DK511383A - Fremgangsmaade til fremstilling af piperidindionderivater, der beskytter hjertemuskulaturen med en antiarythmisk aktivitet - Google Patents

Fremgangsmaade til fremstilling af piperidindionderivater, der beskytter hjertemuskulaturen med en antiarythmisk aktivitet Download PDF

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Publication number
DK511383A
DK511383A DK511383A DK511383A DK511383A DK 511383 A DK511383 A DK 511383A DK 511383 A DK511383 A DK 511383A DK 511383 A DK511383 A DK 511383A DK 511383 A DK511383 A DK 511383A
Authority
DK
Denmark
Prior art keywords
derivatives
antiarythmic
indion
piperidine
protecting
Prior art date
Application number
DK511383A
Other languages
Danish (da)
English (en)
Other versions
DK511383D0 (da
Inventor
Claude Bernhart
Werner Cautreels
Patrick Gautier
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK511383D0 publication Critical patent/DK511383D0/da
Publication of DK511383A publication Critical patent/DK511383A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
DK511383A 1982-11-08 1983-11-08 Fremgangsmaade til fremstilling af piperidindionderivater, der beskytter hjertemuskulaturen med en antiarythmisk aktivitet DK511383A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8218706A FR2535721A1 (fr) 1982-11-08 1982-11-08 Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives

Publications (2)

Publication Number Publication Date
DK511383D0 DK511383D0 (da) 1983-11-08
DK511383A true DK511383A (da) 1984-05-09

Family

ID=9279000

Family Applications (1)

Application Number Title Priority Date Filing Date
DK511383A DK511383A (da) 1982-11-08 1983-11-08 Fremgangsmaade til fremstilling af piperidindionderivater, der beskytter hjertemuskulaturen med en antiarythmisk aktivitet

Country Status (29)

Country Link
US (1) US4721710A (el)
EP (1) EP0110755B1 (el)
JP (1) JPS59161377A (el)
KR (1) KR900006721B1 (el)
AT (1) ATE22561T1 (el)
AU (1) AU565519B2 (el)
CA (1) CA1221967A (el)
CS (1) CS244681B2 (el)
DD (3) DD219770A5 (el)
DE (1) DE3366623D1 (el)
DK (1) DK511383A (el)
ES (1) ES8406070A1 (el)
FI (1) FI79536C (el)
FR (1) FR2535721A1 (el)
GR (1) GR78747B (el)
HU (1) HU191494B (el)
IE (1) IE56209B1 (el)
IL (1) IL70099A (el)
MA (1) MA19948A1 (el)
NO (1) NO159852C (el)
NZ (1) NZ206177A (el)
OA (1) OA07582A (el)
PH (1) PH20421A (el)
PL (3) PL139946B1 (el)
PT (1) PT77607B (el)
SG (1) SG1989G (el)
SU (3) SU1333237A3 (el)
YU (3) YU221183A (el)
ZA (1) ZA838065B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668689A (en) * 1984-07-19 1987-05-26 National Research Development Corporation Glutarimide derivatives for treating oestrogen-dependent tumors
US5238947A (en) * 1990-04-12 1993-08-24 University Of Georgia Research Foundation, Inc. Synthetic piperidinediones with cytostatic activity
WO2012158843A2 (en) 2011-05-17 2012-11-22 The Regents Of The University Of California Kinase inhibitors
MX347040B (es) 2011-05-17 2017-04-10 Principia Biopharma Inc Inhibidores de tirosina-cinasas.
WO2012158795A1 (en) 2011-05-17 2012-11-22 Principia Biopharma Inc. Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
US9266895B2 (en) 2012-09-10 2016-02-23 Principia Biopharma Inc. Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors
US8957080B2 (en) 2013-04-09 2015-02-17 Principia Biopharma Inc. Tyrosine kinase inhibitors
SG11201606858RA (en) 2014-02-21 2016-09-29 Principia Biopharma Inc Salts and solid form of a btk inhibitor
EA036269B1 (ru) 2014-12-18 2020-10-21 Принсипиа Биофарма Инк. Лечение пузырчатки
TW201718572A (zh) 2015-06-24 2017-06-01 普林斯匹亞生物製藥公司 酪胺酸激酶抑制劑
MX2018016056A (es) 2016-06-29 2019-07-04 Principia Biopharma Inc Formulaciones de liberacion modificada de 2-[3-[4-amino-3-(2-fluor o-4-fenoxi-fenil)pirazolo[3,4-d]pirimidin-1-il]piperidina-1-carbo nil]-4-metil-4-[4-(oxetan-3-il)piperazin-1-il]pent-2-enenitrilo.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2664424A (en) * 1953-12-29 Dioxo-piperidines
GB1455687A (en) * 1972-12-28 1976-11-17 Aspro Nicholas Ltd Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines
FR2467200A1 (fr) * 1979-10-11 1981-04-17 Clin Midy Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire

Also Published As

Publication number Publication date
YU221183A (en) 1986-06-30
FR2535721B1 (el) 1985-05-17
AU565519B2 (en) 1987-09-17
DK511383D0 (da) 1983-11-08
PL140992B1 (en) 1987-06-30
SU1333238A3 (ru) 1987-08-23
KR840006641A (ko) 1984-12-01
DD219770A5 (de) 1985-03-13
DE3366623D1 (en) 1986-11-06
NZ206177A (en) 1985-11-08
MA19948A1 (fr) 1984-07-01
IL70099A (en) 1987-10-20
HU191494B (en) 1987-02-27
IL70099A0 (en) 1984-01-31
DD229407A5 (de) 1985-11-06
PT77607B (fr) 1986-03-18
FI834087A0 (fi) 1983-11-08
FI834087A (fi) 1984-05-09
YU184285A (en) 1986-06-30
ES527091A0 (es) 1984-07-01
EP0110755B1 (fr) 1986-10-01
SU1316558A3 (ru) 1987-06-07
DD229402A5 (de) 1985-11-06
CA1221967A (en) 1987-05-19
ATE22561T1 (de) 1986-10-15
ZA838065B (en) 1984-06-27
PL249749A1 (en) 1985-03-12
JPS59161377A (ja) 1984-09-12
SU1333237A3 (ru) 1987-08-23
CS244681B2 (en) 1986-08-14
US4721710A (en) 1988-01-26
GR78747B (el) 1984-10-02
FI79536B (fi) 1989-09-29
SG1989G (en) 1989-06-02
EP0110755A1 (fr) 1984-06-13
PL249750A1 (en) 1985-03-12
PT77607A (fr) 1983-12-01
PL140021B1 (en) 1987-03-31
YU184185A (en) 1986-06-30
NO834057L (no) 1984-05-09
NO159852B (no) 1988-11-07
PL244462A1 (en) 1985-02-13
ES8406070A1 (es) 1984-07-01
IE832581L (en) 1984-05-08
FR2535721A1 (fr) 1984-05-11
NO159852C (no) 1989-02-15
IE56209B1 (en) 1991-05-22
FI79536C (fi) 1990-01-10
PH20421A (en) 1987-01-05
OA07582A (fr) 1985-03-31
KR900006721B1 (ko) 1990-09-20
PL139946B1 (en) 1987-03-31
AU2089883A (en) 1984-05-17

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment