DK633389A - Chimer, omdannende vaekstfaktor beta1/beta2, nucleotidsekvens indeholdende den, celle og cellelinie indeholdende sekvensen samt fremgangsmaade til vaekstfaktorfremstilling - Google Patents

Chimer, omdannende vaekstfaktor beta1/beta2, nucleotidsekvens indeholdende den, celle og cellelinie indeholdende sekvensen samt fremgangsmaade til vaekstfaktorfremstilling Download PDF

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Publication number
DK633389A
DK633389A DK633389A DK633389A DK633389A DK 633389 A DK633389 A DK 633389A DK 633389 A DK633389 A DK 633389A DK 633389 A DK633389 A DK 633389A DK 633389 A DK633389 A DK 633389A
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sequence
cell
chimer
beta1
beta2
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DK633389A
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Danish (da)
English (en)
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DK633389D0 (da
Inventor
Anthony F Purchio
Linda Madisen
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Oncogen
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Publication of DK633389D0 publication Critical patent/DK633389D0/da
Publication of DK633389A publication Critical patent/DK633389A/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
DK633389A 1988-12-15 1989-12-14 Chimer, omdannende vaekstfaktor beta1/beta2, nucleotidsekvens indeholdende den, celle og cellelinie indeholdende sekvensen samt fremgangsmaade til vaekstfaktorfremstilling DK633389A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28497288A 1988-12-15 1988-12-15

Publications (2)

Publication Number Publication Date
DK633389D0 DK633389D0 (da) 1989-12-14
DK633389A true DK633389A (da) 1990-06-16

Family

ID=23092228

Family Applications (1)

Application Number Title Priority Date Filing Date
DK633389A DK633389A (da) 1988-12-15 1989-12-14 Chimer, omdannende vaekstfaktor beta1/beta2, nucleotidsekvens indeholdende den, celle og cellelinie indeholdende sekvensen samt fremgangsmaade til vaekstfaktorfremstilling

Country Status (18)

Country Link
US (1) US5244793A (ja)
EP (1) EP0374044B1 (ja)
JP (1) JPH0335794A (ja)
KR (1) KR900009983A (ja)
CN (1) CN1045994A (ja)
AT (1) ATE111520T1 (ja)
AU (1) AU634733B2 (ja)
CA (1) CA2005120A1 (ja)
DE (1) DE68918248T2 (ja)
DK (1) DK633389A (ja)
ES (1) ES2063834T3 (ja)
FI (1) FI97299C (ja)
HU (1) HUT52550A (ja)
IE (1) IE66571B1 (ja)
IL (1) IL92669A (ja)
NO (1) NO300464B1 (ja)
PT (1) PT92603B (ja)
ZA (1) ZA899517B (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304541A (en) * 1988-12-15 1994-04-19 Bristol-Myers Squibb Company Methods using novel chimeric transforming growth factor-β1/β2
CA2003886A1 (en) * 1988-12-16 1990-06-16 Anthony F. Purchio Cloning and expression of simian transforming growth factor-beta 1
US5169764A (en) * 1990-08-08 1992-12-08 Regeneron Pharmaceuticals, Inc. Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
GB9106678D0 (en) * 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
AU2738392A (en) * 1991-11-11 1993-05-13 Ciba-Geigy Ag Novel hybrid transforming growth factors
IT1259042B (it) * 1992-01-27 1996-03-11 Mini Ricerca Scient Tecnolog Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5420243A (en) * 1993-01-26 1995-05-30 Celtrix Pharmaceuticals, Inc. Biologically active TGF-β2 peptides
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
WO1994026303A1 (en) * 1993-05-13 1994-11-24 Neorx Corporation Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
AU6959898A (en) 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
US20030175257A1 (en) * 2002-03-12 2003-09-18 Song Sun Uk Cartilage regeneration using chondrocyte and TGF-beta

Also Published As

Publication number Publication date
HUT52550A (en) 1990-07-28
EP0374044B1 (en) 1994-09-14
PT92603A (pt) 1990-06-29
HU896613D0 (en) 1990-02-28
IE893984L (en) 1990-06-15
NO300464B1 (no) 1997-06-02
FI895935A0 (fi) 1989-12-12
CA2005120A1 (en) 1990-06-15
FI97299B (fi) 1996-08-15
IL92669A (en) 1997-02-18
NO895028L (no) 1990-06-18
CN1045994A (zh) 1990-10-10
NO895028D0 (no) 1989-12-14
ZA899517B (en) 1990-09-26
AU4683489A (en) 1990-06-21
KR900009983A (ko) 1990-07-06
US5244793A (en) 1993-09-14
JPH0335794A (ja) 1991-02-15
EP0374044A3 (en) 1991-07-31
PT92603B (pt) 1995-09-12
ES2063834T3 (es) 1995-01-16
EP0374044A2 (en) 1990-06-20
ATE111520T1 (de) 1994-09-15
DE68918248T2 (de) 1995-05-04
FI97299C (fi) 1996-11-25
DE68918248D1 (de) 1994-10-20
IE66571B1 (en) 1996-01-24
IL92669A0 (en) 1990-08-31
AU634733B2 (en) 1993-03-04
DK633389D0 (da) 1989-12-14

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