DK3797155T3 - Optimering af nk-92-cellevækst ved hjælp af poloxamer - Google Patents

Optimering af nk-92-cellevækst ved hjælp af poloxamer Download PDF

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Publication number
DK3797155T3
DK3797155T3 DK19730234.2T DK19730234T DK3797155T3 DK 3797155 T3 DK3797155 T3 DK 3797155T3 DK 19730234 T DK19730234 T DK 19730234T DK 3797155 T3 DK3797155 T3 DK 3797155T3
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DK
Denmark
Prior art keywords
poloxamer
optimization
cell growth
growth
cell
Prior art date
Application number
DK19730234.2T
Other languages
English (en)
Inventor
Shannyn Bessette
Diemchi Nguyen
Syed Raza Ali
Manju Saxena
Original Assignee
Immunitybio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Immunitybio Inc filed Critical Immunitybio Inc
Application granted granted Critical
Publication of DK3797155T3 publication Critical patent/DK3797155T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0646Natural killers cells [NK], NKT cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/34Sugars
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/50Soluble polymers, e.g. polyethyleneglycol [PEG]

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
DK19730234.2T 2018-05-22 2019-05-21 Optimering af nk-92-cellevækst ved hjælp af poloxamer DK3797155T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862674723P 2018-05-22 2018-05-22
PCT/US2019/033312 WO2019226649A1 (en) 2018-05-22 2019-05-21 Optimization of nk-92 cell growth using poloxamer

Publications (1)

Publication Number Publication Date
DK3797155T3 true DK3797155T3 (da) 2022-08-29

Family

ID=66827004

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19730234.2T DK3797155T3 (da) 2018-05-22 2019-05-21 Optimering af nk-92-cellevækst ved hjælp af poloxamer

Country Status (11)

Country Link
US (1) US20210363484A1 (da)
EP (1) EP3797155B1 (da)
JP (1) JP7208262B2 (da)
KR (2) KR102587512B1 (da)
CN (1) CN112166184A (da)
AU (1) AU2019272583B2 (da)
CA (1) CA3098471C (da)
DK (1) DK3797155T3 (da)
ES (1) ES2925553T3 (da)
IL (1) IL278384B2 (da)
WO (1) WO2019226649A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115521915B (zh) * 2022-11-30 2023-03-21 江苏谱新生物医药有限公司 一种car-nk细胞及其制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08500242A (ja) * 1992-06-24 1996-01-16 メルク エンド カンパニー インコーポレーテッド インターロイキン1β前駆体の転換酵素をコードするDNA
EP2243827B2 (en) * 1996-08-30 2017-11-22 Life Technologies Corporation Serum-free mammalian cell culture medium, and uses thereof
US8034332B2 (en) 1997-04-30 2011-10-11 Conkwest, Inc. Interleukin-secreting natural killer cell lines and methods of use
DE69834257T2 (de) 1997-04-30 2007-01-04 Klingemann, Hans Natürliche killerzelllinien und verfahren zu ihrer verwendung
WO1999024566A1 (en) 1997-11-06 1999-05-20 Roche Diagnostics Gmbh Tumor-specific antigens, methods for their production and their use for immunization and diagnosis
EP1117691A1 (en) 1998-10-05 2001-07-25 Ludwig Institute For Cancer Research Methods for producing human tumor antigen specific antibodies
US7098008B2 (en) 2000-04-25 2006-08-29 Ic&G Do. Ltd. Selected primers for detection of MAGE or GAGE genes for diagnosis of cancer and methods of use
US20050153419A1 (en) * 2003-12-23 2005-07-14 Schering Corporation Methods for producing cell lines stable in serum-free medium suspension culture
CA3052445C (en) 2004-07-10 2023-08-22 Kerry S. Campbell Genetically modified human natural killer cell lines
CA2803391C (en) 2010-06-22 2021-11-09 Neogenix Oncology, Inc. Npc1 antibodies that bind a muc5ac epitope
PT3012268T (pt) 2010-09-08 2018-01-31 Chemotherapeutisches Forschungsinstitut Georg Speyer Haus Recetores de antigénio quimérico com uma região de charneira otimizada
CN104126009B (zh) 2011-10-07 2019-05-10 国立大学法人三重大学 嵌合抗原受体
AU2012325915A1 (en) 2011-10-20 2014-04-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-CD22 chimeric antigen receptors
AU2013312838B2 (en) 2012-09-04 2018-11-29 Cellectis Multi-chain chimeric antigen receptor and uses thereof
US20150329640A1 (en) 2012-12-20 2015-11-19 Bluebird Bio, Inc. Chimeric antigen receptors and immune cells targeting b cell malignancies
AU2017340633B2 (en) 2016-10-05 2024-01-11 University Of Central Florida Research Foundation, Inc. Methods and compositions related to NK cell and anti-PDL1 cancer therapies
AU2017356942A1 (en) 2016-11-08 2019-05-23 Calithera Biosciences, Inc. Arginase inhibitor combination therapies
CN107674860A (zh) * 2017-07-14 2018-02-09 上海源培生物科技股份有限公司 Nk92细胞无血清培养基

Also Published As

Publication number Publication date
CA3098471C (en) 2023-04-18
KR20230146128A (ko) 2023-10-18
CA3098471A1 (en) 2019-11-28
IL278384A (da) 2020-12-31
JP2021524743A (ja) 2021-09-16
EP3797155B1 (en) 2022-06-15
AU2019272583B2 (en) 2022-01-06
AU2019272583A1 (en) 2020-11-05
IL278384B2 (en) 2024-02-01
KR102587512B1 (ko) 2023-10-11
EP3797155A1 (en) 2021-03-31
CN112166184A (zh) 2021-01-01
KR20210011978A (ko) 2021-02-02
IL278384B1 (en) 2023-10-01
US20210363484A1 (en) 2021-11-25
ES2925553T3 (es) 2022-10-18
WO2019226649A1 (en) 2019-11-28
JP7208262B2 (ja) 2023-01-18

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