DK88586D0 - Fremgangsmaade til fremstilling af l-carnitin ad mikrobiologisk vej - Google Patents

Fremgangsmaade til fremstilling af l-carnitin ad mikrobiologisk vej

Info

Publication number
DK88586D0
DK88586D0 DK88586A DK88586A DK88586D0 DK 88586 D0 DK88586 D0 DK 88586D0 DK 88586 A DK88586 A DK 88586A DK 88586 A DK88586 A DK 88586A DK 88586 D0 DK88586 D0 DK 88586D0
Authority
DK
Denmark
Prior art keywords
carnitine
bioreactor
cell
microbiological
road
Prior art date
Application number
DK88586A
Other languages
English (en)
Other versions
DK88586A (da
DK166507B1 (da
Inventor
Hans Kulla
Pavel Lehky
Armand Squaratti
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of DK88586D0 publication Critical patent/DK88586D0/da
Publication of DK88586A publication Critical patent/DK88586A/da
Application granted granted Critical
Publication of DK166507B1 publication Critical patent/DK166507B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/007—Carnitine; Butyrobetaine; Crotonobetaine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/824—Achromobacter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/825—Actinomadura

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK088586A 1985-02-27 1986-02-26 Fremgangsmaade til kontinuerlig fremstilling af l-carnitin ad mikrobiologisk vej samt mikroorganisme til anvendelse derved DK166507B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH89085 1985-02-27
CH890/85A CH664374A5 (de) 1985-02-27 1985-02-27 Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.

Publications (3)

Publication Number Publication Date
DK88586D0 true DK88586D0 (da) 1986-02-26
DK88586A DK88586A (da) 1986-08-28
DK166507B1 DK166507B1 (da) 1993-06-01

Family

ID=4197565

Family Applications (1)

Application Number Title Priority Date Filing Date
DK088586A DK166507B1 (da) 1985-02-27 1986-02-26 Fremgangsmaade til kontinuerlig fremstilling af l-carnitin ad mikrobiologisk vej samt mikroorganisme til anvendelse derved

Country Status (9)

Country Link
US (1) US4708936A (da)
EP (1) EP0195944B1 (da)
JP (1) JP2545788B2 (da)
AT (1) ATE68211T1 (da)
CA (1) CA1247549A (da)
CH (1) CH664374A5 (da)
DE (1) DE3681811D1 (da)
DK (1) DK166507B1 (da)
IE (1) IE58779B1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD221905B1 (de) * 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
FI86889C (fi) * 1984-03-29 1992-10-26 Lonza Ag Foerfarande foer framstaellning av av l-karnitin pao mikrobiologiskt saett
FR2623520B1 (fr) * 1987-11-23 1990-04-20 Sanofi Sa Procede enzymatique continu de preparation de la l-carnitine
JPH0291049A (ja) * 1988-09-21 1990-03-30 Lonza Ag ｒ―ブチロベタインの製造方法
MX170707B (es) * 1989-07-28 1993-09-08 Lonza Ag Procedimiento para la produccion discontinua de l-carnitina por transformacion microbiologica de crotonobetaina y gama-butirobetaina
IN170700B (da) * 1989-12-20 1992-05-02 Lonza Ag
IT1261230B (it) * 1993-04-08 1996-05-09 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione.
US5750028A (en) * 1996-09-18 1998-05-12 Envirogen, Inc. Biomass separation apparatus and method with media return
US5788842A (en) * 1996-09-18 1998-08-04 Envirogen, Inc. Biomass separation apparatus and method
DE19749480A1 (de) * 1997-11-08 1999-05-20 Univ Leipzig Verfahren zur Herstellung von L-Carnitin aus Crotonobetain
US6338964B1 (en) * 1999-05-07 2002-01-15 Bayer Corporation Process and medium for mammalian cell culture under low dissolved carbon dioxide concentration
DE69932860T2 (de) * 1999-10-11 2007-08-30 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Verwendung von l-carnitin und seinen alkanoyl-derivaten als osmotisches mittel in lösungen für medizinische verwendung
US7407778B2 (en) * 2002-02-07 2008-08-05 Pettegrew Jay W Compounds, compositions and methods for treating neuropsychiatric disorders
US7700074B2 (en) * 2002-02-07 2010-04-20 Pettegrew Jay W Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism
ATE437884T1 (de) * 2003-05-29 2009-08-15 Jay W Pettegrew Glycerophosphocholin und derivate davon zur medizinischen abbildung von neuropsychiatrischen erkrankungen
US20060257842A1 (en) * 2003-05-29 2006-11-16 Pettegrew Jay W Cryopreservation media and molecules
US7611890B2 (en) * 2004-06-25 2009-11-03 Samuel Frisch System and method for separating biomass from media in a fluidized bed reactor
KR100713103B1 (ko) * 2005-07-07 2007-05-02 씨제이 주식회사 뉴로스포라 크라사 유래 ｌ-카르니틴 생합성 관련 유전자를포함하는 엔테로박테리아세 속 미생물 및 이를 이용한ｌ-카르니틴의 제조방법
DE602005022120D1 (de) * 2005-07-19 2010-08-12 Cj Cheiljedang Corp Mikroorganismus der gattung enterobacteriacae mit genen in zusammenhang mit der biosynthese von l-carnitin sowie verfahren zur produktion von l-carnitin mit dem mikroorganismus
JP2009102258A (ja) * 2007-10-23 2009-05-14 Mitsubishi Rayon Co Ltd Ｌ−カルニチンの精製方法
JP5561506B2 (ja) * 2007-10-24 2014-07-30 三菱レイヨン株式会社 Ｌ−カルニチンの単離精製方法
TWI400223B (zh) * 2007-11-16 2013-07-01 Lonza Ag 製備甜菜鹼的方法
JP2010143857A (ja) * 2008-12-18 2010-07-01 Mitsubishi Rayon Co Ltd カルニチンの精製方法
EP2216088A1 (en) * 2009-02-04 2010-08-11 Lonza Ltd. Recovery of product losses from ED waste streams
EP2325164A1 (en) 2009-11-18 2011-05-25 Lonza Ltd. Methods for the production of l-carnitine
US8604237B2 (en) 2009-11-18 2013-12-10 Lonza Ltd Methods for the production of L-carnitine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835077B2 (ja) * 1979-05-02 1983-07-30 日東化学工業株式会社 微生物によるアクリルアミドまたはメタアクリルアミドの連続製造法
IT1142201B (it) * 1980-06-24 1986-10-08 Sigma Tau Ind Farmaceuti Procedimento per la produzione enzimatica di l-carnitina
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc Ｌ−カルニチンの製造法
DD221905B1 (de) * 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten

Also Published As

Publication number Publication date
IE860387L (en) 1987-08-27
DE3681811D1 (de) 1991-11-14
JPS61199793A (ja) 1986-09-04
CA1247549A (en) 1988-12-28
EP0195944A2 (de) 1986-10-01
EP0195944B1 (de) 1991-10-09
DK88586A (da) 1986-08-28
JP2545788B2 (ja) 1996-10-23
EP0195944A3 (en) 1987-07-29
DK166507B1 (da) 1993-06-01
ATE68211T1 (de) 1991-10-15
IE58779B1 (en) 1993-11-17
US4708936A (en) 1987-11-24
CH664374A5 (de) 1988-02-29

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Legal Events

Date Code Title Description
ATS Application withdrawn
B1 Patent granted (law 1993)
PUP Patent expired