DK529276A - Fremgangsmade til fremstilling af sus fremgangsmade til fremstilling af sustituerede imidazo-(1,2-a)-pyridiner - Google Patents

Fremgangsmade til fremstilling af sus fremgangsmade til fremstilling af sustituerede imidazo-(1,2-a)-pyridiner

Info

Publication number
DK529276A
DK529276A DK529276A DK529276A DK529276A DK 529276 A DK529276 A DK 529276A DK 529276 A DK529276 A DK 529276A DK 529276 A DK529276 A DK 529276A DK 529276 A DK529276 A DK 529276A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
sustituted
pyridines
imidazo
Prior art date
Application number
DK529276A
Other languages
Danish (da)
English (en)
Inventor
R J Bochis
P Kulsa
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK529276A publication Critical patent/DK529276A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86Hydrazides; Thio or imino analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK529276A 1975-12-09 1976-11-24 Fremgangsmade til fremstilling af sus fremgangsmade til fremstilling af sustituerede imidazo-(1,2-a)-pyridiner DK529276A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63903475A 1975-12-09 1975-12-09

Publications (1)

Publication Number Publication Date
DK529276A true DK529276A (da) 1977-06-10

Family

ID=24562456

Family Applications (1)

Application Number Title Priority Date Filing Date
DK529276A DK529276A (da) 1975-12-09 1976-11-24 Fremgangsmade til fremstilling af sus fremgangsmade til fremstilling af sustituerede imidazo-(1,2-a)-pyridiner

Country Status (25)

Country Link
US (1) US4096264A (US06299757-20011009-C00006.png)
JP (1) JPS5273896A (US06299757-20011009-C00006.png)
AR (1) AR222960A1 (US06299757-20011009-C00006.png)
AT (1) AT361475B (US06299757-20011009-C00006.png)
AU (1) AU505045B2 (US06299757-20011009-C00006.png)
BE (1) BE849123A (US06299757-20011009-C00006.png)
CA (1) CA1084930A (US06299757-20011009-C00006.png)
CH (1) CH626362A5 (US06299757-20011009-C00006.png)
DE (1) DE2655681A1 (US06299757-20011009-C00006.png)
DK (1) DK529276A (US06299757-20011009-C00006.png)
ES (1) ES453947A1 (US06299757-20011009-C00006.png)
FI (1) FI763343A (US06299757-20011009-C00006.png)
FR (1) FR2334357A1 (US06299757-20011009-C00006.png)
GB (1) GB1524589A (US06299757-20011009-C00006.png)
GR (1) GR62009B (US06299757-20011009-C00006.png)
IL (1) IL51024A (US06299757-20011009-C00006.png)
NL (1) NL7613160A (US06299757-20011009-C00006.png)
NO (1) NO764025L (US06299757-20011009-C00006.png)
NZ (1) NZ182756A (US06299757-20011009-C00006.png)
OA (1) OA05506A (US06299757-20011009-C00006.png)
PH (1) PH12259A (US06299757-20011009-C00006.png)
PL (1) PL103751B1 (US06299757-20011009-C00006.png)
PT (1) PT65915B (US06299757-20011009-C00006.png)
SE (1) SE430504B (US06299757-20011009-C00006.png)
ZA (1) ZA767331B (US06299757-20011009-C00006.png)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
US4154835A (en) * 1977-10-12 1979-05-15 Merck & Co., Inc. Anthelmintic imidazo [1,2-a] pyridines
US4250174A (en) * 1979-05-02 1981-02-10 Merck & Co., Inc. 3-Substituted imidazo [1,2-A] pyridines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
US4507481A (en) * 1983-07-29 1985-03-26 Pennwalt Corporation Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines
IT1173196B (it) * 1984-02-02 1987-06-18 Bellon Roger Schoum Rbs Pharma Composti imidazopiridinici farmacologicamente attivi
US5214138A (en) * 1989-12-20 1993-05-25 Case Western Reserve University Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same
US5244908A (en) * 1990-07-30 1993-09-14 Takeda Chemical Industries, Ltd. Imidazopyridine derivatives and their pharmaceutical use
WO1999059587A1 (en) * 1998-05-20 1999-11-25 Eli Lilly And Company Anti-viral compounds
US6358971B1 (en) 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
DE10117184A1 (de) * 2001-04-05 2002-10-17 Gruenenthal Gmbh Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen
JP2007529496A (ja) * 2004-03-19 2007-10-25 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 抗菌剤としてのイミダゾピリジン及びイミダゾピリミジン誘導体
DE602005020313D1 (de) * 2004-08-12 2010-05-12 Amgen Inc Bisaryl-sulfonamide
US8304557B2 (en) * 2007-06-05 2012-11-06 Takeda Pharmaceutical Company Limited Fused heterocycle derivatives and use thereof
US8431608B2 (en) 2007-08-17 2013-04-30 Icagen Inc. Heterocycles as potassium channel modulators
US8058274B2 (en) * 2007-08-17 2011-11-15 Icagen, Inc. Heterocycles as potassium channel modulators
JP5270553B2 (ja) * 2007-08-23 2013-08-21 武田薬品工業株式会社 複素環化合物およびその用途
WO2009028629A1 (ja) * 2007-08-29 2009-03-05 Takeda Pharmaceutical Company Limited 複素環化合物およびその用途
EP2444403A1 (en) 2008-04-18 2012-04-25 Shionogi Co., Ltd. Heterocyclic compound having inhibitory activity on PI3K
US8445509B2 (en) * 2008-05-08 2013-05-21 Takeda Pharmaceutical Company Limited Fused heterocyclic derivatives and use thereof
EP2399921B1 (en) * 2008-12-01 2015-08-12 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
JO3101B1 (ar) 2008-12-02 2017-09-20 Takeda Pharmaceuticals Co مشتقات بنزوثيازول كعوامل مضادة للسرطان
US9567318B2 (en) 2009-08-17 2017-02-14 Memorial Sloan-Kettering Cancer Center Substituted pyrimidine compounds and uses thereof
KR102461419B1 (ko) 2014-05-13 2022-11-02 메모리얼 슬로안 케터링 캔서 센터 Hsp70 조정물질 및 이의 제조 및 이용 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701780A (en) * 1970-09-18 1972-10-31 Merck & Co Inc Imidazo(1,2-a)pyridines
JPS5124517B1 (US06299757-20011009-C00006.png) * 1971-03-15 1976-07-24

Also Published As

Publication number Publication date
CA1084930A (en) 1980-09-02
US4096264A (en) 1978-06-20
DE2655681A1 (de) 1977-06-16
FR2334357B1 (US06299757-20011009-C00006.png) 1982-10-15
PL103751B1 (pl) 1979-07-31
JPS6126545B2 (US06299757-20011009-C00006.png) 1986-06-20
NZ182756A (en) 1979-11-01
BE849123A (fr) 1977-06-07
PT65915A (en) 1977-01-01
GB1524589A (en) 1978-09-13
PT65915B (en) 1978-11-07
ES453947A1 (es) 1978-03-01
GR62009B (en) 1979-02-15
NO764025L (US06299757-20011009-C00006.png) 1977-06-10
PH12259A (en) 1978-12-12
FR2334357A1 (fr) 1977-07-08
FI763343A (US06299757-20011009-C00006.png) 1977-06-10
AU505045B2 (en) 1979-11-08
IL51024A0 (en) 1977-01-31
JPS5273896A (en) 1977-06-21
CH626362A5 (US06299757-20011009-C00006.png) 1981-11-13
ATA901876A (de) 1980-08-15
AR222960A1 (es) 1981-07-15
AT361475B (de) 1981-03-10
SE7613128L (sv) 1977-06-10
NL7613160A (nl) 1977-06-13
OA05506A (fr) 1981-04-30
ZA767331B (en) 1978-07-26
IL51024A (en) 1981-12-31
SE430504B (sv) 1983-11-21
AU2010276A (en) 1978-06-08

Similar Documents

Publication Publication Date Title
DK529276A (da) Fremgangsmade til fremstilling af sus fremgangsmade til fremstilling af sustituerede imidazo-(1,2-a)-pyridiner
DK146626C (da) Analogifremgangsmaade til fremstilling af 4'-deoxydaunomycin
DK282076A (da) Fremgangsmade til fremstilling af 2,3-dihydro6,7-disubstitueret-5-acyl-benzofuran-2-carboxylsyrer
DK136655B (da) Analogifremgangsmåde til fremstilling af piperazinyliminorifamyciner.
DK107876A (da) Fremgangsmade til fremstilling af thiocarbamider
DK164376A (da) Fremgangsmade til fremstilling af 3,4-dihydrospiro-2h-1,3-benzoxaziner
DK554076A (da) Fremgangsmade til fremstilling af 3,4i-dideoxykanamycin ]
DK273776A (da) Fremgangsmade til fremstilling af 2,4-dioxo-1,2,3,4-tetrahydro-s-triazino-(1,2-a)-benzimidazoler
DK148139C (da) Analogifremgangsmaade til fremstilling af 5-benzyl-2-oxazolidonderivater
DK150676A (da) Fremgangsmade til fremstilling af krystallinsk natrium-o-formyl-cefamandol
DK139969B (da) Analogifremgangsmåde til fremstilling af 1-alkylcarbamoyl-5-fluoruraciler.
DK185977A (da) Fremgangsmade til fremstilling af 1,3-dihydroheteroarylspiro (isobenzofuraner)
DK136656B (da) Analogifremgangsmåde til fremstilling af substituerede piperazinyliminorifamyciner.
DK143757C (da) Analogifremgangsmaade til fremstilling af 16,16-disubstituerede 3-oxoandrostener
DK146629C (da) Analogifremgangsmaade til fremstilling af depotsteroidestere
DK399976A (da) Fremgangsmade til fremstilling af aralkylamider
DK415576A (da) Fremgangsmade til fremstilling af krystallinsk dipilocarpiniumpamoat
DK140502B (da) Analogifremgangsmåde til fremstilling af triazolobenzocycloalkylthiadiaziner.
DK141584C (da) Fremgangsmaade til fremstilling af slagseje vinylaromat-podecopolymere
DK424676A (da) Fremgangsmade til fremstilling af 2-alkylindan
DK480676A (da) Fremgangsmade til fremstilling af s-alkylphosphordihalogeniddithioater
DK149803C (da) Fremgangsmaade til fremstilling af 1,2-dichlorethan
DK544476A (da) Fremgangsmade til fremstilling af difluormethyl-1,2,2-trifluorethylether
DK305076A (da) Fremgangsmade til fremstilling af d,l-pantolacton
DK46476A (da) Fremgangsmade til fremstilling af 5-nitrothiazolylimidazolidiner

Legal Events

Date Code Title Description
ATS Application withdrawn