DK36881A - Fremgangsmaade til fremstilling af lavmolekylaer heparin - Google Patents
Fremgangsmaade til fremstilling af lavmolekylaer heparinInfo
- Publication number
- DK36881A DK36881A DK36881A DK36881A DK36881A DK 36881 A DK36881 A DK 36881A DK 36881 A DK36881 A DK 36881A DK 36881 A DK36881 A DK 36881A DK 36881 A DK36881 A DK 36881A
- Authority
- DK
- Denmark
- Prior art keywords
- low molecule
- preparing low
- molecule heparin
- heparin
- preparing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11577880A | 1980-01-28 | 1980-01-28 | |
US11577880 | 1980-01-28 | ||
US15567480 | 1980-06-02 | ||
US06/155,674 US4281108A (en) | 1980-01-28 | 1980-06-02 | Process for obtaining low molecular weight heparins endowed with elevated pharmacological properties, and product so obtained |
Publications (2)
Publication Number | Publication Date |
---|---|
DK36881A true DK36881A (da) | 1981-07-29 |
DK168297B1 DK168297B1 (da) | 1994-03-07 |
Family
ID=26813554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK036881A DK168297B1 (da) | 1980-01-28 | 1981-01-27 | Fremgangsmåde til fremstilling af lavmolekylær heparin ud fra normal heparin |
Country Status (7)
Country | Link |
---|---|
US (1) | US4281108A (da) |
DE (1) | DE3102621A1 (da) |
DK (1) | DK168297B1 (da) |
FR (1) | FR2474508B1 (da) |
GB (1) | GB2068011B (da) |
IT (1) | IT1141954B (da) |
NL (1) | NL189043C (da) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2619136A (en) * | 1950-07-10 | 1952-11-25 | John D Nash | Rectangular framework clamp |
US2670773A (en) * | 1950-12-18 | 1954-03-02 | Edward L Avery | Concrete form clamp and anchor holder |
US3262595A (en) * | 1963-09-27 | 1966-07-26 | Johns Manville | Lift truck clamp attachment |
EP0006537A1 (de) * | 1978-06-24 | 1980-01-09 | Peter Strasser | Einspannrahmen für die Herstellung rechteckiger Rahmen, insbesondere Bilderrahmen |
DE3236578A1 (de) * | 1982-10-02 | 1984-04-26 | Bessey & Sohn Gmbh & Co, 7000 Stuttgart | Rahmenspanngeraet |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2478646A2 (fr) * | 1980-03-20 | 1981-09-25 | Choay Sa | Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir |
USRE35770E (en) * | 1978-11-06 | 1998-04-14 | Choay, S.A. | Oligosaccharides having anti-Xa activity and pharmaceutical compositions containing them |
US4500519A (en) * | 1978-11-06 | 1985-02-19 | Choay S.A. | Mucopolysaccharides having biological properties, preparation and method of use |
SE449753B (sv) * | 1978-11-06 | 1987-05-18 | Choay Sa | Mukopolysackaridkomposition med reglerande verkan pa koagulation, lekemedel innehallande densamma samt forfarande for framstellning derav |
US4692435A (en) * | 1978-11-06 | 1987-09-08 | Choay, S.A. | Mucopolysaccharide composition having a regulatory action on coagulation, medicament containing same and process of preparation |
FR2440376A1 (fr) * | 1978-11-06 | 1980-05-30 | Choay Sa | Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir |
US4826827A (en) * | 1979-10-05 | 1989-05-02 | Choay S.A. | Short chained oligosaccharides having biological properties, a process for making the same and the use thereof as drugs |
IL61201A (en) * | 1979-10-05 | 1984-09-30 | Choay Sa | Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them |
US4438261A (en) | 1980-05-19 | 1984-03-20 | Riker Laboratories, Inc. | Anticoagulant substance |
CA1171375A (en) * | 1980-09-15 | 1984-07-24 | Ulf P.F. Lindahl | Oligosaccharides having selective anticoagulation activity |
US4396762A (en) * | 1981-08-24 | 1983-08-02 | Massachusetts Institute Of Technology | Heparinase derived anticoagulants |
CA1195322A (en) * | 1982-07-19 | 1985-10-15 | Eduardo Amaya | Process for manufacturing low molecular weight heparins by depolymerization of normal heparin |
FR2538404B1 (da) * | 1982-12-28 | 1985-08-23 | Anic Spa | |
US4533549A (en) * | 1983-01-04 | 1985-08-06 | Lasker Sigmund E | Antithrombotic agent |
IT1195497B (it) * | 1983-03-08 | 1988-10-19 | Opocrin Spa | Procedimento per la preparazione di frazioni oligosaccaridiche dotate di proprieta' farmacologiche per degradazione chimica di eparina |
FR2543145B1 (fr) * | 1983-03-24 | 1986-10-17 | Sanofi Sa | Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante |
FR2553287B1 (fr) * | 1983-10-18 | 1986-09-12 | Choay Sa | Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire |
IT1214609B (it) * | 1985-05-17 | 1990-01-18 | Opocrin Spa | Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono. |
FR2584728B1 (fr) * | 1985-07-12 | 1987-11-20 | Choay Sa | Procede de sulfatation de glycosaminoglycanes et de leurs fragments |
US4788307A (en) * | 1986-04-30 | 1988-11-29 | Choay S.A. | Oligosaccharidic fractions devoid or practically devoid of antithrombotic activity |
US4745106A (en) * | 1986-08-20 | 1988-05-17 | Griffin Charles C | Heparin derivatives having improved anti-Xa specificity |
US4745107A (en) * | 1986-08-20 | 1988-05-17 | Foley Kevin M | Heparin derivatives with improved permeability |
US4942156A (en) * | 1986-08-20 | 1990-07-17 | Hepar Industries, Inc. | Low molecular weight heparin derivatives having improved anti-Xa specificity |
US4745105A (en) * | 1986-08-20 | 1988-05-17 | Griffin Charles C | Low molecular weight heparin derivatives with improved permeability |
IT1230582B (it) | 1988-10-21 | 1991-10-28 | Opocrin S P A Lab Farmabiologi | Oliogosaccaridi di dermatan solfato ed eparina aventi attivita' antiaterosclerotica |
SK120193A3 (en) * | 1991-05-02 | 1994-07-06 | Yeda Res & Dev | Pharmaceutical composition for the prevention and/or treatment of pathological processes |
US5744457A (en) * | 1995-03-31 | 1998-04-28 | Hamilton Civic Hospitals Research Development Inc. | Compositions and methods for inhibiting thrombogenesis |
US5763427A (en) * | 1995-03-31 | 1998-06-09 | Hamilton Civic Hospitals Research Development Inc. | Compositions and methods for inhibiting thrombogenesis |
US6001820A (en) * | 1995-03-31 | 1999-12-14 | Hamilton Civic Hospitals Research Development Inc. | Compositions and methods for inhibiting thrombogenesis |
CA2235223A1 (en) | 1995-10-30 | 1997-05-09 | Massachusetts Institute Of Technology | Rationally designed polysaccharide lyases derived from heparinase i |
US5767269A (en) * | 1996-10-01 | 1998-06-16 | Hamilton Civic Hospitals Research Development Inc. | Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics |
IT1290814B1 (it) * | 1997-03-24 | 1998-12-11 | Istituto Scient Di Chimica E B | Glicosaminoglicani aventi elevata attivita' antitrombotica |
US7056504B1 (en) | 1998-08-27 | 2006-06-06 | Massachusetts Institute Of Technology | Rationally designed heparinases derived from heparinase I and II |
WO2000012726A2 (en) * | 1998-08-27 | 2000-03-09 | Massachusetts Institute Of Technology | Rationally designed heparinases derived from heparinase i and ii |
EP1190364A2 (en) * | 1999-04-23 | 2002-03-27 | Massachusetts Institute Of Technology | System and method for polymer notation |
US6869789B2 (en) * | 2000-03-08 | 2005-03-22 | Massachusetts Institute Of Technology | Heparinase III and uses thereof |
KR20000053816A (ko) * | 2000-04-20 | 2000-09-05 | 조석형 | 저분자 다당류 및 그의 올리고당 제조방법 |
ES2640975T3 (es) | 2000-09-12 | 2017-11-07 | Massachusetts Institute Of Technology | Métodos y productos relacionados con heparina de peso molecular bajo |
AU2002224408B2 (en) * | 2000-10-18 | 2007-08-23 | Massachusetts Institute Of Technology | Methods and products related to pulmonary delivery of polysaccharides |
US7084118B2 (en) * | 2002-02-22 | 2006-08-01 | Genentech, Inc. | Combination treatment with t-PA variant and low molecular weight heparin |
WO2004022153A2 (en) * | 2002-09-05 | 2004-03-18 | Genentech, Inc. | Infusion catheter having an integrated doppler transducer |
JP2022540849A (ja) | 2019-07-09 | 2022-09-20 | オプティムヴィア、エルエルシー | 抗凝固性多糖類の合成方法 |
EP4182452A1 (en) | 2020-07-14 | 2023-05-24 | Optimvia, LLC | Methods for synthesizing non-anticoagulant heparan sulfate |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB867064A (en) * | 1959-05-16 | 1961-05-03 | Roussel Uclaf | New derivatives of heparin and processes for their production |
NL123338C (da) * | 1961-12-08 | |||
IT1083903B (it) * | 1977-08-09 | 1985-05-25 | Lobo Srl | Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche |
-
1980
- 1980-06-02 US US06/155,674 patent/US4281108A/en not_active Expired - Lifetime
-
1981
- 1981-01-20 GB GB8101642A patent/GB2068011B/en not_active Expired
- 1981-01-26 IT IT19321/81A patent/IT1141954B/it active
- 1981-01-26 NL NLAANVRAGE8100354,A patent/NL189043C/xx not_active IP Right Cessation
- 1981-01-27 DE DE19813102621 patent/DE3102621A1/de active Granted
- 1981-01-27 DK DK036881A patent/DK168297B1/da not_active IP Right Cessation
- 1981-01-27 FR FR8101508A patent/FR2474508B1/fr not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2619136A (en) * | 1950-07-10 | 1952-11-25 | John D Nash | Rectangular framework clamp |
US2670773A (en) * | 1950-12-18 | 1954-03-02 | Edward L Avery | Concrete form clamp and anchor holder |
US3262595A (en) * | 1963-09-27 | 1966-07-26 | Johns Manville | Lift truck clamp attachment |
EP0006537A1 (de) * | 1978-06-24 | 1980-01-09 | Peter Strasser | Einspannrahmen für die Herstellung rechteckiger Rahmen, insbesondere Bilderrahmen |
DE3236578A1 (de) * | 1982-10-02 | 1984-04-26 | Bessey & Sohn Gmbh & Co, 7000 Stuttgart | Rahmenspanngeraet |
Also Published As
Publication number | Publication date |
---|---|
IT8119321A0 (it) | 1981-01-26 |
FR2474508A1 (fr) | 1981-07-31 |
NL189043B (nl) | 1992-07-16 |
NL8100354A (nl) | 1981-08-17 |
IT1141954B (it) | 1986-10-08 |
DK168297B1 (da) | 1994-03-07 |
DE3102621A1 (de) | 1981-12-10 |
DE3102621C2 (da) | 1992-08-06 |
GB2068011A (en) | 1981-08-05 |
FR2474508B1 (fr) | 1986-03-07 |
NL189043C (nl) | 1992-12-16 |
US4281108A (en) | 1981-07-28 |
GB2068011B (en) | 1983-07-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK36881A (da) | Fremgangsmaade til fremstilling af lavmolekylaer heparin | |
DK350083A (da) | Fremgangsmaade til fremstilling af phenylethanolaminer | |
DK417981A (da) | Fremgangsmaade til fremstilling af 3-aryl-5-isothiazol-derivater | |
DK88081A (da) | Fremgangsmaade til fremstilling af tetrazolderivater | |
DK319281A (da) | Femgangsmaade til fremstilling af benzisoselenazoloner | |
DK210083A (da) | Fremgangsmaade til fremstilling af 6a,10a-trans-hexahydrodibenzopyranoner | |
DK582883A (da) | Fremgangsmaade til fremstilling af modelis | |
DK212381A (da) | Fremgangsmaade til fremstilling af polynucleotider | |
DK479981A (da) | Fremgangsmaade til fremstilling af 3-aryl-3-hydroxyphthalimidiner | |
DK355584D0 (da) | Fremgangsmaade til fremstilling af 3-exomethylen-cephalosporiner | |
DK40883A (da) | Fremgangsmaade til fremstilling af benzothienylallylaminer | |
DK424083D0 (da) | Fremgangsmade til fremstilling af anthracyclinglycosider | |
DK231481A (da) | Fremgangsmaade til fremstilling af diacetonektetogulonsyre | |
DK501582A (da) | Fremgangsmaade til fremstilling af acylcyanider | |
DK331381A (da) | Fremgangsmaade til fremstilling af 1-klor-1-pmetoxybenzoylformaldoxim-n-metylkarbamat | |
DK105082A (da) | Fremgangsmaade til fremstilling af substituerede trifluormethylphenyl-tetrahydropyridiner | |
DK486177A (da) | Fremgangsmaade til fremstilling af heparin | |
DK548081A (da) | Fremgangsmaade til fremstilling af buspiron | |
DK446683D0 (da) | Fremgangsmade til fremstilling af 6-anilino-5,8-quinoxalindioner | |
DK385983A (da) | Fremgangsmaade til fremstilling af 1-oxacephamer | |
DK219483D0 (da) | Fremgangsmade til fremstilling af anthracyclinglycosider | |
DK212884A (da) | Fremgangsmaade til fremstilling af isoxazolylimidazolidinoner | |
DK238081A (da) | Fremgangsmaade til fremstilling af tetramisolanaloge | |
DK96077A (da) | Fremgangsmaade til fremstilling af heparin | |
DK385381A (da) | Fremgangsmaade til fremstilling af pyraziner |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |