DZ3384A1 - Procede d'obtention de formulations aqueuses de principes actifs sensibles a l'oxydation - Google Patents

Procede d'obtention de formulations aqueuses de principes actifs sensibles a l'oxydation

Info

Publication number
DZ3384A1
DZ3384A1 DZ013384A DZ013384A DZ3384A1 DZ 3384 A1 DZ3384 A1 DZ 3384A1 DZ 013384 A DZ013384 A DZ 013384A DZ 013384 A DZ013384 A DZ 013384A DZ 3384 A1 DZ3384 A1 DZ 3384A1
Authority
DZ
Algeria
Prior art keywords
oxidation
active ingredients
aqueous formulations
sensitive active
obtaining aqueous
Prior art date
Application number
DZ013384A
Other languages
English (en)
French (fr)
Inventor
Francois Dietlin
Daniele Fredj
Original Assignee
Pharmatop Scr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8851012&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DZ3384(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmatop Scr filed Critical Pharmatop Scr
Application granted granted Critical
Publication of DZ3384A1 publication Critical patent/DZ3384A1/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D19/00—Degasification of liquids
    • B01D19/0005—Degasification of liquids with one or more auxiliary substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Removal Of Specific Substances (AREA)
DZ013384A 2000-06-06 2001-06-06 Procede d'obtention de formulations aqueuses de principes actifs sensibles a l'oxydation DZ3384A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0007231A FR2809619B1 (fr) 2000-06-06 2000-06-06 Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
PCT/FR2001/001749 WO2001093830A1 (fr) 2000-06-06 2001-06-06 Procede d'obtention de formulations aqueuses de principes actifs sensibles a l'oxydation

Publications (1)

Publication Number Publication Date
DZ3384A1 true DZ3384A1 (fr) 2001-12-13

Family

ID=8851012

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ013384A DZ3384A1 (fr) 2000-06-06 2001-06-06 Procede d'obtention de formulations aqueuses de principes actifs sensibles a l'oxydation

Country Status (16)

Country Link
US (1) US6992218B2 (xx)
CN (1) CN1556694A (xx)
AP (1) AP1880A (xx)
AU (1) AU2001266120A1 (xx)
CA (1) CA2415403C (xx)
CZ (1) CZ200313A3 (xx)
DZ (1) DZ3384A1 (xx)
FR (1) FR2809619B1 (xx)
MA (1) MA26926A1 (xx)
MX (1) MXPA03000001A (xx)
NZ (1) NZ523458A (xx)
PE (1) PE20030508A1 (xx)
RU (1) RU2003100090A (xx)
TW (1) TWI237570B (xx)
WO (1) WO2001093830A1 (xx)
YU (1) YU103A (xx)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2809619B1 (fr) * 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
ITMI20012135A1 (it) 2001-10-16 2003-04-16 Bioren S A Soluzioni iniettabili pronte all'uso di paracetamolo
FR2832063B1 (fr) * 2001-11-15 2004-08-27 Aguettant Lab Procede de production de solutions stables de substances phenoliques et les solutions en resultant
FR2851164B1 (fr) * 2003-02-14 2005-04-22 Xuan Tho Nguyen Formulation liquide injectable de paracetamol
US20050020554A1 (en) * 2003-06-06 2005-01-27 Ahmed Salah U. Stability of hormone formulations
FR2880807B1 (fr) * 2005-01-19 2007-04-13 Aguettant Sa Lab Composition pharmaceutique injectable
ES2564194T3 (es) 2005-02-09 2016-03-18 Santen Pharmaceutical Co., Ltd. Formulaciones líquidas para el tratamiento de enfermedades o dolencias
DE102005037653A1 (de) * 2005-08-05 2007-02-15 Theraselect Gmbh Stabile, flüssige Formulierung von Paracetamol
US20070077303A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for providing oxidatively stable ophthalmic compositions
FR2894154B1 (fr) * 2005-12-06 2008-03-14 Pharmatop Scr Nouveau procede de stabilisation de substances minerales ou organiques sensibles a l'oxydation.
BRPI0707612B8 (pt) 2006-02-09 2021-05-25 Macusight Inc vaso lacrado e formulações líquidas contidas no mesmo
US8222271B2 (en) 2006-03-23 2012-07-17 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions
US20070249727A1 (en) 2006-04-21 2007-10-25 The Proctor & Gamble Company Compositions and kits useful for treatment of respiratory illness
US10022339B2 (en) 2006-04-21 2018-07-17 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
CA2628806C (en) 2006-07-18 2012-08-21 Genfarma Laboratorio S.L. Injectable liquid paracetamol formulation
EP1992334A1 (en) * 2007-05-08 2008-11-19 Docpharma NV/SA Storage-stable formulation of oxidation-sensitive phenolic drug, especially paracetamol, comprises aqueous drug solution deoxygenated by a temperature-controlled manufacturing process of the formulation
DE102007026975A1 (de) * 2007-06-01 2008-12-04 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Antioxidationsmittel für Lebensmittel
WO2009047634A2 (en) * 2007-06-18 2009-04-16 Combino Pharm, S.L. Aqueous formulations of acetaminophen for injection
AR067047A1 (es) * 2007-06-18 2009-09-30 Combino Pharm Sl Formulaciones acuosas de acetaminofen para inyeccion.
US9399012B2 (en) * 2007-11-13 2016-07-26 Mallinckrodt Ip Reduced dose intravenous acetaminophen
US20110015273A1 (en) * 2008-01-17 2011-01-20 Rajnarayana Kandhagatla Stable pharmaceutical aqueous compositions
FR2926992B1 (fr) * 2008-02-06 2011-01-14 Moly Pharma Formulation d'une solution de paracetamol injectable,procede de preparation et de conditionnement d'une telle solution et dispositif de conditionnement d'une telle solution
EA020308B1 (ru) * 2008-06-11 2014-10-30 Зюдцуккер Акциенгезельшафт Маннхайм/Оксенфурт Высокоэффективный антиокислитель на основе трегалулозы
EP2243477A1 (de) 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
US8404748B2 (en) 2009-08-13 2013-03-26 Neogen N.V. Storage-stable formulation of paracetamol in aqueous solution
EP2464332B1 (en) 2009-08-13 2016-03-02 Neogen N.V. Storage-stable formulation of paracetamol in aqueous solution
EP2481464A4 (en) 2009-09-24 2014-03-12 Toshiba Kk SOLUTION ABSORBING GASEOUS CARBON DIOXIDE
CN102711726A (zh) 2009-12-10 2012-10-03 特克尼梅德医疗技术股份公司 用于制备扑热息痛稳定液体制剂的方法和组合物
US20110207824A1 (en) * 2010-02-25 2011-08-25 Moly Pharma Formulation of an injectable paracetamol solution, method for preparing and packaging such a solution and device for packaging such a solution
US9089477B2 (en) 2011-02-10 2015-07-28 Neogen N.V. Storage-stable formulation of paracetamol in aqueous solution
PT3287123T (pt) 2011-03-04 2020-05-22 Gruenenthal Gmbh Formulação farmacêutica aquosa de tapentadol para administração oral
ES2414557B1 (es) * 2012-01-16 2014-06-10 Novocat Farma, S.A. Composición acuosa de paracetamol para inyección
ITMI20121154A1 (it) 2012-06-29 2013-12-30 Sint Sa Soluzione iniettabile di acetaminofene per la somministrazione spinale
CN103006550A (zh) * 2012-12-11 2013-04-03 哈药集团三精制药股份有限公司 一种胞磷胆碱钠注射液及其制备方法
US20140303254A1 (en) * 2013-04-08 2014-10-09 InnoPharma Licensing LLC Process Of Manufacturing A Stable, Ready To Use Infusion Bag For An Oxidation Sensitive Formulation
UY35988A (es) * 2014-02-27 2015-09-30 Sint Sa Proceso para la producción de una solución inyectable de noradrenalina de baja concentración
BR102014005885B1 (pt) 2014-03-13 2021-04-13 Biotec Biológica Indústria Farmacêutica Ltda E.P.P Formulação farmacêutica líquida injetável estável de paracetamol em bolsa plástica pronta para uso
WO2016008546A1 (en) * 2014-07-18 2016-01-21 Everbright Pharmaceuticals S.A.R.L. Aqueous formulation comprising paracetamol and ibuprofen
CN104288099B (zh) * 2014-09-25 2017-02-15 西安仁仁药业有限公司 一种布洛芬注射液的制备方法
PL3273953T3 (pl) * 2015-03-27 2019-07-31 Grünenthal GmbH Stabilny preparat do pozajelitowego podawania tapentadolu
CU24523B1 (es) 2015-06-18 2021-06-08 Estetra Sprl Unidad de dosificación orodispersable que contiene un componente estetrol
CN116077455A (zh) 2015-06-18 2023-05-09 埃斯特拉有限责任公司 含雌四醇组分的口腔分散剂量单位
EP3120837A1 (de) 2015-07-22 2017-01-25 Stada Arzneimittel Ag Verfahren zur herstellung einer bortezomibester-lösung
MX2018009497A (es) 2016-02-05 2019-05-06 Innopharma Inc Proceso para fabricar una bolsa de infusion estable, lista para su uso para una formulacion sensible a la oxidacion.
MX2019003257A (es) 2016-09-23 2019-06-10 Gruenenthal Gmbh Formulacion estable para la administracion parenteral de tapentadol.
CA3051467C (en) 2017-01-30 2022-11-29 Nevakar, Inc Norepinephrine compositions and methods therefor
WO2018192664A1 (en) * 2017-04-20 2018-10-25 Hyloris Developments Sa METHOD FOR PREPARING A COMPOSITION WITH A LOW DISSOLVED OXYGEN CONTENT, COMPRISING ACETAMINOPHEN, AND OPTIONALLY ONE OR MORE NSAIDs, AND A COMPOSITION OBTAINED THEREOF
WO2019150381A1 (en) * 2018-02-01 2019-08-08 Joshi Mahendra R A stable pharmaceutical composition and process for production of isoproterenol hydrochloride injection
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
MX2020012233A (es) 2018-05-16 2021-01-29 Bayer Healthcare Llc Formula de suspension de alta concentracion para medicamentos en capsula de gel blanda para resfriado y gripe.
EP3863589A1 (en) * 2018-10-08 2021-08-18 Merz Pharma GmbH & Co. KGaA Neurotoxin prefilled vial
US10478453B1 (en) 2019-01-15 2019-11-19 Exela Pharma Sciences, LLC Stable, highly pure L-cysteine compositions for injection and methods of use
CN113105040A (zh) * 2021-04-02 2021-07-13 武汉工控工业技术研究院有限公司 一种自然水体无菌处理及长期保存技术
CN116803376B (zh) * 2023-08-04 2024-02-13 广州白云山星群(药业)股份有限公司 一种复方愈创木酚磺酸钾口服溶液的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3443004A (en) * 1965-04-08 1969-05-06 Ciba Geigy Corp Injectable solution containing 6-chloroor 6-trifluoromethyl-7-sulfamyl - 1,2,4-benzothiodiazine-1,1-dioxide diuretic
DD153578A1 (de) * 1980-10-22 1982-01-20 Hans Meffert Stabilisierung von oxydationsempfindlichen wirkstoffen,vorrangig dithranol in arzneizubereitungen
RO93391B (ro) * 1984-12-20 1988-03-31 Eli Lilly And Company Procedeu pentru prepararea unor saruri de dobutamina
CA2126093A1 (en) * 1992-10-21 1994-04-28 Owen Gan Composition for irrigating intraocular tissues and maintaining mydriasis during intraocular surgery
AU5680994A (en) * 1992-12-10 1994-07-04 Abbott Laboratories Stabilized catecholamine solutions
FR2740338B1 (fr) * 1995-12-01 1997-12-05 Rhone Poulenc Rorer Sa Compositions pharmaceutiques stabilisees contenant de la dobutamine
FR2751875B1 (fr) * 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
FR2809619B1 (fr) * 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention

Also Published As

Publication number Publication date
CA2415403A1 (fr) 2001-12-13
US20040054012A1 (en) 2004-03-18
CN1556694A (zh) 2004-12-22
CZ200313A3 (cs) 2003-11-12
YU103A (sh) 2006-05-25
CA2415403C (fr) 2011-05-24
MA26926A1 (fr) 2004-12-20
FR2809619B1 (fr) 2004-09-24
TWI237570B (en) 2005-08-11
RU2003100090A (ru) 2004-05-10
AU2001266120A1 (en) 2001-12-17
AP2002002711A0 (en) 2002-12-31
AP1880A (en) 2008-08-19
US6992218B2 (en) 2006-01-31
WO2001093830A1 (fr) 2001-12-13
PE20030508A1 (es) 2003-06-25
MXPA03000001A (es) 2004-03-19
FR2809619A1 (fr) 2001-12-07
NZ523458A (en) 2005-08-26

Similar Documents

Publication Publication Date Title
DZ3384A1 (fr) Procede d'obtention de formulations aqueuses de principes actifs sensibles a l'oxydation
HUP0301763A3 (en) Process to prepare aqueous formulations of pesticides
ES2189989T3 (es) Desinfectante de lavado para desinfeccion higienica y quirurgica de las manos.
FR2814380B1 (fr) Poudre de microcapsules et procede d'obtention
ITMI991803A0 (it) Processo per la preparazione di formulazioni acquose per uso oftalmico
HUP0302482A3 (en) Novel surfactants and aqueous pesticide formulations
MA26881A1 (fr) 5-alkyl-pyrido [2,3-d]pyrimidines inhibitrices de tyrosine-kinases.
HK1156234A1 (en) Formulation containing phosphate derivatives of electron transfer agents
HUP0000979A1 (hu) FK-506 jelű vegyületet és származékait tartalmazó gyógyászati készítmények
ATE325179T1 (de) Trockene wirkstoffe enthaltender wasserlöslicher behälter
CA2424879A1 (en) Cleaning compositions containing chitosan
FR2818979B1 (fr) Procede de preparation d'imidaclopride
HUP0302310A3 (en) Novel formulations of alpha-2,4-disulfophenyl-n-tert-butylnitrone and process for their preparation
AU2001256324A1 (en) Process for the preparation of alkaline earth salts of d-pantothenic acid
FR2804956B1 (fr) Procede de preparation d'un compose polyaromatique
FR2779346B1 (fr) Procede d'obtention d'un principe actif anti-radicalaire et photoprotecteur, principe actif obtenu, composition cosmetique
FR2806300B1 (fr) Composition cosmetique sous forme d'un gel aqueux solide, comprenant un alcool polyvinylique et procede de preparation de cette composition
IL141607A0 (en) Microbial process for preparation of optically active 3-hydroxypyrolidine derivatives
PL357466A1 (en) Optically active 2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them
IL140127A0 (en) Process for the preparation of optically active 1,4-benzodixoane-2-carboxylic acid and derivatives thereof
AU2001259370A1 (en) Methods of obtaining active antisense compounds
FR2817761B1 (fr) Formulation decontaminante pour la decontamination d'agents toxiques epaissis
FR2808274B1 (fr) Procede de preparation des n, n'-carbonylbislactames
AU2001262746A1 (en) Process for the preparation of optically active thiazolidinone derivatives
FR2811664B1 (fr) Procede de preparation d'un compose polyaromatique