DK596083A - Carboxylsyreamidderivat, fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende en saadan forbindelse - Google Patents

Carboxylsyreamidderivat, fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende en saadan forbindelse Download PDF

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Publication number
DK596083A
DK596083A DK596083A DK596083A DK596083A DK 596083 A DK596083 A DK 596083A DK 596083 A DK596083 A DK 596083A DK 596083 A DK596083 A DK 596083A DK 596083 A DK596083 A DK 596083A
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DK
Denmark
Prior art keywords
procedures
preparing
compound
carboxylic acid
acid amide
Prior art date
Application number
DK596083A
Other languages
Danish (da)
English (en)
Other versions
DK596083D0 (da
Inventor
Yasuji Harigaya
Hiroo Ogura
Mitsuo Mihara
Motosuke Yamanaka
Kiyomi Yamatsu
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of DK596083D0 publication Critical patent/DK596083D0/da
Publication of DK596083A publication Critical patent/DK596083A/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/59—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK596083A 1982-12-27 1983-12-23 Carboxylsyreamidderivat, fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende en saadan forbindelse DK596083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57226685A JPS59118750A (ja) 1982-12-27 1982-12-27 カルボン酸アミド化合物およびその誘導体

Publications (2)

Publication Number Publication Date
DK596083D0 DK596083D0 (da) 1983-12-23
DK596083A true DK596083A (da) 1984-06-28

Family

ID=16849045

Family Applications (1)

Application Number Title Priority Date Filing Date
DK596083A DK596083A (da) 1982-12-27 1983-12-23 Carboxylsyreamidderivat, fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende en saadan forbindelse

Country Status (18)

Country Link
US (1) US4661630A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS59118750A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR840007714A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2253183A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE898570A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1202312A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH656875A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3346814A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK596083A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES528409A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2538386B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2133006B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU189799B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1170275B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8304406A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH19459A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE8307119L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA839546B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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JPS59231057A (ja) * 1983-06-14 1984-12-25 Eisai Co Ltd カルボン酸アミド化合物およびその誘導体
DE3334822A1 (de) * 1983-09-26 1985-04-04 Bayer Ag, 5090 Leverkusen Neue flammschutzmittel, ihre herstellung und ihre verwendung zur flammfestausruestung von polycarbonaten
HUP0303172A3 (en) 2000-06-28 2006-05-29 Bristol Myers Squibb Co Selective androgen receptor modulators and methods for their identification, desing and use
US20040077605A1 (en) 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
CN100370975C (zh) * 2000-12-18 2008-02-27 株式会社医药分子设计研究所 炎症性细胞因子产生游离抑制剂
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
MXPA04000224A (es) 2001-07-10 2005-07-25 4Sc Ag Novedosos compuestos como agentes antiinflamatorios, inmunomoduladores y antiproliferativos.
HUP0500096A3 (en) 2001-12-19 2012-08-28 Bristol Myers Squibb Co Fused heterocyclic compounds and analogs thereof: modulators of nuclear hormone receptor function, process for producing them and pharmaceutical compositions containing them
DE10222895A1 (de) * 2002-05-23 2003-12-11 Bosch Gmbh Robert Hochdruckspeicher für Kraftstoffeinspritzsysteme mit integriertem Druckregelventil
WO2003103648A1 (ja) * 2002-06-05 2003-12-18 株式会社医薬分子設計研究所 糖尿病治療薬
EP1510210A4 (en) * 2002-06-05 2009-01-07 Inst Med Molecular Design Inc IMMUNITY-CONTAINING PROTEIN KINASE HEMMER
AU2003242127A1 (en) * 2002-06-05 2003-12-22 Institute Of Medicinal Molecular Design, Inc. Inhibitors against the activation of ap-1 and nfat
EA009701B1 (ru) * 2002-06-06 2008-02-28 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Противоаллергические средства
AU2003242118B2 (en) * 2002-06-06 2008-09-11 Institute Of Medicinal Molecular Design, Inc O-substituted hydroxyaryl derivatives
AU2003242098B2 (en) * 2002-06-10 2008-11-20 Institute Of Medicinal Molecular Design, Inc Inhibitors against activation of NFkappaB
TW200307535A (en) * 2002-06-10 2003-12-16 Inst Med Molecular Design Inc Therapeutic agent for cancer
CN100490793C (zh) * 2002-06-11 2009-05-27 株式会社医药分子设计研究所 神经变性疾病治疗药
EP1561978B1 (en) * 2002-11-12 2008-04-09 Nok Corporation Rubber-like elastic part
US7247736B2 (en) * 2002-12-23 2007-07-24 4Sc Ag Method of identifying inhibitors of DHODH
WO2004056746A1 (en) * 2002-12-23 2004-07-08 4Sc Ag Cycloalkene dicarboxylic acid compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
EP1581478A1 (en) * 2002-12-23 2005-10-05 4Sc Ag Dhodh-inhibitors and method for their identification
US7365094B2 (en) 2002-12-23 2008-04-29 4Sc Ag Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
ATE450498T1 (de) * 2002-12-23 2009-12-15 4Sc Ag Cycloalken-dicarbonsäure-verbindungen als entzündungshemmende, immunmodulatorische und antiproliferative mittel
EP1541198A1 (en) * 2003-12-05 2005-06-15 4Sc Ag Cycloalkyl compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
EP2585054A1 (en) 2010-06-24 2013-05-01 Allergan, Inc. Derivatives of cycloalkyl- and cycloalkenyl-1,2-dicarboxylic acid compounds having formyl peptide receptor like-1 (fprl-1) agonist or antagonist activity
UA108760C2 (uk) 2010-07-01 2015-06-10 Кальцієві солі сполуки як протизапальні, імуномодулюючі та антипроліферативні засоби
EP4438591A1 (en) 2018-03-16 2024-10-02 Immunic AG Novel calcium salt polymorphs as anti-inflammatory, immunomodulatory and anti-proliferatory agents
EP4057782A1 (en) 2021-03-12 2022-09-14 Atotech Deutschland GmbH & Co. KG Method for increasing adhesion strength between copper and an organic material and reducing halo and wedge void formation by modifying the copper surface and/or by using heteroaromatic silane compounds
EP4056285A1 (en) 2021-03-12 2022-09-14 Atotech Deutschland GmbH & Co. KG Triazine silane compound and its usage as adhesion promotor

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JPS59231057A (ja) * 1983-06-14 1984-12-25 Eisai Co Ltd カルボン酸アミド化合物およびその誘導体

Also Published As

Publication number Publication date
DE3346814A1 (de) 1984-06-28
US4661630A (en) 1987-04-28
PH19459A (en) 1986-04-18
BE898570A (fr) 1984-06-27
NL8304406A (nl) 1984-07-16
GB8333713D0 (en) 1984-01-25
HU189799B (en) 1986-07-28
IT1170275B (it) 1987-06-03
ES8601859A1 (es) 1985-11-01
ES8608486A1 (es) 1986-06-16
GB2133006B (en) 1986-10-22
JPS59118750A (ja) 1984-07-09
DK596083D0 (da) 1983-12-23
CH656875A5 (de) 1986-07-31
SE8307119L (sv) 1984-06-28
IT8324351A0 (it) 1983-12-23
CA1202312A (en) 1986-03-25
FR2538386B1 (fr) 1986-04-18
AU2253183A (en) 1984-07-05
JPH0136819B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-08-02
ZA839546B (en) 1984-08-29
ES543810A0 (es) 1986-06-16
SE8307119D0 (sv) 1983-12-22
FR2538386A1 (fr) 1984-06-29
KR840007714A (ko) 1984-12-10
GB2133006A (en) 1984-07-18
ES528409A0 (es) 1985-11-01

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