DK374089A - Il-1alfa-derivater og medkiament til behandling af thrombocytopenia - Google Patents

Il-1alfa-derivater og medkiament til behandling af thrombocytopenia Download PDF

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Publication number
DK374089A
DK374089A DK374089A DK374089A DK374089A DK 374089 A DK374089 A DK 374089A DK 374089 A DK374089 A DK 374089A DK 374089 A DK374089 A DK 374089A DK 374089 A DK374089 A DK 374089A
Authority
DK
Denmark
Prior art keywords
1alfa
medicines
derivatives
treating thrombocytopenia
thrombocytopenia
Prior art date
Application number
DK374089A
Other languages
English (en)
Other versions
DK374089D0 (da
DK172424B1 (da
Inventor
Yoshikatsu Hirai
Takashi Kamogashira
Yoshihiro Masui
Satoru Nakai
Mayumi Kaneta
Kazuyoshi Kawai
Koutoku Aihara
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of DK374089D0 publication Critical patent/DK374089D0/da
Publication of DK374089A publication Critical patent/DK374089A/da
Application granted granted Critical
Publication of DK172424B1 publication Critical patent/DK172424B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK198903740A 1988-07-29 1989-07-28 IL-1alfa-Derivater, farmaceutisk præparat omfattende sådanne derivater, anvendelse af IL-1alfa-derivater, DNA sekvenser kod DK172424B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP19100988 1988-07-29
JP19100988 1988-07-29
JP19541988 1988-08-04
JP19541988 1988-08-04

Publications (3)

Publication Number Publication Date
DK374089D0 DK374089D0 (da) 1989-07-28
DK374089A true DK374089A (da) 1990-01-30
DK172424B1 DK172424B1 (da) 1998-06-08

Family

ID=26506426

Family Applications (2)

Application Number Title Priority Date Filing Date
DK198903740A DK172424B1 (da) 1988-07-29 1989-07-28 IL-1alfa-Derivater, farmaceutisk præparat omfattende sådanne derivater, anvendelse af IL-1alfa-derivater, DNA sekvenser kod
DK199701011A DK172589B1 (da) 1988-07-29 1997-09-05 Medikament indeholdende IL-1beta eller et derivat deraf til behandling af thrombocytopenia

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK199701011A DK172589B1 (da) 1988-07-29 1997-09-05 Medikament indeholdende IL-1beta eller et derivat deraf til behandling af thrombocytopenia

Country Status (5)

Country Link
US (2) US5120534A (da)
EP (2) EP0352816A3 (da)
KR (1) KR960008010B1 (da)
AU (1) AU627480B2 (da)
DK (2) DK172424B1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202117A (en) * 1988-08-24 1993-04-13 Koichiro Tsuji Method of treating thrombi with g-csf
DE68916237T2 (de) * 1988-12-06 1994-11-10 Otsuka Pharma Co Ltd Stabilisierte interleukin-1-beta enthaltende zusammensetzung.
KR920702230A (ko) * 1990-08-10 1992-09-03 오쯔까 아끼히꼬 간염예방·치료제
US5723117A (en) * 1990-08-10 1998-03-03 Otsuka Pharmaceutical Co., Ltd. Use of interleukin-1 (IL-1) to inhibit development of hepatitis
JP2818834B2 (ja) * 1991-08-12 1998-10-30 大塚製薬株式会社 ＩＬ−１α安定化医薬製剤
KR101504893B1 (ko) * 2008-11-07 2015-03-23 유나이티드 테크놀로지스 유티 에이지 인터루킨-1 알파 및 펩티드를 함유하는 화장료 조성물
EP2464330B1 (en) * 2009-09-29 2016-03-23 United Technologies UT AG Oral care compositions containing human recombinant interleukin-1
US8603456B2 (en) 2009-10-08 2013-12-10 United Technologies Ut Ag Method of treating hair loss with compositions containing interleukin-1
KR101610861B1 (ko) * 2014-07-28 2016-04-11 (주)케어젠 골분화 촉진능 및 치주인대섬유모세포 활성 촉진능을 갖는 펩타이드 및 이의 용도

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK172052B1 (da) * 1984-12-21 1997-09-29 Otsuka Pharma Co Ltd Antitumor-aktivt stof, fremgangsmåde til dets fremstilling, lægemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme transformet med en sådan vektor
EP0188920B1 (en) * 1984-12-25 1993-09-29 Dainippon Pharmaceutical Co., Ltd. Interleukin 1 and its derivative
AU577856B2 (en) * 1985-01-17 1988-10-06 Immunex Corporation Cloning and characterization of the human interleukin 1 gene
DE3683186D1 (de) * 1985-04-25 1992-02-13 Hoffmann La Roche Rekombinantes humaninterleukin-1.
JPH07100663B2 (ja) * 1985-12-23 1995-11-01 大日本製薬株式会社 インタ−ロイキン１を有効成分とする感染症予防・治療剤
JPS62185097A (ja) * 1986-02-07 1987-08-13 Dainippon Pharmaceut Co Ltd インタ−ロイキン１活性を示すポリペプチド
US5831022A (en) * 1986-02-18 1998-11-03 Hoffmann-La Roche Inc. Purification of recombinant human IL-1α
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
JP2591615B2 (ja) * 1986-03-14 1997-03-19 大塚製薬株式会社 インターロイキン−１β誘導体及び医薬
US4808611A (en) * 1986-07-30 1989-02-28 Immunex Corporation Use of interleukin-1 to induce development of multipotent hemopoietic cell populations
US5017692A (en) * 1986-09-04 1991-05-21 Schering Corporation Truncated human interleukin-a alpha
US5093242A (en) * 1986-10-02 1992-03-03 Massachusetts Institute Of Technology Methods of generating desired amino-terminal residues in proteins
US5047505A (en) * 1987-01-27 1991-09-10 Du Pont Merck Pharmaceutical Company High level expression in E. coli of soluble mature HIL-1beta and derivatives with altered biological activity
JP2616784B2 (ja) * 1987-11-19 1997-06-04 大日本製薬株式会社 ヒトインターロイキン１ポリペプチド生産用高度形質発現プラスミド
ZA89202B (en) * 1988-01-15 1989-09-27 Hoffmann La Roche Recombinant human interleukin-1 alpha polypeptides
JPH029899A (ja) * 1988-02-22 1990-01-12 Dainippon Pharmaceut Co Ltd 新規ポリペプチド及びそれをコードするｄｎａ並びにそれらの製法

Also Published As

Publication number Publication date
AU627480B2 (en) 1992-08-27
DK172589B1 (da) 1999-02-08
EP0644203A1 (en) 1995-03-22
US5120534A (en) 1992-06-09
EP0352816A2 (en) 1990-01-31
KR910002465A (ko) 1991-02-25
DK374089D0 (da) 1989-07-28
US5756675A (en) 1998-05-26
KR960008010B1 (ko) 1996-06-19
AU3909389A (en) 1990-02-01
EP0352816A3 (en) 1991-03-20
DK101197A (da) 1997-09-05
DK172424B1 (da) 1998-06-08

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed