DK373782A - Fremgangsmaade til fremstilling af hidtil ukendte pyrimidin- eller s-triazinderivater - Google Patents
Fremgangsmaade til fremstilling af hidtil ukendte pyrimidin- eller s-triazinderivater Download PDFInfo
- Publication number
- DK373782A DK373782A DK373782A DK373782A DK373782A DK 373782 A DK373782 A DK 373782A DK 373782 A DK373782 A DK 373782A DK 373782 A DK373782 A DK 373782A DK 373782 A DK373782 A DK 373782A
- Authority
- DK
- Denmark
- Prior art keywords
- pyrimidine
- procedure
- triazine derivatives
- unknown
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/42—One nitrogen atom
- C07D251/44—One nitrogen atom with halogen atoms attached to the two other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/42—One nitrogen atom
- C07D251/46—One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8123580A IT1211096B (it) | 1981-08-20 | 1981-08-20 | Pirimidine e s.triazinici adattivita' ipolipidemizzante. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK373782A true DK373782A (da) | 1983-02-21 |
Family
ID=11208290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK373782A DK373782A (da) | 1981-08-20 | 1982-08-20 | Fremgangsmaade til fremstilling af hidtil ukendte pyrimidin- eller s-triazinderivater |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4559345A (es) |
| EP (1) | EP0073328A1 (es) |
| JP (1) | JPS5869870A (es) |
| CA (1) | CA1173036A (es) |
| DE (1) | DE73328T1 (es) |
| DK (1) | DK373782A (es) |
| ES (3) | ES8401037A1 (es) |
| IT (1) | IT1211096B (es) |
| PH (1) | PH17607A (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK130584A (da) * | 1983-04-08 | 1984-10-09 | Ciba Geigy Ag | N-(2-nitrophenyl)-4-amino-pyrimidin-derivater samt deres fremstilling og anvendelse som mikrobicider |
| US4542216A (en) * | 1984-03-27 | 1985-09-17 | Ciba Geigy Corporation | Process for producing fluoroalkoxyaminopyrimidines |
| DE3445293A1 (de) * | 1984-12-12 | 1986-06-12 | Bayer Ag, 5090 Leverkusen | Neue 2,4-diaminopyrimidine |
| JPH0631238B2 (ja) * | 1985-08-01 | 1994-04-27 | 日産化学工業株式会社 | ピラゾロ〔４，３−ｄ〕ピリミジン誘導体 |
| GB8911287D0 (en) * | 1989-05-17 | 1989-07-05 | Ciba Geigy Ag | Lubricant compositions |
| DE4104466A1 (de) * | 1990-03-09 | 1991-09-12 | Huels Chemische Werke Ag | Quartaere ammoniumsalze von thiobarbitursaeuren und verfahren zu deren herstellung |
| AU1507199A (en) | 1997-12-15 | 1999-07-05 | Yamanouchi Pharmaceutical Co., Ltd. | Novel pyrimidine-5-carboxamide derivatives |
| CA2357781A1 (en) | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Multicyclic compounds which inhibit leukocyte adhesion mediated by vla-4 |
| CA2359112A1 (en) * | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Fused ring heteroaryl and heterocyclic compounds which inhibit leukocyte adhesion mediated by vla-4 |
| JP2002535314A (ja) * | 1999-01-22 | 2002-10-22 | エラン ファーマシューティカルズ，インコーポレイテッド | Ｖｌａ−４により媒介される白血球接着を阻害する化合物 |
| US6436904B1 (en) * | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| DE60009883T2 (de) | 1999-03-01 | 2005-04-07 | Elan Pharmaceuticals, Inc., San Francisco | Alpha-aminoessigsäure derivate als alpha 4 beta 7- rezeptor antagonisten |
| HUP0400708A3 (en) * | 2000-12-07 | 2007-10-29 | Cv Therapeutics | Substituted 1,3,5-triazine and pyrimidine derivatives, their use and pharmaceutical compositions containing them |
| WO2002100836A2 (en) * | 2001-06-12 | 2002-12-19 | Active Pass Pharmaceuticals, Inc. | Compounds, compositions and methods for modulating beta-amyloid production |
| TWI281470B (en) * | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| TW200307671A (en) * | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| DE102005025161A1 (de) * | 2005-06-01 | 2006-12-07 | Phenion Gmbh & Co. Kg | Derivate des Pyrimidins und Triazins und deren Verwendung |
| CN101273035A (zh) * | 2005-09-29 | 2008-09-24 | 伊兰制药公司 | 抑制由vla-4介导的白细胞粘附的氨基甲酸酯化合物 |
| NZ567270A (en) * | 2005-09-29 | 2011-06-30 | Elan Pharm Inc | Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| EA017110B1 (ru) * | 2006-02-27 | 2012-09-28 | Элан Фамэсьютикэлс, Инк. | ПИРИМИДИНИЛСУЛЬФОНАМИДНЫЕ СОЕДИНЕНИЯ (ВАРИАНТЫ), СПОСОБ ПОЛУЧЕНИЯ ПИРИМИДИНИЛСУЛЬФОНАМИДНЫХ СОЕДИНЕНИЙ (ВАРИАНТЫ), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, ОПОСРЕДОВАННОГО ИНТЕГРИНОМ α4, СПОСОБ СНИЖЕНИЯ И/ИЛИ ПРЕДУПРЕЖДЕНИЯ ВОСПАЛИТЕЛЬНОГО КОМПОНЕНТА ЗАБОЛЕВАНИЯ ИЛИ АУТОИММУННОГО ОТВЕТА |
| MX2011011326A (es) * | 2009-04-27 | 2012-02-13 | Elan Pharm Inc | Antagonistas de piridinona de las integrinas alfa-4. |
| US20230399320A1 (en) * | 2020-11-06 | 2023-12-14 | Pelemed Co., Ltd. | Novel capsid assembly inhibitor |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB744867A (en) * | 1952-10-29 | 1956-02-15 | American Cyanamid Co | Improvements relating to 2-substituted-mercapto-4-amino-6-disubstituted-aminopyrimidines and acid addition salts thereof |
| US3321478A (en) * | 1963-09-20 | 1967-05-23 | American Cyanamid Co | Aminoethoxyphenyl amine, ether, and sulfide derivatives of pyrimidine |
| FR1413722A (fr) * | 1963-11-12 | 1965-10-08 | Geigy Ag J R | Nouveaux dérivés de la pyrimidine, leur préparation et leurs applications |
| CH481986A (de) * | 1967-05-24 | 1969-11-30 | Geigy Ag J R | Verfahren zur Herstellung von wasserlöslichen Farbsalzen von Azopyrimidinfarbstoffen |
| US3814761A (en) * | 1972-03-31 | 1974-06-04 | American Home Prod | (2-pyrimidinylthio)alkanoic acids,esters,amides and hydrazides |
| US3974162A (en) * | 1972-12-21 | 1976-08-10 | American Home Products Corporation | 4-Pyrimidinylthioacetic acid derivatives |
| DE2549161A1 (de) * | 1975-11-03 | 1977-05-12 | Henkel & Cie Gmbh | Farbentwickler fuer farbphotographische entwicklungsverfahren |
| IT1063074B (it) * | 1976-03-17 | 1985-02-11 | Lpb Ist Farm | Ammidi di acidi(z-pirimidiniltio)al canoici quali agent antilipemici |
-
1981
- 1981-08-20 IT IT8123580A patent/IT1211096B/it active
-
1982
- 1982-07-15 EP EP82106347A patent/EP0073328A1/en not_active Ceased
- 1982-07-15 DE DE198282106347T patent/DE73328T1/de active Pending
- 1982-07-20 PH PH27601A patent/PH17607A/en unknown
- 1982-07-21 CA CA000407790A patent/CA1173036A/en not_active Expired
- 1982-07-21 US US06/400,434 patent/US4559345A/en not_active Expired - Fee Related
- 1982-08-19 ES ES515104A patent/ES8401037A1/es not_active Expired
- 1982-08-19 JP JP57144575A patent/JPS5869870A/ja active Pending
- 1982-08-20 DK DK373782A patent/DK373782A/da unknown
-
1983
- 1983-07-16 ES ES524186A patent/ES524186A0/es active Granted
- 1983-07-16 ES ES524185A patent/ES8504741A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IT1211096B (it) | 1989-09-29 |
| ES8500912A1 (es) | 1984-11-16 |
| US4559345A (en) | 1985-12-17 |
| DE73328T1 (de) | 1983-07-21 |
| ES524185A0 (es) | 1985-05-01 |
| PH17607A (en) | 1984-10-05 |
| ES515104A0 (es) | 1983-12-16 |
| CA1173036A (en) | 1984-08-21 |
| IT8123580A0 (it) | 1981-08-20 |
| ES8504741A1 (es) | 1985-05-01 |
| ES8401037A1 (es) | 1983-12-16 |
| JPS5869870A (ja) | 1983-04-26 |
| ES524186A0 (es) | 1984-11-16 |
| EP0073328A1 (en) | 1983-03-09 |
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