvulsant effect |
| CA2672494A1 (en) * | 2006-12-14 | 2008-06-19 | Nps Pharmaceuticals, Inc. | Use of d-serine derivatives for the treatment of anxiety disorders |
| CA2774569A1 (en) * | 2009-09-23 | 2011-03-31 | The University Of North Carolina At Chapel Hill | Novel n-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents |
| MX350056B (es) | 2009-11-03 | 2017-08-25 | Lupin Ltd | Formulacion de liberacion modificada de lacosamida. |
| EP2468261A1 (en) | 2010-12-02 | 2012-06-27 | UCB Pharma GmbH | Formulation of lacosamide |
| MX2013005974A (es) | 2010-12-02 | 2013-07-29 | Ucb Pharma Gmbh | Formulacion de lacosamida de administracion una vez al dia. |
| CN109069480A (zh) | 2015-12-30 | 2018-12-21 | 阿达玛斯医药公司 | 用于治疗与癫痫相关的病症的方法和组合物 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000051586A2 (en) * | 1999-03-01 | 2000-09-08 | Nps Pharmaceuticals, Inc. | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting modulation of cns activity with isovaleramide, isovaleric acid, or a related compound |
| WO2002013766A2 (en) * | 2000-08-17 | 2002-02-21 | Teva Pharmaceutical Industries, Ltd. | Valproic acid derivatives for the treatment of pain |
| WO2002015922A2 (en) * | 2000-08-25 | 2002-02-28 | Research Corporation Technologies, Inc. | New uses for amino acid anticonvulsants for treatment of pain |
| WO2002074297A1 (en) * | 2001-03-21 | 2002-09-26 | Schwarz Pharma Ag | Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5378729A (en) * | 1985-02-15 | 1995-01-03 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
| US5585358A (en) * | 1993-07-06 | 1996-12-17 | Yissum Research Development Corporation Of The Hebrew University Of Jerusalem | Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents |
| DK1243262T3 (da) * | 2001-03-20 | 2006-10-02 | Sanol Arznei Schwarz Gmbh | Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter |
| JP4664924B2 (ja) * | 2003-12-02 | 2011-04-06 | ウーツェーベー ファルマ ゲーエムベーハー | 中枢神経因性疼痛の治療のためのペプチド化合物の新規使用 |
| US20060009384A1 (en) * | 2003-12-05 | 2006-01-12 | David Rudd | Novel use of peptide compounds for treating status epilepticus or related conditions |
| US20070042969A1 (en) * | 2004-03-26 | 2007-02-22 | Srz Properties, Inc. | Combination therapy for pain in painful diabetic neuropathy |
| KR20070007931A (ko) * | 2004-04-16 | 2007-01-16 | 쉬바르츠파르마에이지 | 만성 두통의 예방 및 치료를 위한 펩티드 화합물의 용도 |
| EP1604654A1 (en) * | 2004-05-18 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating dyskinesia |
| EP1604656A1 (en) * | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS) |
| US7427601B2 (en) * | 2004-06-24 | 2008-09-23 | Schwarz Pharma Ag | Method for treating tremor |
| EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
| US20060252749A1 (en) * | 2005-01-28 | 2006-11-09 | Srz Properties, Inc. | Lacosamide for add-on therapy of psychosis |
| US20070048372A1 (en) * | 2005-08-18 | 2007-03-01 | Srz Properties, Inc. | Method for treating non-inflammatory osteoarthritic pain |
| EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
| US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
-
2004
- 2004-03-26 EP EP04007360A patent/EP1579858A1/en not_active Withdrawn
-
2005
- 2005-03-24 JP JP2007504367A patent/JP2007530493A/ja active Pending
- 2005-03-24 NZ NZ549668A patent/NZ549668A/en unknown
- 2005-03-24 CA CA002558311A patent/CA2558311A1/en not_active Abandoned
- 2005-03-24 AU AU2005226928A patent/AU2005226928B2/en not_active Ceased
- 2005-03-24 WO PCT/EP2005/003176 patent/WO2005092313A1/en not_active Ceased
- 2005-03-24 MX MXPA06010995A patent/MXPA06010995A/es active IP Right Grant
- 2005-03-24 SG SG200902059-5A patent/SG151309A1/en unknown
- 2005-03-24 UA UAA200610139A patent/UA90467C2/ru unknown
- 2005-03-24 EA EA200601777A patent/EA012176B1/ru not_active IP Right Cessation
- 2005-03-24 CN CN2005800097824A patent/CN1938010B/zh not_active Expired - Fee Related
- 2005-03-24 BR BRPI0509211-6A patent/BRPI0509211A/pt not_active IP Right Cessation
- 2005-03-24 EP EP05716372A patent/EP1737437A1/en not_active Withdrawn
- 2005-03-25 US US11/089,441 patent/US20060100157A1/en not_active Abandoned
- 2005-07-11 TW TW094123447A patent/TW200701977A/zh unknown
-
2006
- 2006-08-31 ZA ZA200607269A patent/ZA200607269B/xx unknown
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| WO2000051586A2 (en) * | 1999-03-01 | 2000-09-08 | Nps Pharmaceuticals, Inc. | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting modulation of cns activity with isovaleramide, isovaleric acid, or a related compound |
| WO2002013766A2 (en) * | 2000-08-17 | 2002-02-21 | Teva Pharmaceutical Industries, Ltd. | Valproic acid derivatives for the treatment of pain |
| WO2002015922A2 (en) * | 2000-08-25 | 2002-02-28 | Research Corporation Technologies, Inc. | New uses for amino acid anticonvulsants for treatment of pain |
| WO2002074297A1 (en) * | 2001-03-21 | 2002-09-26 | Schwarz Pharma Ag | Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain |
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| HOVINGA C.A.: "SPM-927" IDRUGS, CURRENT DRUGS LTD., GB, vol. 6, no. 5, May 2003 (2003-05), pages 479-485, XP001180322, ISSN: 1369-7056, page 479, columns 1-2, page 480, column 1, last paragraph - page 480, column 2, paragraph 1, page 481, column 2, paragraph 3, page 482, column 2, paragraphs 2, 3 * |
| MCLEANE G. ET AL.: "DOES SPM 927 HAVE AN ANALGESIC EFFECT IN HUMAN NEUROPATHIC PAIN? AN OPEN LABEL STUDY", NEUROSCIENCE LETTERS, LIMERICK, IE, vol. 352, no. 2, 4 December 2003 (2003-12-04), pages 117-120, XP001180320, ISSN: 0304-3940, abstract, page 120, column 1; table 1 * |
| WILSON RODGER: "NON-INSULIN-DEPENDENT (TYPE II) DIABETES MELLITUS", CMAJ. CANADIAN MEDICAL ASSOCIATION JOURNAL, THE ASSOCIATION, OTTAWA, CA, vol. 145, no. 12, 15 December 1991 (1991-12-15), pages 1571-1581, XP000431270, ISSN: 0820-3946, the whole document * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005092313A1 (en) | 2005-10-06 |
| EP1737437A1 (en) | 2007-01-03 |
| BRPI0509211A (pt) | 2007-08-28 |
| SG151309A1 (en) | 2009-04-30 |
| AU2005226928A1 (en) | 2005-10-06 |
| ZA200607269B (en) | 2008-04-30 |
| EP1579858A1 (en) | 2005-09-28 |
| CN1938010B (zh) | 2011-01-19 |
| CA2558311A1 (en) | 2005-10-06 |
| UA90467C2 (ru) | 2010-05-11 |
| TW200701977A (en) | 2007-01-16 |
| CN1938010A (zh) | 2007-03-28 |
| MXPA06010995A (es) | 2007-04-16 |
| EA200601777A1 (ru) | 2007-02-27 |
| NZ549668A (en) | 2010-07-30 |
| JP2007530493A (ja) | 2007-11-01 |
| US20060100157A1 (en) | 2006-05-11 |
| AU2005226928B2 (en) | 2010-05-13 |
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