DK587788D0 - Fremgangsmaade til fremstilling af et humant faktor ix koncentrat og andre plasmaproteiner samt terapeutisk anvendelse deraf - Google Patents

Fremgangsmaade til fremstilling af et humant faktor ix koncentrat og andre plasmaproteiner samt terapeutisk anvendelse deraf

Info

Publication number
DK587788D0
DK587788D0 DK587788A DK587788A DK587788D0 DK 587788 D0 DK587788 D0 DK 587788D0 DK 587788 A DK587788 A DK 587788A DK 587788 A DK587788 A DK 587788A DK 587788 D0 DK587788 D0 DK 587788D0
Authority
DK
Denmark
Prior art keywords
concentrate
preparing
procedure
human factor
plasma proteins
Prior art date
Application number
DK587788A
Other languages
English (en)
Other versions
DK173859B1 (da
DK587788A (da
Inventor
Thierry Burnouf
Catherine Michalski
Original Assignee
Centre Regional De Transfusion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26226280&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK587788(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR8714665A external-priority patent/FR2622108B1/fr
Priority claimed from FR8806923A external-priority patent/FR2631830B1/fr
Application filed by Centre Regional De Transfusion filed Critical Centre Regional De Transfusion
Publication of DK587788D0 publication Critical patent/DK587788D0/da
Publication of DK587788A publication Critical patent/DK587788A/da
Application granted granted Critical
Publication of DK173859B1 publication Critical patent/DK173859B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/647Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK198805877A 1987-10-23 1988-10-21 Fremgangsmåde til fremstilling af et højrenset humant faktor IX koncentrat og andre plasmaproteiner DK173859B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8714665A FR2622108B1 (fr) 1987-10-23 1987-10-23 Preparation de concentres de proconvertine (facteur vii), de facteur antihemophilique b (facteur ix) et d'autres proteines plasmatiques, et leur utilisation therapeutique
FR8714665 1987-10-23
FR8806923A FR2631830B1 (fr) 1988-05-25 1988-05-25 Concentre de facteur ix de haute purete, sa preparation et son utilisation en therapeutique
FR8806923 1988-05-25

Publications (3)

Publication Number Publication Date
DK587788D0 true DK587788D0 (da) 1988-10-21
DK587788A DK587788A (da) 1989-04-24
DK173859B1 DK173859B1 (da) 2001-12-31

Family

ID=26226280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198805877A DK173859B1 (da) 1987-10-23 1988-10-21 Fremgangsmåde til fremstilling af et højrenset humant faktor IX koncentrat og andre plasmaproteiner

Country Status (8)

Country Link
US (1) US5457181A (da)
EP (1) EP0317376B2 (da)
JP (1) JP2768957B2 (da)
DE (1) DE3877529T2 (da)
DK (1) DK173859B1 (da)
ES (1) ES2045167T5 (da)
GR (2) GR3006910T3 (da)
NO (1) NO179997C (da)

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AU671586B2 (en) 1991-03-01 1996-09-05 Aventis Behring Llc Preparation of factor IX
FR2711371B1 (fr) * 1993-10-18 1995-12-29 Aetsrn Procédé de préparation d'un concentré d'inter-alpha-trypsine inhibiteur à usage thérapeutique et concentré obtenu.
DE4342132C1 (de) * 1993-12-10 1994-11-03 Octapharma Ag Verfahren zur Herstellung virusinaktivierte Vitamin K abhängige Plasmakomponenten sowie Protein C und Protein S enthaltender Mittel durch Membran-Chromatographie
DE4406515C1 (de) * 1994-02-28 1995-10-19 Immuno Ag Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine
US6372716B1 (en) 1994-04-26 2002-04-16 Genetics Institute, Inc. Formulations for factor IX
DE4435520A1 (de) * 1994-10-04 1996-04-11 Immuno Ag Verfahren zur Trennung von rekombinantem pro-Faktor IX von rekombinantem Faktor IX
DE19504852C2 (de) * 1995-02-15 2003-01-23 Octapharma Ag Lachen Verfahren zur Reinigung Vitamin K-abhängiger Gerinnungsfaktoren durch Affinitäts-Chromatographie
DE19506633A1 (de) * 1995-02-25 1996-08-29 Octapharma Ag Verfahren zur Herstellung von Faktor IX aus biologischen Quellen
US5714583A (en) 1995-06-07 1998-02-03 Genetics Institute, Inc. Factor IX purification methods
US5770700A (en) * 1996-01-25 1998-06-23 Genetics Institute, Inc. Liquid factor IX formulations
ES2127695B1 (es) * 1997-02-14 2000-03-16 Grifols Grupo Sa Procedimiento para la reduccion del contenido de factor plaquetar 4 en proteinas plasmaticas que poseen afinidad a heparina.
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
BR0215216A (pt) 2001-12-21 2004-11-16 Novo Nordisk Healthcare Ag Composição aquosa lìquida, método para preparar uma composição aquosa lìquida de um polipeptìdeo de fator vii, uso de uma composição aquosa lìquida, e, método para o tratamento de uma sìndrome de resposta ao fator vii
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
BRPI0311959B8 (pt) 2002-06-21 2021-05-25 Novo Nordisk Healthcare Ag composição, métodos para preparar um polipeptídeo estável do fator vii, e para tratar uma síndrome responsiva do fator vii, e, uso do polipeptídeo do fator vii
SE0203551D0 (sv) * 2002-12-02 2002-12-02 Biovitrum Ab Prothrombin purification
US20040106779A1 (en) * 2002-12-03 2004-06-03 Bigler Douglas E. Modified factor IX preparation
AT501088A2 (de) * 2002-12-18 2006-06-15 Bio Prod & Bio Eng Ag Stabile therapeutische proteine
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
KR20060015574A (ko) * 2003-05-23 2006-02-17 노보 노르디스크 헬스 케어 악티엔게젤샤프트 용액 중 단백질 안정화
WO2005002615A1 (en) * 2003-07-01 2005-01-13 Novo Nordisk Health Care Ag Liquid, aqueous pharmaceutical composition of factor vii polypeptides
CN102872451A (zh) * 2003-08-14 2013-01-16 诺和诺德医疗保健公司 因子vii多肽类的含水液体药物组合物
JP4855074B2 (ja) * 2003-09-30 2012-01-18 一般財団法人化学及血清療法研究所 高純度血液凝固ix因子調製物およびその精製方法
KR20150138427A (ko) * 2003-12-19 2015-12-09 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 vii 폴리펩티드의 안정화된 조성물
EP1755652B1 (en) * 2004-03-19 2010-11-24 Baxter International Inc. Factor ixa for the treatment of bleeding disorders
KR100667860B1 (ko) 2005-10-18 2007-01-11 주식회사 녹십자 고순도 사람 혈액응고 제9인자의 정제 방법
EP2059258B1 (en) * 2006-09-08 2019-11-13 Wyeth LLC Arginine wash in protein purification using affinity chromatography
EP2125866B1 (en) * 2007-02-28 2013-05-22 Baxter International Inc. Method for the purification of recombinant blood coagulation factor ix enriched in sulfated and/or phosphorylated molecules
ES2595059T3 (es) 2007-03-20 2016-12-27 Csl Behring Gmbh Métodos para la producción a escala industrial de preparados terapéuticos del Factor H del complemento a partir de plasma humano
KR20130124507A (ko) * 2010-11-16 2013-11-14 옥타파마 아게 응고 인자 FXI 및 FXIa를 함유한 용액으로부터 FXI 및 FXIa를 감소시키고 및/또는 제거하는 방법
AU2011343813B2 (en) 2010-12-15 2015-05-21 Takeda Pharmaceutical Company Limited Eluate collection using conductivity gradient
LT2748179T (lt) 2011-10-14 2022-04-11 Takeda Pharmaceutical Company Limited Baltymų gryninimas anijonų mainų chromatografija
US20140206844A1 (en) 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma
GB201506117D0 (en) * 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
GB201506113D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
CN110339209B (zh) * 2019-07-18 2023-06-06 上海泰坦科技股份有限公司 一种去甲状腺结合蛋白的小牛血清的制备方法

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US4374763A (en) * 1979-09-17 1983-02-22 Morishita Pharmaceutical Co., Ltd. Method for producing gamma-globulin for use in intravenous administration and method for producing a pharmaceutical preparation thereof
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DE3172210D1 (en) * 1980-05-27 1985-10-17 Miles Lab Blood coagulation promoting product and process of preparing same
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US4447416A (en) * 1982-04-28 1984-05-08 American National Red Cross Plasma protein concentrates of reduced thrombogenicity and their use in clinical replacement therapy
US4397841A (en) * 1982-06-28 1983-08-09 Monsanto Company Production of blood coagulation factor VIII:C
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
DE3336631A1 (de) * 1983-10-08 1985-04-18 Behringwerke Ag, 3550 Marburg Verfahren zur pasteurisierung von plasma oder von konzentraten der blutgerinnungsfaktoren ii, vii, ix und x
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CA1288711C (en) * 1986-01-06 1991-09-10 Kenneth J. Smith Therapeutic blood product means and methods of preparing same

Also Published As

Publication number Publication date
EP0317376B1 (fr) 1993-01-13
US5457181A (en) 1995-10-10
GR3006910T3 (en) 1993-06-30
DK173859B1 (da) 2001-12-31
NO179997C (no) 1997-01-29
DK587788A (da) 1989-04-24
NO884688D0 (no) 1988-10-21
NO884688L (no) 1989-04-24
ES2045167T3 (es) 1994-01-16
JP2768957B2 (ja) 1998-06-25
NO179997B (no) 1996-10-21
GR3019900T3 (en) 1996-08-31
DE3877529D1 (de) 1993-02-25
ES2045167T5 (es) 1996-07-01
JPH01207239A (ja) 1989-08-21
EP0317376A1 (fr) 1989-05-24
DE3877529T2 (de) 1996-11-07
EP0317376B2 (fr) 1996-04-03

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired