DK324387A - Aza-bicycliske forbindelser - Google Patents

Aza-bicycliske forbindelser

Info

Publication number
DK324387A
DK324387A DK324387A DK324387A DK324387A DK 324387 A DK324387 A DK 324387A DK 324387 A DK324387 A DK 324387A DK 324387 A DK324387 A DK 324387A DK 324387 A DK324387 A DK 324387A
Authority
DK
Denmark
Prior art keywords
aza
bicyclic
relations
bicyclic relations
Prior art date
Application number
DK324387A
Other languages
English (en)
Other versions
DK324387D0 (da
Inventor
Michael Stewart Hadley
Barry Sidney Orlek
Howard Elliott Rosenberg
Harry John Wadsworth
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK324387D0 publication Critical patent/DK324387D0/da
Publication of DK324387A publication Critical patent/DK324387A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK324387A 1986-06-27 1987-06-25 Aza-bicycliske forbindelser DK324387A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868615785A GB8615785D0 (en) 1986-06-27 1986-06-27 Compounds

Publications (2)

Publication Number Publication Date
DK324387D0 DK324387D0 (da) 1987-06-25
DK324387A true DK324387A (da) 1987-12-28

Family

ID=10600224

Family Applications (1)

Application Number Title Priority Date Filing Date
DK324387A DK324387A (da) 1986-06-27 1987-06-25 Aza-bicycliske forbindelser

Country Status (9)

Country Link
US (1) US4870081A (da)
EP (1) EP0257741A3 (da)
JP (1) JPS6339879A (da)
AU (1) AU599990B2 (da)
DK (1) DK324387A (da)
GB (1) GB8615785D0 (da)
NZ (1) NZ220840A (da)
PT (1) PT85173B (da)
ZA (1) ZA874626B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287356B1 (en) * 1987-04-15 1996-01-24 Beecham Group Plc Bridgehead substituted azabicyclic derivatives
DE68907982T2 (de) * 1988-04-15 1994-01-20 Beecham Group Plc Chemische Verbindungen.
EP0363085A3 (en) 1988-10-03 1991-03-27 Beecham Group Plc Novel compounds
CA2000041A1 (en) * 1988-10-13 1990-04-13 Barry S. Orlek Compounds
ATE269330T1 (de) * 1989-04-13 2004-07-15 Beecham Group Plc Chemische verbindungen
GB8911080D0 (en) * 1989-05-15 1989-06-28 Merck Sharp & Dohme Chemical process
YU84791A (sh) * 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklicni 1-aza-cikloalkalni
AU8436291A (en) * 1990-08-24 1992-03-17 Beecham Group Plc Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
US5356914A (en) * 1990-10-12 1994-10-18 Beecham Group P.L.C. 1,2,5,6-tetrahydropyridine oxime derivatives
HU209451B (en) * 1990-11-05 1994-06-28 Gyogyszerkutato Intezet Process for the production of 1-azabicyclo-alkan -derivatives and pharmaceutical preparations containing the same
US5244906A (en) * 1992-01-23 1993-09-14 Dowelanco Insect control with substituted oxadiazole and thiadiazole compounds
US5468875A (en) * 1994-12-22 1995-11-21 American Home Products Corporation 1-azabicycloheptane derivatives
KR19990067403A (ko) * 1995-11-08 1999-08-16 이곤 이 버그 1-아자바이시클로헵탄 유도체 및 이의 약제학적용도
US5773458A (en) * 1996-10-30 1998-06-30 American Home Products Corporation 1-azabicycloheptane derivatives
US6875774B2 (en) * 2002-08-06 2005-04-05 The University Of North Carolina Aza-bridged bicyclic amine derivatives for use as novel cholinergic receptor ligands
JP2009506069A (ja) * 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
WO2008030651A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
WO2012033956A1 (en) 2010-09-08 2012-03-15 Mithridion, Inc. Cognition enhancing compounds and compositions, methods of making, and methods of treating

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2658067A (en) * 1953-11-03 Substituted carbamic acdj esters
DE1470084A1 (de) * 1964-08-19 1969-05-29 Merck Ag E Verfahren zur Herstellung von substituierten Piperidin-derivaten
US3501471A (en) * 1966-09-21 1970-03-17 American Cyanamid Co Novel 2,3-heterocyclic fused quinuclidines,and 3-substituted quinuclidine-2-carboxylate derivatives
US3681363A (en) * 1970-08-20 1972-08-01 Univ Temple Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones
US4038402A (en) * 1974-03-05 1977-07-26 Mikhail Emmanuilovich Kaminka Method of effecting antihistaminic, antiserotonin and antiallergic actions
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
CA1223873A (en) * 1982-04-14 1987-07-07 Francis D. King Pharmaceutically active compounds
FR2526433B1 (fr) * 1982-05-04 1985-10-18 Pharmuka Lab Isomeres dextrogyres de derives de l'aza-1 bicyclo (2,2,2) octane, leur procede de preparation et medicaments les contenant
GB8518236D0 (en) * 1985-07-19 1985-08-29 Beecham Group Plc Compounds
EP0247266B1 (en) * 1986-01-07 1993-03-10 Beecham Group Plc Indole derivatives having an azabicyclic side chain, process for their preparation, intermediates, and pharmaceutical compositions
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
SE461171C (sv) * 1988-05-25 1992-08-17 Valmet Paper Machinery Inc Press med laangt nyp foer pappers- eller kartongmaskiner

Also Published As

Publication number Publication date
JPS6339879A (ja) 1988-02-20
EP0257741A3 (en) 1989-09-06
NZ220840A (en) 1990-08-28
US4870081A (en) 1989-09-26
EP0257741A2 (en) 1988-03-02
GB8615785D0 (en) 1986-08-06
DK324387D0 (da) 1987-06-25
AU7469487A (en) 1988-01-07
PT85173B (pt) 1990-03-30
PT85173A (en) 1987-07-01
ZA874626B (en) 1988-08-31
AU599990B2 (en) 1990-08-02

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment