NL185309C - Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens. - Google Patents

Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.

Info

Publication number
NL185309C
NL185309C NLAANVRAGE8004308,A NL8004308A NL185309C NL 185309 C NL185309 C NL 185309C NL 8004308 A NL8004308 A NL 8004308A NL 185309 C NL185309 C NL 185309C
Authority
NL
Netherlands
Prior art keywords
monoclonal antibodies
immune reagents
determining antigens
antigens
determining
Prior art date
Application number
NLAANVRAGE8004308,A
Other languages
English (en)
Dutch (nl)
Other versions
NL8004308A (nl
NL185309B (nl
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19835673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL185309(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nv filed Critical Akzo Nv
Priority to NLAANVRAGE8004308,A priority Critical patent/NL185309C/xx
Priority to DE8181200768T priority patent/DE3167698D1/de
Priority to EP81200768A priority patent/EP0045103B1/en
Priority to DK315081A priority patent/DK163838B/da
Priority to AU73078/81A priority patent/AU549077B2/en
Priority to JP56116313A priority patent/JPS5786051A/ja
Priority to ES504285A priority patent/ES8206856A1/es
Publication of NL8004308A publication Critical patent/NL8004308A/nl
Priority to NLAANVRAGE8702777,A priority patent/NL186407C/xx
Priority to NLAANVRAGE8702776,A priority patent/NL188869B/xx
Publication of NL185309B publication Critical patent/NL185309B/xx
Publication of NL185309C publication Critical patent/NL185309C/xx
Application granted granted Critical
Priority to DK061890A priority patent/DK163840C/da
Priority to DK061990A priority patent/DK163839C/da
Priority to JP3114174A priority patent/JPH06258325A/ja
Priority to US08/164,581 priority patent/US6391563B1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G01N33/541—Double or second antibody, i.e. precipitating antibody
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/968—Plasmin, i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NLAANVRAGE8004308,A 1980-07-28 1980-07-28 Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens. NL185309C (nl)

Priority Applications (13)

Application Number Priority Date Filing Date Title
NLAANVRAGE8004308,A NL185309C (nl) 1980-07-28 1980-07-28 Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.
DE8181200768T DE3167698D1 (en) 1980-07-28 1981-07-06 Method for the determination of antigens with the aid of two or more monoclonal antibodies
EP81200768A EP0045103B1 (en) 1980-07-28 1981-07-06 Method for the determination of antigens with the aid of two or more monoclonal antibodies
DK315081A DK163838B (da) 1980-07-28 1981-07-15 Fremgangsmaade til bestemmelse af antigener ved hjaelp af to monoklonale antistoffer og et proeveudstyr til brug ved denne fremgangsmaade
AU73078/81A AU549077B2 (en) 1980-07-28 1981-07-17 Determination of antigens with monoclonal antibodies
ES504285A ES8206856A1 (es) 1980-07-28 1981-07-24 Mejoras en un metodo y su correspondiente equipo de ensayo para determinar antigenos por medio de una reaccion inmuno- quimica
JP56116313A JPS5786051A (en) 1980-07-28 1981-07-24 Determination of antigen employing two or more monochronal antibodies
NLAANVRAGE8702777,A NL186407C (nl) 1980-07-28 1987-11-20 Methode voor het bepalen van antigenen met behulp van drie verschillende soorten monoklonale antilichamen alsmede testverpakking voor deze bepaling.
NLAANVRAGE8702776,A NL188869B (nl) 1980-07-28 1987-11-20 Methode voor het bepalen van antigenen, alsmede testkit daarvoor.
DK061890A DK163840C (da) 1980-07-28 1990-03-08 Fremgangsmaade til bestemmelse af antigener ved hjaelp af to eller flere monoklonale antistoffer og proeveudstyr til brug ved fremgangsmaaden
DK061990A DK163839C (da) 1980-07-28 1990-03-08 Fremgangsmaade til bestemmelse af antigener ved hjaelp af tre eller flere monoklonale antistoffer, og et proeveudstyr til brug ved fremgangsmaaden
JP3114174A JPH06258325A (ja) 1980-07-28 1991-02-22 異なる２又は３種類のモノクローナル抗体を使用する 抗原測定法及び該モノクローナル抗体を利用した試験 キット
US08/164,581 US6391563B1 (en) 1980-07-28 1993-12-08 Method for the determination of antigens with the aid of three or more monoclonal antibodies

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8004308 1980-07-28
NLAANVRAGE8004308,A NL185309C (nl) 1980-07-28 1980-07-28 Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.

Publications (3)

Publication Number Publication Date
NL8004308A NL8004308A (nl) 1982-03-01
NL185309B NL185309B (nl) 1989-10-02
NL185309C true NL185309C (nl) 1990-03-01

Family

ID=19835673

Family Applications (3)

Application Number Title Priority Date Filing Date
NLAANVRAGE8004308,A NL185309C (nl) 1980-07-28 1980-07-28 Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.
NLAANVRAGE8702777,A NL186407C (nl) 1980-07-28 1987-11-20 Methode voor het bepalen van antigenen met behulp van drie verschillende soorten monoklonale antilichamen alsmede testverpakking voor deze bepaling.
NLAANVRAGE8702776,A NL188869B (nl) 1980-07-28 1987-11-20 Methode voor het bepalen van antigenen, alsmede testkit daarvoor.

Family Applications After (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE8702777,A NL186407C (nl) 1980-07-28 1987-11-20 Methode voor het bepalen van antigenen met behulp van drie verschillende soorten monoklonale antilichamen alsmede testverpakking voor deze bepaling.
NLAANVRAGE8702776,A NL188869B (nl) 1980-07-28 1987-11-20 Methode voor het bepalen van antigenen, alsmede testkit daarvoor.

Country Status (8)

Country Link
US (1) US6391563B1 (xx)
EP (1) EP0045103B1 (xx)
JP (2) JPS5786051A (xx)
AU (1) AU549077B2 (xx)
DE (1) DE3167698D1 (xx)
DK (3) DK163838B (xx)
ES (1) ES8206856A1 (xx)
NL (3) NL185309C (xx)

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US2952816A (en) * 1955-10-21 1960-09-13 Gen Electric Limiting amplifier
EP0146654A3 (en) * 1980-06-20 1986-08-20 Unilever Plc Processes and apparatus for carrying out specific binding assays
US6406920B1 (en) 1980-06-20 2002-06-18 Inverness Medical Switzerland Gmbh Processes and apparatus for carrying out specific binding assays
JPH0235944B2 (ja) * 1980-06-20 1990-08-14 Unilever Nv Tokuitekiketsugokenteiojitsushisuruhohooyobigaihohoojitsushisurutamenoshikenkitsuto
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4879219A (en) * 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US4837167A (en) * 1981-01-30 1989-06-06 Centocor, Inc. Immunoassay for multi-determinant antigens using high-affinity
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク　インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
JPS58127167A (ja) * 1982-01-26 1983-07-28 Green Cross Corp:The 逆受身モノクロ−ナル抗体赤血球凝集反応用抗原検出試薬
GB2118300B (en) * 1982-02-12 1985-06-19 Corning Glass Works Method of immunoassay
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
JPS5954966A (ja) * 1982-09-22 1984-03-29 Mochida Pharmaceut Co Ltd 免疫学的測定試薬
JPS6080768A (ja) * 1983-10-12 1985-05-08 Eisai Co Ltd 塩基性胎児蛋白の測定方法および試薬
US4595661A (en) * 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
US4690890A (en) * 1984-04-04 1987-09-01 Cetus Corporation Process for simultaneously detecting multiple antigens using dual sandwich immunometric assay
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
JPH0736016B2 (ja) * 1984-05-11 1995-04-19 和光純薬工業株式会社 免疫グロブリンの定量方法
US4707438A (en) * 1984-08-22 1987-11-17 Tel Aviv University Immunoassay for breast cancer employing monoclonal antibodies
US4654298A (en) * 1984-10-05 1987-03-31 Abbott Laboratories Method for detection of peritoneal inflammation or infection
US4845197A (en) * 1985-09-09 1989-07-04 Agri-Diagnostics Associates Monoclonal antibodies and methods for fungal pathogen detection
JPH07119762B2 (ja) * 1986-04-09 1995-12-20 和光純薬工業株式会社 補体の定量方法
JP2591750B2 (ja) * 1986-06-26 1997-03-19 オ−ソ・ダイアグノステイツク・システムズ・インコ−ポレ−テツド 免疫分析システム
US5187067A (en) * 1986-12-15 1993-02-16 Teijin Limited Immunological determination of free human protein S and C4bp-protein S complex
EP0271810B1 (en) * 1986-12-15 1994-03-09 Teijin Limited Immunological determination of free human protein s and c4bp-protein s complex
US5179000A (en) * 1987-07-24 1993-01-12 Nippon Kayaku Kabushiki Kaisha Method for assaying basic fetoprotein in urine and assay kit therefor
NO884368L (no) * 1987-10-02 1989-04-03 Du Pont Immunanalyse ved anvendelse av igg-innfangelsesantistoff og multippel, monoklonalt antistoffpaavisningssystem.
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
JPH01301165A (ja) * 1988-05-30 1989-12-05 Sekisui Chem Co Ltd 免疫測定法
DE3929119A1 (de) * 1989-09-01 1991-03-07 Boehringer Mannheim Gmbh Verfahren zum nachweis von analyten
JPH03118472A (ja) * 1989-09-29 1991-05-21 Sekisui Chem Co Ltd インスリン定量方法及び定量試薬
US5447846A (en) * 1992-07-17 1995-09-05 Fuji Photo Film C., Ltd. Homogeneous Immunoassay process using covalent conjugate of enzyme and plural monoclonal antibodies for different epitopes on analyte
JP2709296B2 (ja) * 1996-05-27 1998-02-04 オリンパス光学工業株式会社 免疫学的分析方法
JP3652029B2 (ja) * 1996-10-16 2005-05-25 積水化学工業株式会社 高感度免疫測定法
EP2042870A1 (en) * 2007-09-28 2009-04-01 Fujifilm Corporation Method of high sensitive immunoassay
GB0820999D0 (en) * 2008-11-17 2008-12-24 Menon Johansson Anatole S Pregnancy testing
JP7313659B2 (ja) * 2019-03-12 2023-07-25 株式会社シノテスト 試料中のｈｍｇｂ１の測定方法及び測定試薬

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US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
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US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4115535A (en) * 1977-06-22 1978-09-19 General Electric Company Diagnostic method employing a mixture of normally separable protein-coated particles
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US4361647A (en) * 1980-05-22 1982-11-30 Palo Alto Medical Research Foundation Sandwich immunoassay and compositions for use therein
JPH0235944B2 (ja) * 1980-06-20 1990-08-14 Unilever Nv Tokuitekiketsugokenteiojitsushisuruhohooyobigaihohoojitsushisurutamenoshikenkitsuto
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies

Also Published As

Publication number Publication date
DE3167698D1 (en) 1985-01-24
EP0045103A3 (en) 1982-02-10
NL8702776A (nl) 1988-03-01
DK163840C (da) 1992-08-24
DK61990A (da) 1990-03-08
DK163839B (da) 1992-04-06
DK315081A (da) 1982-01-29
DK61890D0 (da) 1990-03-08
ES504285A0 (es) 1982-08-16
EP0045103A2 (en) 1982-02-03
US6391563B1 (en) 2002-05-21
NL8702777A (nl) 1988-03-01
NL186407B (nl) 1990-06-18
AU549077B2 (en) 1986-01-16
DK163838B (da) 1992-04-06
NL186407C (nl) 1990-11-16
DK61890A (da) 1990-03-08
NL8004308A (nl) 1982-03-01
NL185309B (nl) 1989-10-02
ES8206856A1 (es) 1982-08-16
DK163840B (da) 1992-04-06
JPH0340341B2 (xx) 1991-06-18
EP0045103B1 (en) 1984-12-12
DK61990D0 (da) 1990-03-08
JPS5786051A (en) 1982-05-28
DK163839C (da) 1992-08-24
AU7307881A (en) 1982-02-04
JPH06258325A (ja) 1994-09-16
NL188869B (nl) 1992-05-18

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