DK673087A - Benzoxazinyl- og benzothiazinylpyridazinonforbindelser - Google Patents

Benzoxazinyl- og benzothiazinylpyridazinonforbindelser

Info

Publication number
DK673087A
DK673087A DK673087A DK673087A DK673087A DK 673087 A DK673087 A DK 673087A DK 673087 A DK673087 A DK 673087A DK 673087 A DK673087 A DK 673087A DK 673087 A DK673087 A DK 673087A
Authority
DK
Denmark
Prior art keywords
benzothiazinylpyridazinon
benzoxazinyl
compounds
benzothiazinylpyridazinon compounds
Prior art date
Application number
DK673087A
Other languages
Danish (da)
English (en)
Other versions
DK673087D0 (da
Inventor
Donald W Combs
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/944,316 external-priority patent/US4721784A/en
Priority claimed from US07/064,638 external-priority patent/US4766118A/en
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of DK673087D0 publication Critical patent/DK673087D0/da
Publication of DK673087A publication Critical patent/DK673087A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/161,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK673087A 1986-12-22 1987-12-21 Benzoxazinyl- og benzothiazinylpyridazinonforbindelser DK673087A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/944,316 US4721784A (en) 1986-12-22 1986-12-22 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
US07/064,638 US4766118A (en) 1986-12-22 1987-06-22 6-benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones and pharmaceutical use
US12514287A 1987-12-02 1987-12-02

Publications (2)

Publication Number Publication Date
DK673087D0 DK673087D0 (da) 1987-12-21
DK673087A true DK673087A (da) 1988-06-23

Family

ID=27370654

Family Applications (1)

Application Number Title Priority Date Filing Date
DK673087A DK673087A (da) 1986-12-22 1987-12-21 Benzoxazinyl- og benzothiazinylpyridazinonforbindelser

Country Status (12)

Country Link
EP (1) EP0272914A3 (pt)
KR (1) KR880007527A (pt)
AU (2) AU607731B2 (pt)
DK (1) DK673087A (pt)
FI (1) FI86425C (pt)
HU (1) HU207314B (pt)
IL (1) IL84832A (pt)
MY (2) MY106781A (pt)
NO (1) NO173653C (pt)
NZ (1) NZ222843A (pt)
PH (1) PH24498A (pt)
PT (1) PT86453B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3934436A1 (de) * 1989-06-01 1991-04-18 Thomae Gmbh Dr K 2-hydroxy-n-propylamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
TW224941B (pt) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd
US5221742A (en) * 1990-12-21 1993-06-22 Ortho Pharmaceutical Corporation Process for the preparation of 6-(3,4-dihydro-3-oxo-1,4(2h)-benzoxazin-7-yl)-2,3,4,5-tetrahydropyridazin-3-ones
AU1493092A (en) * 1991-04-18 1992-10-22 Ortho Pharmaceutical Corporation (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones
WO1997011060A1 (en) * 1995-09-22 1997-03-27 Sumitomo Chemical Company, Limited Pyrazin-2-one derivatives, their use, and intermediates for their production
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP2522670A1 (en) 2004-04-07 2012-11-14 Takeda Pharmaceutical Company Limited Heterocyclic CRF receptor antagonists
US7741317B2 (en) * 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
ZA200804550B (en) 2005-11-09 2009-08-26 Combinatorx Inc Methods, compositions, and kits for the treatment of medical conditions
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EA201391254A1 (ru) 2011-03-01 2014-02-28 Синерджи Фармасьютикалз Инк. Способ получения агонистов гуанилатциклазы c
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
EP2958577A2 (en) 2013-02-25 2015-12-30 Synergy Pharmaceuticals Inc. Guanylate cyclase receptor agonists for use in colonic cleansing
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
PT3004138T (pt) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035749A1 (pt) * 1969-02-06 1970-12-24 Bellon Labor Sa Roger
FR2588868B1 (fr) * 1985-10-21 1988-11-10 Negma Laboratoires Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant
TW224941B (pt) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd

Also Published As

Publication number Publication date
EP0272914A3 (en) 1990-04-04
NO173653C (no) 1994-01-12
NO875358L (no) 1988-06-23
FI875619A0 (fi) 1987-12-21
DK673087D0 (da) 1987-12-21
PT86453A (en) 1988-01-01
AU6808690A (en) 1991-04-26
AU633666B2 (en) 1993-02-04
FI875619A (fi) 1988-06-23
PH24498A (en) 1990-07-18
MY106781A (en) 1995-07-31
HU207314B (en) 1993-03-29
AU8293287A (en) 1988-06-23
KR880007527A (ko) 1988-08-27
FI86425C (fi) 1992-08-25
NO173653B (no) 1993-10-04
NO875358D0 (no) 1987-12-21
AU607731B2 (en) 1991-03-14
IL84832A0 (en) 1988-06-30
HUT48624A (en) 1989-06-28
FI86425B (fi) 1992-05-15
NZ222843A (en) 1989-10-27
EP0272914A2 (en) 1988-06-29
PT86453B (pt) 1990-11-20
MY102280A (en) 1992-05-15
IL84832A (en) 1993-01-14

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment