DK449986A - 12- og 13-substituerede ergolinderivater, fremgangsmaade til fremstilling heraf samt deres anvendelse - Google Patents

12- og 13-substituerede ergolinderivater, fremgangsmaade til fremstilling heraf samt deres anvendelse Download PDF

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Publication number
DK449986A
DK449986A DK449986A DK449986A DK449986A DK 449986 A DK449986 A DK 449986A DK 449986 A DK449986 A DK 449986A DK 449986 A DK449986 A DK 449986A DK 449986 A DK449986 A DK 449986A
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DK
Denmark
Prior art keywords
procedures
preparing
ergoline derivatives
substituted ergoline
substituted
Prior art date
Application number
DK449986A
Other languages
English (en)
Other versions
DK168487B1 (da
DK449986D0 (da
Inventor
Gerhard Sauer
Josef Heindl
Gertrud Schroeder
Helmut Wachtel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK449986D0 publication Critical patent/DK449986D0/da
Publication of DK449986A publication Critical patent/DK449986A/da
Application granted granted Critical
Publication of DK168487B1 publication Critical patent/DK168487B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK449986A 1985-09-19 1986-09-19 12- og 13-substituerede ergolinderivater samt en fremgangsmåde til fremstilling deraf DK168487B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853533672 DE3533672A1 (de) 1985-09-19 1985-09-19 Neue 12- und 13-substituierte ergolinderivate
DE3533672 1985-09-19

Publications (3)

Publication Number Publication Date
DK449986D0 DK449986D0 (da) 1986-09-19
DK449986A true DK449986A (da) 1987-03-20
DK168487B1 DK168487B1 (da) 1994-04-05

Family

ID=6281549

Family Applications (1)

Application Number Title Priority Date Filing Date
DK449986A DK168487B1 (da) 1985-09-19 1986-09-19 12- og 13-substituerede ergolinderivater samt en fremgangsmåde til fremstilling deraf

Country Status (12)

Country Link
US (1) US4863929A (da)
EP (1) EP0220129B1 (da)
JP (1) JPH0717640B2 (da)
AT (1) ATE66478T1 (da)
AU (1) AU582275B2 (da)
CA (1) CA1289948C (da)
CS (1) CS261246B2 (da)
DE (2) DE3533672A1 (da)
DK (1) DK168487B1 (da)
ES (1) ES2003101A6 (da)
HU (1) HU201548B (da)
IE (1) IE59340B1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3806374A1 (de) * 1988-02-25 1989-09-07 Schering Ag Neue ergolin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
DE4001323A1 (de) * 1990-01-15 1991-07-18 Schering Ag 2,13-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln
FR2662439B1 (fr) * 1990-05-23 1993-11-19 Rhone Poulenc Chimie Reactif et procede de perfluoroalkylation de substrats nucleophiles par les perfluoroalcanesulfinates de sodium en milieu oxydant.
DE4123587A1 (de) * 1991-07-12 1993-01-14 Schering Ag 2,14-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln
ES2162856T3 (es) * 1992-12-24 2002-01-16 Pharmacia & Upjohn Spa Derivados de ergolina serotoninergicos.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3205169A1 (de) * 1981-02-24 1982-10-14 Sandoz-Patent-GmbH, 7850 Lörrach Neue ergolinderivate, deren herstellung und deren pharmazeutische zusammensetzungen
GB2112382B (en) * 1981-11-06 1985-03-06 Erba Farmitalia Ergoline derivatives
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
DE3528584A1 (de) * 1985-08-06 1987-02-19 Schering Ag Neue 1-alkyl-ergolin-thioharnstoffderivate
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3533675A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-brom-ergolinderivate

Also Published As

Publication number Publication date
DK168487B1 (da) 1994-04-05
IE862486L (en) 1987-03-19
DE3680986D1 (de) 1991-09-26
JPS6270373A (ja) 1987-03-31
EP0220129B1 (de) 1991-08-21
CA1289948C (en) 1991-10-01
HUT41782A (en) 1987-05-28
CS675186A2 (en) 1988-04-15
AU582275B2 (en) 1989-03-16
IE59340B1 (en) 1994-02-09
ES2003101A6 (es) 1988-10-16
DK449986D0 (da) 1986-09-19
EP0220129A3 (en) 1987-08-05
DE3533672A1 (de) 1987-03-26
JPH0717640B2 (ja) 1995-03-01
EP0220129A2 (de) 1987-04-29
CS261246B2 (en) 1989-01-12
AU6273186A (en) 1987-03-26
HU201548B (en) 1990-11-28
ATE66478T1 (de) 1991-09-15
US4863929A (en) 1989-09-05

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