DE68916237T2 - Stabilisierte interleukin-1-beta enthaltende zusammensetzung. - Google Patents

Stabilisierte interleukin-1-beta enthaltende zusammensetzung.

Info

Publication number
DE68916237T2
DE68916237T2 DE68916237T DE68916237T DE68916237T2 DE 68916237 T2 DE68916237 T2 DE 68916237T2 DE 68916237 T DE68916237 T DE 68916237T DE 68916237 T DE68916237 T DE 68916237T DE 68916237 T2 DE68916237 T2 DE 68916237T2
Authority
DE
Germany
Prior art keywords
beta
composition containing
stabilized composition
containing interleukin
interleukin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68916237T
Other languages
English (en)
Other versions
DE68916237D1 (de
Inventor
Yuji Sugahara
Hirotsugu Kaise
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP63309264A external-priority patent/JPH0676332B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of DE68916237D1 publication Critical patent/DE68916237D1/de
Application granted granted Critical
Publication of DE68916237T2 publication Critical patent/DE68916237T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2006—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DE68916237T 1988-12-06 1989-12-02 Stabilisierte interleukin-1-beta enthaltende zusammensetzung. Expired - Fee Related DE68916237T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63309264A JPH0676332B2 (ja) 1988-03-09 1988-12-06 インターロイキン‐１βの安定化組成物
PCT/JP1989/001212 WO1990006127A1 (en) 1988-12-06 1989-12-02 STABILIZED COMPOSITION OF INTERLEUKIN-1$g(b)

Publications (2)

Publication Number Publication Date
DE68916237D1 DE68916237D1 (de) 1994-07-21
DE68916237T2 true DE68916237T2 (de) 1994-11-10

Family

ID=17990905

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68916237T Expired - Fee Related DE68916237T2 (de) 1988-12-06 1989-12-02 Stabilisierte interleukin-1-beta enthaltende zusammensetzung.

Country Status (6)

Country Link
EP (1) EP0401379B1 (de)
KR (1) KR910700061A (de)
DE (1) DE68916237T2 (de)
DK (1) DK185690A (de)
ES (1) ES2054099T3 (de)
WO (1) WO1990006127A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616460A (en) * 1995-06-07 1997-04-01 Abbott Laboratories Buffer composition for reagents for immunoassay
DE60333821D1 (de) * 2002-02-28 2010-09-30 Nipro Corp Stabilisierte albumin-zubereitungen
EA023680B1 (ru) * 2009-03-17 2016-06-30 Общество С Ограниченной Ответственностью "Сенгара" Интерлейкин-1 бета в косметических композициях и способы его использования

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58206513A (ja) * 1982-05-28 1983-12-01 Eisai Co Ltd セクレチン吸着防止組成物および方法
EP0158487B1 (de) * 1984-04-09 1991-08-28 Takeda Chemical Industries, Ltd. Stabile Interleukin-2-Zusammensetzung
JPS61293926A (ja) * 1985-06-21 1986-12-24 Toray Ind Inc インタ−ロイキン−２組成物
JP2591615B2 (ja) * 1986-03-14 1997-03-19 大塚製薬株式会社 インターロイキン−１β誘導体及び医薬
CA1292686C (en) * 1986-10-27 1991-12-03 Ze'ev Shaked Pharmaceutical compositions of recombinant interleukin-2 and formulation process
US4816436A (en) * 1986-10-29 1989-03-28 Immunex Corporation Anti-arthritic use of interleukin-1 proteins
EP0352816A3 (de) * 1988-07-29 1991-03-20 Otsuka Pharmaceutical Co., Ltd. IL-1 alpha Derivate und Arzneimittel gegen Thrombozytopenie
JP2554528B2 (ja) * 1988-09-19 1996-11-13 大塚製薬株式会社 副腎皮質刺激ホルモン分泌能検査薬
ZA902663B (en) * 1989-04-07 1991-12-24 Syntex Inc Interleukin-1 formulation
JP3221120B2 (ja) * 1992-12-25 2001-10-22 ソニー株式会社 復号装置

Also Published As

Publication number Publication date
WO1990006127A1 (en) 1990-06-14
EP0401379A4 (en) 1992-05-06
DE68916237D1 (de) 1994-07-21
DK185690D0 (da) 1990-08-03
DK185690A (da) 1990-10-05
KR910700061A (ko) 1991-03-13
EP0401379B1 (de) 1994-06-15
ES2054099T3 (es) 1994-08-01
EP0401379A1 (de) 1990-12-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee