EA007075B1 - Фармацевтические композиции, содержащие бета-лапахон или его производные или аналоги, и способы их применения - Google Patents

Фармацевтические композиции, содержащие бета-лапахон или его производные или аналоги, и способы их применения Download PDF

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Publication number
EA007075B1
EA007075B1 EA200400242A EA200400242A EA007075B1 EA 007075 B1 EA007075 B1 EA 007075B1 EA 200400242 A EA200400242 A EA 200400242A EA 200400242 A EA200400242 A EA 200400242A EA 007075 B1 EA007075 B1 EA 007075B1
Authority
EA
Eurasian Patent Office
Prior art keywords
lapachone
pharmaceutically acceptable
pharmaceutical composition
cyclodextrin
derivative
Prior art date
Application number
EA200400242A
Other languages
English (en)
Russian (ru)
Other versions
EA200400242A1 (ru
Inventor
Зивей Дзианг
Дашаратха Дж. Редди
Original Assignee
Аркьюл, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аркьюл, Инк. filed Critical Аркьюл, Инк.
Publication of EA200400242A1 publication Critical patent/EA200400242A1/ru
Publication of EA007075B1 publication Critical patent/EA007075B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
EA200400242A 2001-07-31 2002-07-31 Фармацевтические композиции, содержащие бета-лапахон или его производные или аналоги, и способы их применения EA007075B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30893501P 2001-07-31 2001-07-31
US09/975,776 US6962944B2 (en) 2001-07-31 2001-10-10 Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same
PCT/US2002/024262 WO2003011224A2 (en) 2001-07-31 2002-07-31 Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same

Publications (2)

Publication Number Publication Date
EA200400242A1 EA200400242A1 (ru) 2004-12-30
EA007075B1 true EA007075B1 (ru) 2006-06-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400242A EA007075B1 (ru) 2001-07-31 2002-07-31 Фармацевтические композиции, содержащие бета-лапахон или его производные или аналоги, и способы их применения

Country Status (13)

Country Link
US (1) US6962944B2 (cg-RX-API-DMAC10.html)
EP (1) EP1420777A4 (cg-RX-API-DMAC10.html)
JP (1) JP2005507861A (cg-RX-API-DMAC10.html)
KR (1) KR100734341B1 (cg-RX-API-DMAC10.html)
CN (1) CN1561209A (cg-RX-API-DMAC10.html)
AU (1) AU2002313713B2 (cg-RX-API-DMAC10.html)
BR (1) BR0211613A (cg-RX-API-DMAC10.html)
CA (1) CA2455567A1 (cg-RX-API-DMAC10.html)
EA (1) EA007075B1 (cg-RX-API-DMAC10.html)
IL (2) IL160108A0 (cg-RX-API-DMAC10.html)
MX (1) MXPA04000994A (cg-RX-API-DMAC10.html)
NZ (1) NZ531335A (cg-RX-API-DMAC10.html)
WO (1) WO2003011224A2 (cg-RX-API-DMAC10.html)

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CA2555950A1 (en) 2004-02-20 2005-09-09 Arqule, Inc. Use of beta-lapachone for the treatment of pancreatic cancer
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RU2530886C1 (ru) * 2013-06-24 2014-10-20 Государственное бюджетное учреждение "Уфимский научно-исследовательский институт глазных болезней Академии наук Республики Башкортостан" Водорастворимый комплекс включения бета-циклодекстрин-гистохром, обладающий пролонгированным антиоксидантным действием
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CN112076157B (zh) * 2019-06-14 2022-04-26 首都医科大学 拉帕醇纳米脂质体制剂及其制备方法和应用
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Also Published As

Publication number Publication date
US20030091639A1 (en) 2003-05-15
US6962944B2 (en) 2005-11-08
CN1561209A (zh) 2005-01-05
NZ531335A (en) 2007-08-31
JP2005507861A (ja) 2005-03-24
CA2455567A1 (en) 2003-02-13
EP1420777A2 (en) 2004-05-26
IL192937A0 (en) 2009-02-11
BR0211613A (pt) 2004-11-09
KR100734341B1 (ko) 2007-07-03
AU2002313713B2 (en) 2007-03-29
WO2003011224A2 (en) 2003-02-13
EA200400242A1 (ru) 2004-12-30
MXPA04000994A (es) 2005-02-17
IL160108A0 (en) 2004-06-20
WO2003011224A3 (en) 2003-05-08
KR20040054667A (ko) 2004-06-25
EP1420777A4 (en) 2009-03-04

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