DK415789A - Tetracykliske antidepressive midler - Google Patents

Tetracykliske antidepressive midler

Info

Publication number
DK415789A
DK415789A DK415789A DK415789A DK415789A DK 415789 A DK415789 A DK 415789A DK 415789 A DK415789 A DK 415789A DK 415789 A DK415789 A DK 415789A DK 415789 A DK415789 A DK 415789A
Authority
DK
Denmark
Prior art keywords
tetracyclic
alkyl
different substituents
antidepressive agents
substituents
Prior art date
Application number
DK415789A
Other languages
Danish (da)
English (en)
Other versions
DK415789D0 (da
Inventor
Johannes Hubertus Wieringa
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK415789D0 publication Critical patent/DK415789D0/da
Publication of DK415789A publication Critical patent/DK415789A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK415789A 1988-08-26 1989-08-23 Tetracykliske antidepressive midler DK415789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8802109 1988-08-26

Publications (2)

Publication Number Publication Date
DK415789D0 DK415789D0 (da) 1989-08-23
DK415789A true DK415789A (da) 1990-02-27

Family

ID=19852805

Family Applications (1)

Application Number Title Priority Date Filing Date
DK415789A DK415789A (da) 1988-08-26 1989-08-23 Tetracykliske antidepressive midler

Country Status (16)

Country Link
US (1) US4977158A (es)
EP (1) EP0357126B1 (es)
JP (1) JP2521157B2 (es)
KR (1) KR900003177A (es)
AT (1) ATE104981T1 (es)
AU (1) AU618392B2 (es)
CA (1) CA1325807C (es)
DE (1) DE68914917T2 (es)
DK (1) DK415789A (es)
ES (1) ES2056194T3 (es)
FI (1) FI91638C (es)
IE (1) IE62754B1 (es)
MX (1) MX9203809A (es)
NZ (1) NZ230128A (es)
PT (1) PT91555B (es)
ZA (1) ZA895623B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE203528T1 (de) * 1995-02-08 2001-08-15 Novartis Erfind Verwalt Gmbh Antineurodegenerativ wirksame 10-aminoaliphatyl- dibenz- b,f oxepine
WO1999032108A1 (en) * 1997-12-19 1999-07-01 Akzo Nobel N.V. Org-5222 in the treatment of depression
HRP20020305A8 (en) 2002-04-10 2009-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
HRP20020440B1 (en) 2002-05-21 2008-02-29 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
HRP20020452A2 (en) 2002-05-23 2004-02-29 Pliva D D 1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof
HRP20030956A2 (en) * 2003-11-21 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 1,2-DIAZA-DIBENZO[e,h]AZULENES FOR THE MANU
JP5245428B2 (ja) * 2007-07-06 2013-07-24 住友化学株式会社 トランス−ジベンゾオキセノピロール化合物の製造方法およびその中間体
NZ587896A (en) * 2008-02-19 2011-09-30 Adolor Corp Enantiomers of beloxepin, and the use of beloxepin and its enantiomers to treat pain and other disorders
US20090233958A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation (+)-beloxepin and methods for its synthesis and use
US20090233957A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation (-)-beloxepin and methods for its synthesis and use
US20090233959A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation Beloxepin and analogs for the treatment of pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
US4271179A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof
US4271177A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 2,3,3a,12b-Tetrahydro-1H-dibenzo[2,3;6,7]thiepino[4,5-c]pyrroles and pharmaceutical use thereof
US4158059A (en) * 1976-05-24 1979-06-12 Akzona Incorporated Tension reducing 2,3,4,4a,9,136-hexahydro-dibenz[1,2;5,6]cyclohepta[3,4-c]py
AU604726B2 (en) * 1986-06-26 1991-01-03 Kyowa Hakko Kogyo Co. Ltd. Antiarrhythmic agent

Also Published As

Publication number Publication date
NZ230128A (en) 1990-10-26
JP2521157B2 (ja) 1996-07-31
FI893901A0 (fi) 1989-08-18
DE68914917T2 (de) 1994-08-11
FI91638C (fi) 1994-07-25
ATE104981T1 (de) 1994-05-15
EP0357126B1 (en) 1994-04-27
ES2056194T3 (es) 1994-10-01
DK415789D0 (da) 1989-08-23
US4977158A (en) 1990-12-11
PT91555B (pt) 1995-05-04
DE68914917D1 (de) 1994-06-01
IE62754B1 (en) 1995-02-22
AU618392B2 (en) 1991-12-19
AU4002289A (en) 1990-03-01
IE892363L (en) 1990-02-26
ZA895623B (en) 1990-05-30
FI91638B (fi) 1994-04-15
FI893901A (fi) 1990-02-27
CA1325807C (en) 1994-01-04
EP0357126A1 (en) 1990-03-07
JPH02111776A (ja) 1990-04-24
MX9203809A (es) 1992-07-01
KR900003177A (ko) 1990-03-23
PT91555A (pt) 1990-03-08

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment