DK61890A - Fremgangsmaade til bestemmelse af antigener ved hjaelp af to eller flere monoklonale antistoffer - Google Patents

Fremgangsmaade til bestemmelse af antigener ved hjaelp af to eller flere monoklonale antistoffer Download PDF

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Publication number
DK61890A
DK61890A DK061890A DK61890A DK61890A DK 61890 A DK61890 A DK 61890A DK 061890 A DK061890 A DK 061890A DK 61890 A DK61890 A DK 61890A DK 61890 A DK61890 A DK 61890A
Authority
DK
Denmark
Prior art keywords
antigenes
procedure
determining
monoclonal antibodies
monoclonal
Prior art date
Application number
DK061890A
Other languages
English (en)
Other versions
DK61890D0 (da
DK163840B (da
DK163840C (da
Inventor
Anna Maria Gezina Bosch
Antonius Hermanus Wilh Schuurs
Wilhelmus Johannes Hen Stevens
Bauke Klaas Van Weemen
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19835673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK61890(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK61890A publication Critical patent/DK61890A/da
Publication of DK61890D0 publication Critical patent/DK61890D0/da
Publication of DK163840B publication Critical patent/DK163840B/da
Application granted granted Critical
Publication of DK163840C publication Critical patent/DK163840C/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G01N33/541—Double or second antibody, i.e. precipitating antibody
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/968—Plasmin, i.e. fibrinolysin
DK061890A 1980-07-28 1990-03-08 Fremgangsmaade til bestemmelse af antigener ved hjaelp af to eller flere monoklonale antistoffer og proeveudstyr til brug ved fremgangsmaaden DK163840C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NLAANVRAGE8004308,A NL185309C (nl) 1980-07-28 1980-07-28 Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.
NL8004308 1980-07-28

Publications (4)

Publication Number Publication Date
DK61890A true DK61890A (da) 1990-03-08
DK61890D0 DK61890D0 (da) 1990-03-08
DK163840B DK163840B (da) 1992-04-06
DK163840C DK163840C (da) 1992-08-24

Family

ID=19835673

Family Applications (3)

Application Number Title Priority Date Filing Date
DK315081A DK163838B (da) 1980-07-28 1981-07-15 Fremgangsmaade til bestemmelse af antigener ved hjaelp af to monoklonale antistoffer og et proeveudstyr til brug ved denne fremgangsmaade
DK061890A DK163840C (da) 1980-07-28 1990-03-08 Fremgangsmaade til bestemmelse af antigener ved hjaelp af to eller flere monoklonale antistoffer og proeveudstyr til brug ved fremgangsmaaden
DK061990A DK163839C (da) 1980-07-28 1990-03-08 Fremgangsmaade til bestemmelse af antigener ved hjaelp af tre eller flere monoklonale antistoffer, og et proeveudstyr til brug ved fremgangsmaaden

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK315081A DK163838B (da) 1980-07-28 1981-07-15 Fremgangsmaade til bestemmelse af antigener ved hjaelp af to monoklonale antistoffer og et proeveudstyr til brug ved denne fremgangsmaade

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK061990A DK163839C (da) 1980-07-28 1990-03-08 Fremgangsmaade til bestemmelse af antigener ved hjaelp af tre eller flere monoklonale antistoffer, og et proeveudstyr til brug ved fremgangsmaaden

Country Status (8)

Country Link
US (1) US6391563B1 (da)
EP (1) EP0045103B1 (da)
JP (2) JPS5786051A (da)
AU (1) AU549077B2 (da)
DE (1) DE3167698D1 (da)
DK (3) DK163838B (da)
ES (1) ES504285A0 (da)
NL (3) NL185309C (da)

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US6406920B1 (en) 1980-06-20 2002-06-18 Inverness Medical Switzerland Gmbh Processes and apparatus for carrying out specific binding assays
JPH0235944B2 (ja) * 1980-06-20 1990-08-14 Unilever Nv Tokuitekiketsugokenteiojitsushisuruhohooyobigaihohoojitsushisurutamenoshikenkitsuto
EP0111762B1 (en) * 1980-06-20 1987-11-19 Unilever Plc Processes and apparatus for carrying out specific binding assays
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4879219A (en) * 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US4837167A (en) * 1981-01-30 1989-06-06 Centocor, Inc. Immunoassay for multi-determinant antigens using high-affinity
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク　インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
JPS58127167A (ja) * 1982-01-26 1983-07-28 Green Cross Corp:The 逆受身モノクロ−ナル抗体赤血球凝集反応用抗原検出試薬
GB2118300B (en) * 1982-02-12 1985-06-19 Corning Glass Works Method of immunoassay
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
JPS5954966A (ja) * 1982-09-22 1984-03-29 Mochida Pharmaceut Co Ltd 免疫学的測定試薬
JPS6080768A (ja) * 1983-10-12 1985-05-08 Eisai Co Ltd 塩基性胎児蛋白の測定方法および試薬
US4595661A (en) * 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
US4690890A (en) * 1984-04-04 1987-09-01 Cetus Corporation Process for simultaneously detecting multiple antigens using dual sandwich immunometric assay
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
JPH0736016B2 (ja) * 1984-05-11 1995-04-19 和光純薬工業株式会社 免疫グロブリンの定量方法
US4707438A (en) * 1984-08-22 1987-11-17 Tel Aviv University Immunoassay for breast cancer employing monoclonal antibodies
US4654298A (en) * 1984-10-05 1987-03-31 Abbott Laboratories Method for detection of peritoneal inflammation or infection
US4845197A (en) * 1985-09-09 1989-07-04 Agri-Diagnostics Associates Monoclonal antibodies and methods for fungal pathogen detection
JPH07119762B2 (ja) * 1986-04-09 1995-12-20 和光純薬工業株式会社 補体の定量方法
JP2591750B2 (ja) * 1986-06-26 1997-03-19 オ−ソ・ダイアグノステイツク・システムズ・インコ−ポレ−テツド 免疫分析システム
US5187067A (en) * 1986-12-15 1993-02-16 Teijin Limited Immunological determination of free human protein S and C4bp-protein S complex
DE3789284T2 (de) * 1986-12-15 1994-07-14 Teijin Ltd Immunologische Bestimmung von freiem menschlichem Protein-S und c4bp-Protein-S-Komplex.
US5179000A (en) * 1987-07-24 1993-01-12 Nippon Kayaku Kabushiki Kaisha Method for assaying basic fetoprotein in urine and assay kit therefor
DK546988A (da) * 1987-10-02 1989-04-03 Du Pont Immunobestemmelse og reagenssaet til anvendesle herved
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
JPH01301165A (ja) * 1988-05-30 1989-12-05 Sekisui Chem Co Ltd 免疫測定法
DE3929119A1 (de) * 1989-09-01 1991-03-07 Boehringer Mannheim Gmbh Verfahren zum nachweis von analyten
JPH03118472A (ja) * 1989-09-29 1991-05-21 Sekisui Chem Co Ltd インスリン定量方法及び定量試薬
US5447846A (en) * 1992-07-17 1995-09-05 Fuji Photo Film C., Ltd. Homogeneous Immunoassay process using covalent conjugate of enzyme and plural monoclonal antibodies for different epitopes on analyte
JP2709296B2 (ja) * 1996-05-27 1998-02-04 オリンパス光学工業株式会社 免疫学的分析方法
JP3652029B2 (ja) * 1996-10-16 2005-05-25 積水化学工業株式会社 高感度免疫測定法
EP2042870A1 (en) * 2007-09-28 2009-04-01 Fujifilm Corporation Method of high sensitive immunoassay
GB0820999D0 (en) * 2008-11-17 2008-12-24 Menon Johansson Anatole S Pregnancy testing
JP7313659B2 (ja) * 2019-03-12 2023-07-25 株式会社シノテスト 試料中のｈｍｇｂ１の測定方法及び測定試薬

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
ZA783261B (en) * 1977-06-15 1979-06-27 Wistar Inst Method of producing antibodies
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4115535A (en) * 1977-06-22 1978-09-19 General Electric Company Diagnostic method employing a mixture of normally separable protein-coated particles
US4191739A (en) * 1977-10-17 1980-03-04 General Electric Company Antigen-antibody reaction assay employing particle aggregation and resistive pulse analysis
US4244940A (en) * 1978-09-05 1981-01-13 Bio-Rad Laboratories, Inc. Single-incubation two-site immunoassay
DE3177290T2 (de) * 1980-04-09 1993-04-15 British Tech Group Monoklonale antikoerper gegen hepatitis-b-virus.
CH642458A5 (en) * 1980-04-25 1984-04-13 Hoffmann La Roche Immunological method
US4361647A (en) * 1980-05-22 1982-11-30 Palo Alto Medical Research Foundation Sandwich immunoassay and compositions for use therein
JPH0235944B2 (ja) * 1980-06-20 1990-08-14 Unilever Nv Tokuitekiketsugokenteiojitsushisuruhohooyobigaihohoojitsushisurutamenoshikenkitsuto
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies

Also Published As

Publication number Publication date
DK163839C (da) 1992-08-24
AU7307881A (en) 1982-02-04
NL185309C (nl) 1990-03-01
NL186407C (nl) 1990-11-16
NL188869B (nl) 1992-05-18
DK61890D0 (da) 1990-03-08
DK163840B (da) 1992-04-06
ES8206856A1 (es) 1982-08-16
DK163839B (da) 1992-04-06
DK61990D0 (da) 1990-03-08
NL8702776A (nl) 1988-03-01
DE3167698D1 (en) 1985-01-24
US6391563B1 (en) 2002-05-21
NL8004308A (nl) 1982-03-01
JPH0340341B2 (da) 1991-06-18
NL8702777A (nl) 1988-03-01
DK163840C (da) 1992-08-24
DK61990A (da) 1990-03-08
JPS5786051A (en) 1982-05-28
DK163838B (da) 1992-04-06
EP0045103B1 (en) 1984-12-12
NL186407B (nl) 1990-06-18
AU549077B2 (en) 1986-01-16
NL185309B (nl) 1989-10-02
EP0045103A3 (en) 1982-02-10
JPH06258325A (ja) 1994-09-16
ES504285A0 (es) 1982-08-16
EP0045103A2 (en) 1982-02-03
DK315081A (da) 1982-01-29

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