FI875619A - 6-benzoxazinyl- och 6-benzotiazonyl-2,3,4,5-tetrahydropyridazin-3-oner. - Google Patents
6-benzoxazinyl- och 6-benzotiazonyl-2,3,4,5-tetrahydropyridazin-3-oner. Download PDFInfo
- Publication number
- FI875619A FI875619A FI875619A FI875619A FI875619A FI 875619 A FI875619 A FI 875619A FI 875619 A FI875619 A FI 875619A FI 875619 A FI875619 A FI 875619A FI 875619 A FI875619 A FI 875619A
- Authority
- FI
- Finland
- Prior art keywords
- benzotiazonyl
- tetrahydropyridazin
- oner
- benzoxazinyl
- och
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94431686 | 1986-12-22 | ||
| US06/944,316 US4721784A (en) | 1986-12-22 | 1986-12-22 | 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones |
| US6463887 | 1987-06-22 | ||
| US07/064,638 US4766118A (en) | 1986-12-22 | 1987-06-22 | 6-benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones and pharmaceutical use |
| US12514287A | 1987-12-02 | 1987-12-02 | |
| US12514287 | 1987-12-02 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI875619A0 FI875619A0 (fi) | 1987-12-21 |
| FI875619A true FI875619A (fi) | 1988-06-23 |
| FI86425B FI86425B (fi) | 1992-05-15 |
| FI86425C FI86425C (fi) | 1992-08-25 |
Family
ID=27370654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI875619A FI86425C (fi) | 1986-12-22 | 1987-12-21 | Foerfarande foer framstaellning av terapeutiskt aktiva 6-benzoxazinyl- och 6-benzotiazinyl-2,3,4,5- tetrahydropyridazin-3-oner. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0272914A3 (fi) |
| KR (1) | KR880007527A (fi) |
| AU (2) | AU607731B2 (fi) |
| DK (1) | DK673087A (fi) |
| FI (1) | FI86425C (fi) |
| HU (1) | HU207314B (fi) |
| IL (1) | IL84832A (fi) |
| MY (2) | MY102280A (fi) |
| NO (1) | NO173653C (fi) |
| NZ (1) | NZ222843A (fi) |
| PH (1) | PH24498A (fi) |
| PT (1) | PT86453B (fi) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3934436A1 (de) * | 1989-06-01 | 1991-04-18 | Thomae Gmbh Dr K | 2-hydroxy-n-propylamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| TW224941B (fi) * | 1989-11-08 | 1994-06-11 | Yamanouchi Pharma Co Ltd | |
| US5221742A (en) * | 1990-12-21 | 1993-06-22 | Ortho Pharmaceutical Corporation | Process for the preparation of 6-(3,4-dihydro-3-oxo-1,4(2h)-benzoxazin-7-yl)-2,3,4,5-tetrahydropyridazin-3-ones |
| AU1493092A (en) * | 1991-04-18 | 1992-10-22 | Ortho Pharmaceutical Corporation | (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones |
| CN1202159A (zh) * | 1995-09-22 | 1998-12-16 | 住友化学工业株式会社 | 吡嗪－2－酮衍生物,它们的应用及用于制备它们的中间体 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| WO2005099688A2 (en) | 2004-04-07 | 2005-10-27 | Takeda Pharmaceutical Company Limited | Cyclic compounds |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| JP2009514969A (ja) | 2005-11-09 | 2009-04-09 | コンビナトアールエックス インコーポレーティッド | 医学的状態を治療するための方法、組成物、およびキット |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2688161C (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2522968T3 (es) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CN108676076A (zh) | 2011-03-01 | 2018-10-19 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
| US20150119399A1 (en) | 2012-01-10 | 2015-04-30 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| WO2014131024A2 (en) | 2013-02-25 | 2014-08-28 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法 |
| MX2016001714A (es) | 2013-08-09 | 2016-10-03 | Ardelyx Inc | Compuestos y metodos para inhibir el transporte de fosfato. |
| WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2035749A1 (fi) * | 1969-02-06 | 1970-12-24 | Bellon Labor Sa Roger | |
| FR2588868B1 (fr) * | 1985-10-21 | 1988-11-10 | Negma Laboratoires | Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant |
| TW224941B (fi) * | 1989-11-08 | 1994-06-11 | Yamanouchi Pharma Co Ltd |
-
1987
- 1987-12-08 NZ NZ222843A patent/NZ222843A/xx unknown
- 1987-12-15 IL IL84832A patent/IL84832A/xx unknown
- 1987-12-20 KR KR870014668A patent/KR880007527A/ko not_active Application Discontinuation
- 1987-12-21 FI FI875619A patent/FI86425C/fi not_active IP Right Cessation
- 1987-12-21 PH PH36276A patent/PH24498A/en unknown
- 1987-12-21 DK DK673087A patent/DK673087A/da not_active Application Discontinuation
- 1987-12-21 NO NO875358A patent/NO173653C/no unknown
- 1987-12-22 AU AU82932/87A patent/AU607731B2/en not_active Ceased
- 1987-12-22 PT PT86453A patent/PT86453B/pt not_active IP Right Cessation
- 1987-12-22 EP EP87311286A patent/EP0272914A3/en not_active Withdrawn
- 1987-12-22 HU HU875959A patent/HU207314B/hu not_active IP Right Cessation
- 1987-12-23 MY MYPI87003247A patent/MY102280A/en unknown
- 1987-12-23 MY MYPI91001412A patent/MY106781A/en unknown
-
1990
- 1990-12-14 AU AU68086/90A patent/AU633666B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0272914A3 (en) | 1990-04-04 |
| AU8293287A (en) | 1988-06-23 |
| AU607731B2 (en) | 1991-03-14 |
| HUT48624A (en) | 1989-06-28 |
| PT86453B (pt) | 1990-11-20 |
| NZ222843A (en) | 1989-10-27 |
| HU207314B (en) | 1993-03-29 |
| DK673087D0 (da) | 1987-12-21 |
| IL84832A0 (en) | 1988-06-30 |
| FI86425B (fi) | 1992-05-15 |
| NO173653B (no) | 1993-10-04 |
| PT86453A (en) | 1988-01-01 |
| FI875619A0 (fi) | 1987-12-21 |
| AU633666B2 (en) | 1993-02-04 |
| MY102280A (en) | 1992-05-15 |
| DK673087A (da) | 1988-06-23 |
| FI86425C (fi) | 1992-08-25 |
| EP0272914A2 (en) | 1988-06-29 |
| KR880007527A (ko) | 1988-08-27 |
| PH24498A (en) | 1990-07-18 |
| NO875358D0 (no) | 1987-12-21 |
| IL84832A (en) | 1993-01-14 |
| NO173653C (no) | 1994-01-12 |
| AU6808690A (en) | 1991-04-26 |
| NO875358L (no) | 1988-06-23 |
| MY106781A (en) | 1995-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: ORTHO PHARMACEUTICAL CORPORATION |