ZA874626B - Azabicyclic compounds,process and intermediates for their preparation and pharmaceutical compositions containing them - Google Patents
Azabicyclic compounds,process and intermediates for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- ZA874626B ZA874626B ZA874626A ZA874626A ZA874626B ZA 874626 B ZA874626 B ZA 874626B ZA 874626 A ZA874626 A ZA 874626A ZA 874626 A ZA874626 A ZA 874626A ZA 874626 B ZA874626 B ZA 874626B
- Authority
- ZA
- South Africa
- Prior art keywords
- intermediates
- preparation
- pharmaceutical compositions
- compositions containing
- azabicyclic compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868615785A GB8615785D0 (en) | 1986-06-27 | 1986-06-27 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA874626B true ZA874626B (en) | 1988-08-31 |
Family
ID=10600224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA874626A ZA874626B (en) | 1986-06-27 | 1987-06-26 | Azabicyclic compounds,process and intermediates for their preparation and pharmaceutical compositions containing them |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4870081A (xx) |
| EP (1) | EP0257741A3 (xx) |
| JP (1) | JPS6339879A (xx) |
| AU (1) | AU599990B2 (xx) |
| DK (1) | DK324387A (xx) |
| GB (1) | GB8615785D0 (xx) |
| NZ (1) | NZ220840A (xx) |
| PT (1) | PT85173B (xx) |
| ZA (1) | ZA874626B (xx) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU614513B2 (en) * | 1987-04-15 | 1991-09-05 | Beecham Group Plc | 1-azabicyclic compounds |
| US5110828A (en) * | 1988-04-15 | 1992-05-05 | Beecham Group P.L.C. | Azabicyclo oxime derivatives |
| EP0363085A3 (en) | 1988-10-03 | 1991-03-27 | Beecham Group Plc | Novel compounds |
| CA2000041A1 (en) * | 1988-10-13 | 1990-04-13 | Barry S. Orlek | Compounds |
| DK0392803T3 (da) * | 1989-04-13 | 2004-10-18 | Beecham Group Plc | Hidtil ukendte forbindelser |
| GB8911080D0 (en) * | 1989-05-15 | 1989-06-28 | Merck Sharp & Dohme | Chemical process |
| YU84791A (xx) * | 1990-05-19 | 1994-06-10 | Boehringer Ingelheim Kg. | Biciklični 1-aza-cikloalkalni |
| EP0544773B1 (en) * | 1990-08-24 | 1998-03-18 | Beecham Group Plc | Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them |
| GB9019095D0 (en) * | 1990-09-01 | 1990-10-17 | Beecham Group Plc | Novel compounds |
| JPH06501933A (ja) * | 1990-10-12 | 1994-03-03 | ビーチャム・グループ・パブリック・リミテッド・カンパニー | １，２，５，６−テトラヒドロピリジン・オキシム誘導体 |
| HU209451B (en) * | 1990-11-05 | 1994-06-28 | Gyogyszerkutato Intezet | Process for the production of 1-azabicyclo-alkan -derivatives and pharmaceutical preparations containing the same |
| US5244906A (en) * | 1992-01-23 | 1993-09-14 | Dowelanco | Insect control with substituted oxadiazole and thiadiazole compounds |
| US5468875A (en) * | 1994-12-22 | 1995-11-21 | American Home Products Corporation | 1-azabicycloheptane derivatives |
| KR19990067403A (ko) * | 1995-11-08 | 1999-08-16 | 이곤 이 버그 | 1-아자바이시클로헵탄 유도체 및 이의 약제학적용도 |
| US5773458A (en) * | 1996-10-30 | 1998-06-30 | American Home Products Corporation | 1-azabicycloheptane derivatives |
| US6875774B2 (en) | 2002-08-06 | 2005-04-05 | The University Of North Carolina | Aza-bridged bicyclic amine derivatives for use as novel cholinergic receptor ligands |
| EP2275095A3 (en) * | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| WO2012033956A1 (en) | 2010-09-08 | 2012-03-15 | Mithridion, Inc. | Cognition enhancing compounds and compositions, methods of making, and methods of treating |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2658067A (en) * | 1953-11-03 | Substituted carbamic acdj esters | ||
| DE1470084A1 (de) * | 1964-08-19 | 1969-05-29 | Merck Ag E | Verfahren zur Herstellung von substituierten Piperidin-derivaten |
| US3501471A (en) * | 1966-09-21 | 1970-03-17 | American Cyanamid Co | Novel 2,3-heterocyclic fused quinuclidines,and 3-substituted quinuclidine-2-carboxylate derivatives |
| US3681363A (en) * | 1970-08-20 | 1972-08-01 | Univ Temple | Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones |
| US4038402A (en) * | 1974-03-05 | 1977-07-26 | Mikhail Emmanuilovich Kaminka | Method of effecting antihistaminic, antiserotonin and antiallergic actions |
| US4203990A (en) * | 1979-04-30 | 1980-05-20 | G. D. Searle & Co. | Anti-diarrheal 2-substituted quinuclidines |
| IE56226B1 (en) * | 1982-04-14 | 1991-05-22 | Beecham Group Plc | Substituted azabicyclo compounds,process for their preparation and pharmaceutical compositions containing them |
| FR2526433B1 (fr) * | 1982-05-04 | 1985-10-18 | Pharmuka Lab | Isomeres dextrogyres de derives de l'aza-1 bicyclo (2,2,2) octane, leur procede de preparation et medicaments les contenant |
| GB8518236D0 (en) * | 1985-07-19 | 1985-08-29 | Beecham Group Plc | Compounds |
| DE3687980T2 (de) * | 1986-01-07 | 1993-06-17 | Beecham Group Plc | Indolderivate mit einer azabicyclischen seitenkette, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zusammensetzungen. |
| NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
| SE461171C (sv) * | 1988-05-25 | 1992-08-17 | Valmet Paper Machinery Inc | Press med laangt nyp foer pappers- eller kartongmaskiner |
-
1986
- 1986-06-27 GB GB868615785A patent/GB8615785D0/en active Pending
-
1987
- 1987-06-23 EP EP87305585A patent/EP0257741A3/en not_active Ceased
- 1987-06-25 DK DK324387A patent/DK324387A/da not_active Application Discontinuation
- 1987-06-25 PT PT85173A patent/PT85173B/pt not_active IP Right Cessation
- 1987-06-25 AU AU74694/87A patent/AU599990B2/en not_active Ceased
- 1987-06-25 NZ NZ220840A patent/NZ220840A/xx unknown
- 1987-06-26 JP JP62159483A patent/JPS6339879A/ja active Pending
- 1987-06-26 US US07/067,364 patent/US4870081A/en not_active Expired - Fee Related
- 1987-06-26 ZA ZA874626A patent/ZA874626B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0257741A3 (en) | 1989-09-06 |
| JPS6339879A (ja) | 1988-02-20 |
| PT85173B (pt) | 1990-03-30 |
| PT85173A (en) | 1987-07-01 |
| DK324387A (da) | 1987-12-28 |
| NZ220840A (en) | 1990-08-28 |
| AU7469487A (en) | 1988-01-07 |
| US4870081A (en) | 1989-09-26 |
| GB8615785D0 (en) | 1986-08-06 |
| DK324387D0 (da) | 1987-06-25 |
| AU599990B2 (en) | 1990-08-02 |
| EP0257741A2 (en) | 1988-03-02 |
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