PT98533A - Processo para a preparacao de antagonistas de gonadoliberinas e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de antagonistas de gonadoliberinas e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT98533A PT98533A PT98533A PT9853391A PT98533A PT 98533 A PT98533 A PT 98533A PT 98533 A PT98533 A PT 98533A PT 9853391 A PT9853391 A PT 9853391A PT 98533 A PT98533 A PT 98533A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- phe
- contain
- pharmaceutical compositions
- trp
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 102000009165 Gonadoliberin Human genes 0.000 title 1
- 108050000048 Gonadoliberin Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical compound OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 3
- QIVBCDIJIAJPQS-SECBINFHSA-N D-tryptophane Chemical compound C1=CC=C2C(C[C@@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-SECBINFHSA-N 0.000 abstract 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
- HQMLIDZJXVVKCW-UWTATZPHSA-N (2r)-2-aminopropanamide Chemical compound C[C@@H](N)C(N)=O HQMLIDZJXVVKCW-UWTATZPHSA-N 0.000 abstract 1
- 125000000734 D-serino group Chemical group [H]N([H])[C@@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 abstract 1
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 abstract 1
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 abstract 1
- 102000009151 Luteinizing Hormone Human genes 0.000 abstract 1
- 108010073521 Luteinizing Hormone Proteins 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical compound NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 229960003604 testosterone Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4024779 | 1990-08-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT98533A true PT98533A (pt) | 1992-06-30 |
| PT98533B PT98533B (pt) | 1999-01-29 |
Family
ID=6411646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98533A PT98533B (pt) | 1990-08-04 | 1991-08-01 | Processo para a preparacao de antagonistas de gonadoliberinas e de composicoes farmaceuticas que os contem |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5434138A (pt) |
| EP (1) | EP0477499B1 (pt) |
| JP (1) | JP3164844B2 (pt) |
| KR (1) | KR100191700B1 (pt) |
| AT (1) | ATE100822T1 (pt) |
| AU (1) | AU641035B2 (pt) |
| CA (1) | CA2048407C (pt) |
| DE (1) | DE59100945D1 (pt) |
| DK (1) | DK0477499T3 (pt) |
| ES (1) | ES2062628T3 (pt) |
| IE (1) | IE65965B1 (pt) |
| IL (1) | IL99062A (pt) |
| NO (1) | NO309429B1 (pt) |
| NZ (1) | NZ239233A (pt) |
| PT (1) | PT98533B (pt) |
| TW (1) | TW205046B (pt) |
| ZA (1) | ZA916097B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5691314A (en) * | 1996-03-18 | 1997-11-25 | The Medical College Of Hampton Roads | Adjunctive therapy |
| CN1301771A (zh) * | 1999-12-27 | 2001-07-04 | 上海博德基因开发有限公司 | 一种新的多肽——人促性腺释放激素11和编码这种多肽的多核苷酸 |
| US11805833B1 (en) * | 2019-05-10 | 2023-11-07 | Julie Vahos | Flexible hair extension with form retention capability |
| WO2023101490A1 (ko) * | 2021-12-01 | 2023-06-08 | 애니젠 주식회사 | 가니렐릭스의 신규한 제조방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54148722A (en) * | 1978-05-12 | 1979-11-21 | Takeda Chem Ind Ltd | Nonapeptide and its preparation |
| US5073624A (en) * | 1985-04-09 | 1991-12-17 | Administrators Of The Tulane Educational Fund | Therapeutic decapeptides |
| US4661472A (en) * | 1985-05-09 | 1987-04-28 | The Salk Institute For Biological Studies | GnRH antagonists IX |
| DE3634435A1 (de) * | 1986-10-09 | 1988-04-14 | Hoechst Ag | Analoga von gonadoliberin mit verbesserter loeslichkeit, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung |
| US4801577A (en) * | 1987-02-05 | 1989-01-31 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists |
| US5110904A (en) * | 1989-08-07 | 1992-05-05 | Abbott Laboratories | Lhrh analogs |
| GB2218102B (en) * | 1988-04-08 | 1992-09-16 | Sandoz Ltd | Calcitonin peptide derivatives |
-
1991
- 1991-07-30 AT AT91112817T patent/ATE100822T1/de not_active IP Right Cessation
- 1991-07-30 ES ES91112817T patent/ES2062628T3/es not_active Expired - Lifetime
- 1991-07-30 EP EP91112817A patent/EP0477499B1/de not_active Expired - Lifetime
- 1991-07-30 DK DK91112817.1T patent/DK0477499T3/da active
- 1991-07-30 DE DE91112817T patent/DE59100945D1/de not_active Expired - Fee Related
- 1991-08-01 PT PT98533A patent/PT98533B/pt not_active IP Right Cessation
- 1991-08-02 IL IL9906291A patent/IL99062A/en not_active IP Right Cessation
- 1991-08-02 AU AU81548/91A patent/AU641035B2/en not_active Ceased
- 1991-08-02 NZ NZ239233A patent/NZ239233A/xx unknown
- 1991-08-02 KR KR1019910013368A patent/KR100191700B1/ko not_active IP Right Cessation
- 1991-08-02 NO NO913020A patent/NO309429B1/no unknown
- 1991-08-02 ZA ZA916097A patent/ZA916097B/xx unknown
- 1991-08-02 CA CA002048407A patent/CA2048407C/en not_active Expired - Fee Related
- 1991-08-02 IE IE276991A patent/IE65965B1/en not_active IP Right Cessation
- 1991-08-05 JP JP21913991A patent/JP3164844B2/ja not_active Expired - Fee Related
- 1991-08-06 TW TW080106149A patent/TW205046B/zh active
-
1993
- 1993-11-12 US US08/151,056 patent/US5434138A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR100191700B1 (ko) | 1999-06-15 |
| IL99062A (en) | 1995-07-31 |
| IE65965B1 (en) | 1995-11-29 |
| IL99062A0 (en) | 1992-07-15 |
| NO913020D0 (no) | 1991-08-02 |
| NO309429B1 (no) | 2001-01-29 |
| DE59100945D1 (de) | 1994-03-10 |
| NO913020L (no) | 1992-02-05 |
| PT98533B (pt) | 1999-01-29 |
| EP0477499A1 (de) | 1992-04-01 |
| JP3164844B2 (ja) | 2001-05-14 |
| US5434138A (en) | 1995-07-18 |
| ZA916097B (en) | 1992-04-29 |
| EP0477499B1 (de) | 1994-01-26 |
| NZ239233A (en) | 1993-09-27 |
| ES2062628T3 (es) | 1994-12-16 |
| TW205046B (pt) | 1993-05-01 |
| AU641035B2 (en) | 1993-09-09 |
| ATE100822T1 (de) | 1994-02-15 |
| CA2048407A1 (en) | 1992-02-05 |
| CA2048407C (en) | 2001-10-23 |
| DK0477499T3 (da) | 1994-05-30 |
| IE912769A1 (en) | 1992-02-12 |
| AU8154891A (en) | 1992-02-06 |
| KR920004417A (ko) | 1992-03-27 |
| JPH05148299A (ja) | 1993-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920218 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19981013 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20040430 |