DK527187A - Gonadoliberin-analoge, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler - Google Patents
Gonadoliberin-analoge, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidlerInfo
- Publication number
- DK527187A DK527187A DK527187A DK527187A DK527187A DK 527187 A DK527187 A DK 527187A DK 527187 A DK527187 A DK 527187A DK 527187 A DK527187 A DK 527187A DK 527187 A DK527187 A DK 527187A
- Authority
- DK
- Denmark
- Prior art keywords
- trp
- preparation
- thi
- phe
- optionally substituted
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical compound OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 2
- QIVBCDIJIAJPQS-SECBINFHSA-N D-tryptophane Chemical compound C1=CC=C2C(C[C@@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-SECBINFHSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- HQMLIDZJXVVKCW-UWTATZPHSA-N (2r)-2-aminopropanamide Chemical compound C[C@@H](N)C(N)=O HQMLIDZJXVVKCW-UWTATZPHSA-N 0.000 abstract 1
- -1 Aza-Gly-NH2 Chemical compound 0.000 abstract 1
- 125000000734 D-serino group Chemical group [H]N([H])[C@@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical compound NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003147 glycosyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cosmetics (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3634435 | 1986-10-09 | ||
DE19863634435 DE3634435A1 (de) | 1986-10-09 | 1986-10-09 | Analoga von gonadoliberin mit verbesserter loeslichkeit, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung |
Publications (3)
Publication Number | Publication Date |
---|---|
DK527187D0 DK527187D0 (da) | 1987-10-08 |
DK527187A true DK527187A (da) | 1988-04-10 |
DK171823B1 DK171823B1 (da) | 1997-06-23 |
Family
ID=6311399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK527187A DK171823B1 (da) | 1986-10-09 | 1987-10-08 | Gonadoliberin-analoge peptider og farmaceutisk acceptable salte deraf, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler |
Country Status (20)
Country | Link |
---|---|
US (1) | US5091367A (da) |
EP (1) | EP0263521B1 (da) |
JP (1) | JP2573625B2 (da) |
KR (1) | KR960013387B1 (da) |
AT (1) | ATE70278T1 (da) |
AU (1) | AU595383B2 (da) |
CA (1) | CA1314656C (da) |
CZ (1) | CZ408491A3 (da) |
DE (2) | DE3634435A1 (da) |
DK (1) | DK171823B1 (da) |
ES (1) | ES2055696T3 (da) |
FI (1) | FI86863C (da) |
GR (1) | GR3003927T3 (da) |
IE (1) | IE60296B1 (da) |
IL (1) | IL84121A (da) |
NZ (1) | NZ222076A (da) |
PH (1) | PH24731A (da) |
PT (1) | PT85881B (da) |
SK (1) | SK408491A3 (da) |
ZA (1) | ZA877561B (da) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2218102B (en) * | 1988-04-08 | 1992-09-16 | Sandoz Ltd | Calcitonin peptide derivatives |
DE3842010A1 (de) * | 1988-12-14 | 1990-06-21 | Hoechst Ag | Kompetitive gonadoliberin-antagonisten |
DE59100945D1 (de) * | 1990-08-04 | 1994-03-10 | Hoechst Ag | Gonadoliberin-Antagonisten. |
US5760000A (en) * | 1994-05-13 | 1998-06-02 | University Technologies International,Inc. | Inhibition of liver cancer by the use of GnRH and GnRH analogs |
GB2343182A (en) * | 1998-10-27 | 2000-05-03 | Ferring Bv | Use of GnRH-II and analogues thereof for the treatment of osteoporosis |
CN1301771A (zh) * | 1999-12-27 | 2001-07-04 | 上海博德基因开发有限公司 | 一种新的多肽——人促性腺释放激素11和编码这种多肽的多核苷酸 |
CN1315354A (zh) * | 2000-03-24 | 2001-10-03 | 上海博德基因开发有限公司 | 一种新的多肽——人促性腺释放激素12和编码这种多肽的多核苷酸 |
US7803764B2 (en) * | 2004-03-29 | 2010-09-28 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Amphipathic glycopeptides |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ188987A (en) * | 1977-11-30 | 1982-02-23 | Salk Inst For Biological Studi | Peptide analogues of luteinizing hormone releasing factor |
FR2465486A1 (fr) * | 1979-09-21 | 1981-03-27 | Roussel Uclaf | Nouvelle application utilisant la lh-rh ou des agonistes |
US4409208A (en) * | 1980-04-15 | 1983-10-11 | The Salk Institute For Biological Studies | GnRH antagonists |
US4444759A (en) * | 1982-07-26 | 1984-04-24 | The Salk Institute For Biological Studies | GnRH Antagonists II |
EP0145032B1 (en) * | 1983-08-16 | 1987-11-04 | Akzo N.V. | Lh- rh antagonists |
-
1986
- 1986-10-09 DE DE19863634435 patent/DE3634435A1/de not_active Withdrawn
-
1987
- 1987-10-06 KR KR1019870011124A patent/KR960013387B1/ko not_active IP Right Cessation
- 1987-10-07 FI FI874401A patent/FI86863C/fi not_active IP Right Cessation
- 1987-10-07 IL IL84121A patent/IL84121A/xx not_active IP Right Cessation
- 1987-10-07 PH PH35901A patent/PH24731A/en unknown
- 1987-10-07 NZ NZ222076A patent/NZ222076A/xx unknown
- 1987-10-08 JP JP62252637A patent/JP2573625B2/ja not_active Expired - Lifetime
- 1987-10-08 DK DK527187A patent/DK171823B1/da not_active IP Right Cessation
- 1987-10-08 IE IE269387A patent/IE60296B1/en not_active IP Right Cessation
- 1987-10-08 ES ES87114702T patent/ES2055696T3/es not_active Expired - Lifetime
- 1987-10-08 DE DE8787114702T patent/DE3775156D1/de not_active Expired - Fee Related
- 1987-10-08 AU AU79459/87A patent/AU595383B2/en not_active Ceased
- 1987-10-08 AT AT87114702T patent/ATE70278T1/de not_active IP Right Cessation
- 1987-10-08 ZA ZA877561A patent/ZA877561B/xx unknown
- 1987-10-08 EP EP87114702A patent/EP0263521B1/de not_active Expired - Lifetime
- 1987-10-08 CA CA000548918A patent/CA1314656C/en not_active Expired - Fee Related
- 1987-10-08 PT PT85881A patent/PT85881B/pt unknown
-
1991
- 1991-06-28 US US07/724,477 patent/US5091367A/en not_active Expired - Fee Related
- 1991-12-27 SK SK4084-91A patent/SK408491A3/sk unknown
- 1991-12-27 CZ CS914084A patent/CZ408491A3/cs unknown
-
1992
- 1992-02-28 GR GR910402214T patent/GR3003927T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA1314656C (en) | 1993-03-16 |
IL84121A (en) | 1992-06-21 |
IL84121A0 (en) | 1988-03-31 |
ATE70278T1 (de) | 1991-12-15 |
US5091367A (en) | 1992-02-25 |
AU7945987A (en) | 1988-04-14 |
FI86863C (fi) | 1992-10-26 |
ES2055696T3 (es) | 1994-09-01 |
IE872693L (en) | 1988-04-09 |
FI874401A0 (fi) | 1987-10-07 |
DE3634435A1 (de) | 1988-04-14 |
ZA877561B (en) | 1988-05-25 |
DK527187D0 (da) | 1987-10-08 |
SK408491A3 (en) | 1995-07-11 |
FI874401A (fi) | 1988-04-10 |
KR880005149A (ko) | 1988-06-28 |
DE3775156D1 (de) | 1992-01-23 |
EP0263521A2 (de) | 1988-04-13 |
JPS6396198A (ja) | 1988-04-27 |
GR3003927T3 (da) | 1993-03-16 |
PH24731A (en) | 1990-10-01 |
JP2573625B2 (ja) | 1997-01-22 |
PT85881B (pt) | 1990-07-31 |
EP0263521B1 (de) | 1991-12-11 |
CZ408491A3 (en) | 1993-01-13 |
IE60296B1 (en) | 1994-06-29 |
EP0263521A3 (en) | 1988-07-06 |
FI86863B (fi) | 1992-07-15 |
PT85881A (de) | 1987-11-01 |
KR960013387B1 (ko) | 1996-10-04 |
NZ222076A (en) | 1989-09-27 |
AU595383B2 (en) | 1990-03-29 |
DK171823B1 (da) | 1997-06-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |
Country of ref document: DK |