DK450086D0 - 12- og 13-bromergolinderivater, fremgangsmaade til fremstilling heraf samt deres anvendelse - Google Patents

12- og 13-bromergolinderivater, fremgangsmaade til fremstilling heraf samt deres anvendelse

Info

Publication number
DK450086D0
DK450086D0 DK450086A DK450086A DK450086D0 DK 450086 D0 DK450086 D0 DK 450086D0 DK 450086 A DK450086 A DK 450086A DK 450086 A DK450086 A DK 450086A DK 450086 D0 DK450086 D0 DK 450086D0
Authority
DK
Denmark
Prior art keywords
derivatives
broomer
golin
procedures
preparing
Prior art date
Application number
DK450086A
Other languages
English (en)
Other versions
DK450086A (da
DK168438B1 (da
Inventor
Gerhard Sauer
Josef Heindl
Gertrud Schroeder
Helmut Wachtel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK450086D0 publication Critical patent/DK450086D0/da
Publication of DK450086A publication Critical patent/DK450086A/da
Application granted granted Critical
Publication of DK168438B1 publication Critical patent/DK168438B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK450086A 1985-09-19 1986-09-19 12- og 13-bromergolinderivater, fremgangsmåde til fremstilling heraf samt mellemprodukt til brug ved deres fremstilling DK168438B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3533675 1985-09-19
DE19853533675 DE3533675A1 (de) 1985-09-19 1985-09-19 Neue 12- und 13-brom-ergolinderivate

Publications (3)

Publication Number Publication Date
DK450086D0 true DK450086D0 (da) 1986-09-19
DK450086A DK450086A (da) 1987-03-20
DK168438B1 DK168438B1 (da) 1994-03-28

Family

ID=6281551

Family Applications (1)

Application Number Title Priority Date Filing Date
DK450086A DK168438B1 (da) 1985-09-19 1986-09-19 12- og 13-bromergolinderivater, fremgangsmåde til fremstilling heraf samt mellemprodukt til brug ved deres fremstilling

Country Status (10)

Country Link
US (1) US4740509A (da)
EP (1) EP0217734B1 (da)
JP (1) JPH0670050B2 (da)
AT (1) ATE69816T1 (da)
CA (1) CA1291121C (da)
CS (1) CS256364B2 (da)
DE (2) DE3533675A1 (da)
DK (1) DK168438B1 (da)
HU (1) HU196599B (da)
IE (1) IE58894B1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
ATE107647T1 (de) * 1984-04-09 1994-07-15 Schering Ag 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3528576A1 (de) * 1985-08-06 1987-02-19 Schering Ag Verfahren zur herstellung von ergolin-thioharnstoffen
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3535929A1 (de) * 1985-10-04 1987-04-09 Schering Ag 1,2-disubstituierte ergolinderivate
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
DE3931819A1 (de) * 1989-09-20 1991-03-28 Schering Ag 13-brom und 13, 14-dibrom-ergoline, ihre herstellung und verwendung in arzneimitteln
DE4001323A1 (de) * 1990-01-15 1991-07-18 Schering Ag 2,13-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE309493C (da) *
DE330912C (de) * 1918-02-07 1920-12-22 Reinhold Braeuer Geschuetz mit verstellbarer Bettung
DE445784C (de) * 1925-12-13 1927-06-17 Siemens Schuckertwerke G M B H Als blanke Schiene verlegte Stromleitung, insbesondere Verstaerkungsleitung, fuer Strom-zufuehrung durch dritte Schiene, bestehend aus mehreren duennen Flachkupferschienen
CH573936A5 (da) * 1971-08-05 1976-03-31 Spofa Vereinigte Pharma Werke
FR2189046B1 (da) * 1972-06-22 1978-07-28 Farmaceutici Italia
CH584220A5 (en) * 1972-09-26 1977-01-31 Sandoz Ag 13-Bromo-lysergic acid derivs - with vigilance-increasing activity
DE2924102A1 (de) * 1979-06-13 1980-12-18 Schering Ag Neue (ergolin-yl)-n'.n'-diaethylharnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3063869D1 (en) * 1979-06-13 1983-07-28 Schering Ag (ergolin-yl)-n', n'-diethyl urea derivatives, their preparation and pharmaceutical compositions containing them
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
ATE107647T1 (de) * 1984-04-09 1994-07-15 Schering Ag 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3413657A1 (de) * 1984-04-09 1985-10-17 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergoline
DE3445784A1 (de) * 1984-12-13 1986-06-26 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von ergolin-derivaten

Also Published As

Publication number Publication date
US4740509A (en) 1988-04-26
DK450086A (da) 1987-03-20
CA1291121C (en) 1991-10-22
IE58894B1 (en) 1993-12-01
HUT41783A (en) 1987-05-28
HU196599B (en) 1988-12-28
DE3533675A1 (de) 1987-03-26
CS256364B2 (en) 1988-04-15
IE862485L (en) 1987-03-19
DE3682645D1 (de) 1992-01-09
ATE69816T1 (de) 1991-12-15
JPS62111983A (ja) 1987-05-22
JPH0670050B2 (ja) 1994-09-07
EP0217734A1 (de) 1987-04-08
DK168438B1 (da) 1994-03-28
EP0217734B1 (de) 1991-11-27
CS675086A2 (en) 1987-08-13

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed