DK105082A - Fremgangsmaade til fremstilling af substituerede trifluormethylphenyl-tetrahydropyridiner - Google Patents

Fremgangsmaade til fremstilling af substituerede trifluormethylphenyl-tetrahydropyridiner Download PDF

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Publication number
DK105082A
DK105082A DK105082A DK105082A DK105082A DK 105082 A DK105082 A DK 105082A DK 105082 A DK105082 A DK 105082A DK 105082 A DK105082 A DK 105082A DK 105082 A DK105082 A DK 105082A
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DK
Denmark
Prior art keywords
trifluormethylphenyl
tetrahydropyridines
preparing substituted
substituted
preparing
Prior art date
Application number
DK105082A
Other languages
English (en)
Other versions
DK152843B (da
DK152843C (da
Inventor
D Nisato
E Crisafulli
A Bianchetti
P Carminati
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK105082A publication Critical patent/DK105082A/da
Publication of DK152843B publication Critical patent/DK152843B/da
Application granted granted Critical
Publication of DK152843C publication Critical patent/DK152843C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK105082A 1981-03-11 1982-03-10 Analogifremgangsmaade til fremstilling af n-substituerede 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridiner og farmaceutisk acceptable salte deraf DK152843C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8104890 1981-03-11
FR8104890A FR2501682A1 (fr) 1981-03-11 1981-03-11 Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant

Publications (3)

Publication Number Publication Date
DK105082A true DK105082A (da) 1982-09-12
DK152843B DK152843B (da) 1988-05-24
DK152843C DK152843C (da) 1988-10-03

Family

ID=9256120

Family Applications (1)

Application Number Title Priority Date Filing Date
DK105082A DK152843C (da) 1981-03-11 1982-03-10 Analogifremgangsmaade til fremstilling af n-substituerede 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridiner og farmaceutisk acceptable salte deraf

Country Status (20)

Country Link
US (2) US4472408A (da)
EP (1) EP0060176B1 (da)
JP (1) JPS57159766A (da)
AR (2) AR229174A1 (da)
AT (1) ATE11044T1 (da)
AU (1) AU547692B2 (da)
CA (1) CA1196643A (da)
DE (1) DE3261731D1 (da)
DK (1) DK152843C (da)
ES (3) ES8305329A1 (da)
FI (1) FI76786C (da)
FR (1) FR2501682A1 (da)
GR (1) GR79178B (da)
IE (1) IE52365B1 (da)
IL (1) IL65169A0 (da)
NO (1) NO158736C (da)
NZ (1) NZ199973A (da)
PT (1) PT74559B (da)
YU (2) YU50782A (da)
ZA (1) ZA821518B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
DE3438394A1 (de) * 1984-10-19 1986-04-30 Merck Patent Gmbh, 6100 Darmstadt Pyridinderivate
HU198454B (en) * 1987-12-14 1989-10-30 Richter Gedeon Vegyeszet Process for production of new derivatives of tetrahydrospiridin and medical compositions containing these compounds
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2650505B1 (fr) * 1989-08-07 1994-06-03 Midy Spa Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
FR2672213B1 (fr) * 1991-02-05 1995-03-10 Sanofi Sa Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125488A (en) * 1964-03-17 Method of inducing analgesia by
US3072648A (en) * 1963-01-08 X-phenyl-s
GB881894A (en) * 1958-04-22 1961-11-08 Paul Adriaan Jan Janssen Tetrahydropyridine derivatives
FR86403E (fr) * 1959-05-01 1966-02-04 May & Baker Ltd Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
GB984364A (en) * 1961-07-28 1965-02-24 May & Baker Ltd Substituted piperidines and tetrahydropyridines
GB948071A (en) * 1959-05-01 1964-01-29 May & Baker Ltd New heterocyclic compounds
US3284457A (en) * 1964-01-17 1966-11-08 Degussa 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
US3626066A (en) * 1967-12-13 1971-12-07 Robins Co Inc A H Arylpyridinyl-alkyl alcohol derivatives in compositions and methods for tranquilizing mammals
AT287711B (de) * 1968-06-25 1971-02-10 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen 1-Alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl-carbonsäureestern sowie deren Säureadditionssalzen und quaternären Ammoniumverbindungen
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals
US4012374A (en) * 1975-09-29 1977-03-15 E. R. Squibb & Sons, Inc. 1-[[4-Phenyl-piperidinyl (or tetrahydropyridinyl)]alkyl]-2,6-piperidinedione and analogs
US4024151A (en) * 1975-09-29 1977-05-17 E. R. Squibb & Sons, Inc. 4-Phenylpiperidinyl (and 4-phenyl-tetrahydropyridinyl) alkylamino-oxoalkanoic acids
FR2416886A1 (fr) * 1978-02-08 1979-09-07 Roussel Uclaf Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments

Also Published As

Publication number Publication date
FI76786B (fi) 1988-08-31
US4472408A (en) 1984-09-18
AU547692B2 (en) 1985-10-31
DK152843B (da) 1988-05-24
IL65169A0 (en) 1982-05-31
ES8407023A1 (es) 1984-09-01
ES527456A0 (es) 1984-09-01
YU50782A (en) 1985-03-20
YU195484A (en) 1985-03-20
IE52365B1 (en) 1987-09-30
NO158736C (no) 1988-10-26
DK152843C (da) 1988-10-03
ZA821518B (en) 1983-01-26
AR228330A1 (es) 1983-02-15
AR229174A1 (es) 1983-06-30
NZ199973A (en) 1984-10-19
AU8111182A (en) 1982-09-16
JPH0435459B2 (da) 1992-06-11
PT74559A (fr) 1982-04-01
FR2501682A1 (fr) 1982-09-17
NO158736B (no) 1988-07-18
ATE11044T1 (de) 1985-01-15
DE3261731D1 (en) 1985-02-14
ES510302A0 (es) 1983-04-01
GR79178B (da) 1984-10-02
CA1196643A (en) 1985-11-12
IE820455L (en) 1982-09-11
EP0060176A1 (fr) 1982-09-15
NO820767L (no) 1982-09-13
ES518545A0 (es) 1984-03-01
JPS57159766A (en) 1982-10-01
FI820826L (fi) 1982-09-12
EP0060176B1 (fr) 1985-01-02
FI76786C (fi) 1988-12-12
ES8403109A1 (es) 1984-03-01
FR2501682B1 (da) 1984-03-16
ES8305329A1 (es) 1983-04-01
US4602024A (en) 1986-07-22
PT74559B (fr) 1983-11-10

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