DK3848028T5 - Fremgangsmåder til behandling af øjenlidelser - Google Patents

Fremgangsmåder til behandling af øjenlidelser Download PDF

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Publication number
DK3848028T5
DK3848028T5 DK20212556.3T DK20212556T DK3848028T5 DK 3848028 T5 DK3848028 T5 DK 3848028T5 DK 20212556 T DK20212556 T DK 20212556T DK 3848028 T5 DK3848028 T5 DK 3848028T5
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DK
Denmark
Prior art keywords
methods
eye disorders
treating eye
treating
disorders
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DK20212556.3T
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Danish (da)
English (en)
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DK3848028T3 (da
Inventor
Douglas Michael Ackermann Jr
James Loudin
Kenneth J Mandell
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Oyster Point Pharma Inc
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Publication of DK3848028T3 publication Critical patent/DK3848028T3/da
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emergency Medicine (AREA)
DK20212556.3T 2014-10-20 2015-10-19 Fremgangsmåder til behandling af øjenlidelser DK3848028T5 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462066280P 2014-10-20 2014-10-20
US201562100844P 2015-01-07 2015-01-07
EP15852340.7A EP3209295B2 (en) 2014-10-20 2015-10-19 Methods of treating ocular conditions

Publications (2)

Publication Number Publication Date
DK3848028T3 DK3848028T3 (da) 2024-08-26
DK3848028T5 true DK3848028T5 (da) 2025-01-20

Family

ID=55748136

Family Applications (2)

Application Number Title Priority Date Filing Date
DK20212556.3T DK3848028T5 (da) 2014-10-20 2015-10-19 Fremgangsmåder til behandling af øjenlidelser
DK15852340.7T DK3209295T4 (da) 2014-10-20 2015-10-19 Fremgangsmåder til behandling af øjenlidelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK15852340.7T DK3209295T4 (da) 2014-10-20 2015-10-19 Fremgangsmåder til behandling af øjenlidelser

Country Status (21)

Country Link
US (14) US9532944B2 (enExample)
EP (3) EP4413974A3 (enExample)
JP (3) JP6873906B2 (enExample)
KR (2) KR102511955B1 (enExample)
CN (3) CN107106542B (enExample)
AU (2) AU2015336216B2 (enExample)
BR (2) BR112017008097B1 (enExample)
CA (1) CA2965129C (enExample)
DK (2) DK3848028T5 (enExample)
EA (1) EA035335B1 (enExample)
ES (2) ES2848977T5 (enExample)
FI (1) FI3848028T3 (enExample)
IL (3) IL318427A (enExample)
MX (2) MX392383B (enExample)
MY (1) MY186870A (enExample)
PH (1) PH12017500602A1 (enExample)
PL (1) PL3848028T3 (enExample)
PT (2) PT3209295T (enExample)
SG (2) SG10202011669PA (enExample)
WO (1) WO2016064759A1 (enExample)
ZA (1) ZA201703467B (enExample)

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EP4413974A3 (en) 2014-10-20 2024-10-09 Oyster Point Pharma, Inc. Methods of treating ocular conditions
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TW202019424A (zh) * 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之方法
CN112638364A (zh) 2018-07-10 2021-04-09 奥伊斯特普安生物制药公司 用于治疗眼部病症的正向别构调节剂和烟碱型乙酰胆碱受体激动剂的组合
TW202206078A (zh) 2020-04-28 2022-02-16 美商奧伊斯特普安生物製藥公司 局部投與菸鹼乙醯膽鹼受體促效劑用以抑制冠狀病毒感染
WO2025037323A1 (en) * 2023-08-12 2025-02-20 Pavan Kumar Kothapuvari Pharmaceutical compositions for treatment of dry eye disease and associated disorders
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TW202019424A (zh) 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之方法
CN112638364A (zh) 2018-07-10 2021-04-09 奥伊斯特普安生物制药公司 用于治疗眼部病症的正向别构调节剂和烟碱型乙酰胆碱受体激动剂的组合

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DK3209295T3 (da) 2021-03-01
US11224598B2 (en) 2022-01-18
US20170239244A1 (en) 2017-08-24
US20160106744A1 (en) 2016-04-21
EP3209295A1 (en) 2017-08-30
EP3209295B1 (en) 2020-12-09
JP2021038250A (ja) 2021-03-11
US20200246336A1 (en) 2020-08-06
US20250275963A1 (en) 2025-09-04
CA2965129A1 (en) 2016-04-28
US20250255865A1 (en) 2025-08-14
CN111956650A (zh) 2020-11-20
US20230226052A1 (en) 2023-07-20
EP3209295B2 (en) 2023-12-06
EP3848028A1 (en) 2021-07-14
MY186870A (en) 2021-08-26
WO2016064759A1 (en) 2016-04-28
IL251769A0 (en) 2017-06-29
DK3848028T3 (da) 2024-08-26
US20160106745A1 (en) 2016-04-21
KR102511955B1 (ko) 2023-03-22
US11903942B2 (en) 2024-02-20
CN111956803B (zh) 2025-10-31
AU2015336216B2 (en) 2020-05-21
BR122022025737B1 (pt) 2023-12-26
AU2020213351B2 (en) 2023-04-06
PT3209295T (pt) 2021-02-05
ZA201703467B (en) 2023-12-20
JP2023024574A (ja) 2023-02-16
US9504644B2 (en) 2016-11-29
CN107106542A (zh) 2017-08-29
SG10202011669PA (en) 2020-12-30
KR20170086040A (ko) 2017-07-25
KR20230042144A (ko) 2023-03-27
US10456396B2 (en) 2019-10-29
MX2017005064A (es) 2018-02-23
MX2022005888A (es) 2022-06-14
IL293188A (en) 2022-07-01
US9597284B2 (en) 2017-03-21
IL293188B2 (en) 2025-06-01
JP6873906B2 (ja) 2021-05-19
KR102601505B1 (ko) 2023-11-14
JP7257371B2 (ja) 2023-04-13
EA201790893A1 (ru) 2018-01-31
AU2020213351A1 (en) 2020-08-27
JP7502404B2 (ja) 2024-06-18
US11903941B2 (en) 2024-02-20
EP3848028B9 (en) 2024-10-16
JP2017531044A (ja) 2017-10-19
BR112017008097B1 (pt) 2023-03-28
SG11201703135XA (en) 2017-05-30
BR112017008097A2 (pt) 2018-02-20
US9532944B2 (en) 2017-01-03
US20230226054A1 (en) 2023-07-20
PT3848028T (pt) 2024-09-20
FI3848028T3 (fi) 2024-08-21
US20250235449A1 (en) 2025-07-24
EA035335B1 (ru) 2020-05-28
IL251769B (en) 2022-06-01
US11911380B2 (en) 2024-02-27
CA2965129C (en) 2024-03-12
IL293188B1 (en) 2025-02-01
MX392383B (es) 2025-03-24
US11903943B2 (en) 2024-02-20
PL3848028T3 (pl) 2024-11-18
CN111956650B (zh) 2024-06-04
AU2015336216A1 (en) 2017-06-08
EP3209295A4 (en) 2018-05-23
US20230226053A1 (en) 2023-07-20
US20160106665A1 (en) 2016-04-21
ES2848977T5 (es) 2024-06-06
EP3848028B1 (en) 2024-05-29
IL318427A (en) 2025-03-01
EP4413974A3 (en) 2024-10-09
ES2986830T3 (es) 2024-11-12
CN111956803A (zh) 2020-11-20
US20160106746A1 (en) 2016-04-21
US20220233528A1 (en) 2022-07-28
DK3209295T4 (da) 2024-02-26
CN107106542B (zh) 2020-05-08
US9504645B2 (en) 2016-11-29
PH12017500602A1 (en) 2017-09-04
EP4413974A2 (en) 2024-08-14
ES2848977T3 (es) 2021-08-13
US20240173318A1 (en) 2024-05-30

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